Similarly, our results provided clearly evidence for a synergistic interaction between RM and RS leading to highly significant (P<0.01) reductions in the Cd accumulation of edible parts of the four vegetables.
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ANOVA and Duncan’s test were conducted for variance analysis ( P < 0.05 was considered significant and P < 0.01 was considered highly significant), and graphs were generated using GraphPad Prism 7.0.
This intronic SNP was found to be in LD ( r 2 = 0.64) with a synonymous DDX58 SNP (rs3205166/Val800Val), which also demonstrated an allele dose relationship with higher neutralizing antibody levels (approximately 40% increase in antibodies), although this association did not reach statistical significance at p ≤ 0.01 ( p = 0.017, Table 2 ).
Other results for these two groups between the different time points were highly significant (p < 0.01 and p < 0.001), except for time points A and B, that is, before and 7 days after surgery.
The resulting differences were stated as significant if the p -values were less than 0.05 (* p ≤ 0.05) or as highly significant for p -values less than 0.01 (** p ≤ 0.01) or less than 0.001 (*** p ≤ 0.001).
When examining global precedence, a significant group difference was apparent indicating a larger global processing advantage in the low AQ group, when compared with the high AQ group ( p < .01; see Fig. 2 ).
Results Our results showed highly significant difference in the registrars group compared to consultants for cumulative cardiopulmonary bypass time, and aortic cross clamp time; p <0.01.
Levene’s test for homogeneity of variance produced a near-significant result (F(3, 64) = 1.63, p < 0.01), suggesting that the variances across groups were marginally different and necessitating careful interpretation of results.
Differences were considered significant at p <0.05 (*) and extremely significant at p <0.01 (**).
The observed concurrence of interaction maps does not occur merely by chance as it is validated by two permutation tests for pair-wise comparisons of graphs, where the observed overlap of interactions generated is highly significant for all comparisons ( P < 0.01) [ 12 ].
A highly significant (Figure 1 D, P < 0.01) difference between the normal and tumor tissues was observed as follows: 23.5% (4 of 17) negative, 29.4% (5 of 17) weak positive and 47.1% (8 of 17) strong positive staining of fibulin-1 in normal bladder specimens, whereas 54.0% (75 of 139) negative, 35.2% (49 of 139) weak positive and 10.8% (15 of 139) strong positive staining of fibulin-1 in bladder cancer samples.
This is the reason why FM is highly significant ( P <0.01).
Under normal conditions, OE plants grew similarly to the WT and 35 lines ( Figure 4 A–E); however, under four different stress treatments, OE plants grew better than the WT and 35S plants, had higher chlorophyll content, and had lower water loss rates than the control lines ( Figure 4 F,G), and both findings were highly significant ( p < 0.01).
The difference among the three groups was statistically highly significant ( P < 0.01).
To better reflect the biological significance of the observed differences in collagen-related parameters, we have supplemented the effect size estimates (partial η 2 ) for all key indicators, including %SHG and %Agg ( Supplementary Table S3 ), which showed that the grouping factor (sex × treatment time) exerted a statistically highly significant effect on ( p < 0.01).
There was highly significant decrease (p<0.01) in hemoglobin, total erythrocyte count, packed cell volume and total leukocyte count, serum glucose, total protein, globulin and albumin level and highly significant increase in aspartate aminotransferase and alanine aminotransferase level as compared to healthy control animals in Group I and II.
Nominally significant associations were detected ( p ~10 −2 –10 −3 ) within CNTN4 (contactin 4) and CTNNA3 (catenin alpha 3).
Our results show an increasing trend in measured levels from R1 to R3 (p<0.01), i.e. before and after Lahore city, which indicate the impact of the municipal sewage waste from the 10 million city Lahore.
The PV and BD values of the composite system showed significant positive correlations with the ΔH r and RC after 14 d of storage ( P < 0.05), while exhibiting highly significant negative correlations with both the SDS and ReS contents, as well as with the FWHM values at 480 cm −1 after 14 d of storage ( P < 0.01).
There was a highly significant positive relationship between the invasively derived measure of PV CAP and GX CAP with exercise ( r = 0.86, P < 0.01) ( Fig. 1 ).
The phylum Verrucomicrobia showed, on the one hand, a uniform distribution among the considered sites, with no correlation to salinity, but also, on the other hand, a highly significant dependence on organic matter, with a Spearman's rho value for C org of 0.667, for p>0.01.
As can be seen from the results reported in Table 2 , the data with * are statistically significant as p < 0.05, while the data with ** are highly significant as p < 0.01.
Carrageenan-induced paw edema in rats The effect of OWB extract on the carrageenan-induced rat paw edema, presented in Table S4 in File S1 , showed that the extract at 400 mg/kg inhibited 56.75% of paw edema, which is highly significant (P<0.01), compared to the animals treated with the standard drug indomethacin.
As for the predictive validity of the tool, highly significant correlations were found between the total PMQ score and the number of aberrant drug-related behaviors at 2-month ( r = 0.58; P < 0.01), 4-month ( r = 0.67; P < 0.01), and 6-month follow-ups ( r = 0.52; P < 0.01).
Highly significant heterogeneity was found among the 13 studies ( χ 2 = 262.30, I 2 = 95%, P < 0.01), indicating their heterogeneity.