One multiple regression used “imagery” as the dependent variable and the other three conditions as independent variables, which revealed a highly significant relationship and a moderate positive relationship, F (3) = 17.5, p < 0.0001, r = 0.68.
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The same trend was observed on the fifth day with a very highly significant difference (df = 27; F = 12.67; p < 0.0001) observed between the treatments.
Furthermore, the compound induced a highly significant (P < 0.0001) antiproliferative effect at 72 vs. 96h exposure period (concentration range 31.25–250 μM in MDA-MB-231 and 15.62–125 μM in MDA-MB-468 cell line) as indicated by the significant reduction in the IC 50 values, in particular for MDA-MB-468 cells.
Interaction of any two of the three tested variables and the combined three variables was highly significant ( P < 0.0001, Mixed models).
There was a significant trend toward better OS for early-stage patients in the entire cohort and in the CCRT group (P <0.0001 and <0.036, respectively).
Critically, the main effect of Emotion type was highly significant [ F 1 (1,59) = 200.95, p < 0.0001, η 2 = 0.23; F 2 (1,18) = 8.84, p < 0.009, η 2 = 0.27], as putatively basic emotions ( M = 5.72) were rated higher than non-basic emotions ( M = 4.61).
bryosalmonae in Water A highly significant treatment effect was observed ( F 3;16 = 33.05, p < 0.0001), indicating that Tb eDNA concentration in water was significantly higher in treatments involving trout compared to those without, suggesting active spore release via urine (Figure 2 , Table 1 , Figure S1 ).
We obtained a highly significant area under curve (AUC) which gave a good separation between Control and ALL (sensitivity is 93.22% and specificity is 93.33%, P <0.0001) ( Figure 1 B and Table 2 ).
Prevalence and trend of TTIs in blood donors according to donor status The analysis of first-time donors (who comprised 23.3% of all donors) showed a decreasing trend in the prevalence of HBV ( P < 0.0001, R: -0.98), HIV ( P < 0.18, R: -0.49), HCV ( P < 0.0001, R: − 0.98) and HTLV 1/2 ( P < 0.0001, R: − 0.95) from 2010 to 2018.
The correlation was highly significant (Spearman’s ρ = 0.74, p < 0.0001) and comparable to that between immunogenicity and MHC complex stability.
Multiple regression analysis of the experimental data yielded the following second-order polynomial equation (Equation (1)), which describes the relationship between the response variable and the independent variables: (1) Oil yield (%) = 33.84 + 0.5783A + 0.8342B + 0.4008C + 0.8633D + 0.5550AB + 0.2425AC + 0.1675AD + 0.6150BC − 0.2725BD + 0.2550CD − 2.08A 2 − 1.31B 2 − 2.09C 2 − 1.32D 2 As shown in Table 3 , the regression model was highly significant ( p < 0.0001), while the lack-of-fit test was not significant ( p > 0.05), indicating that the model is statistically valid and well-fitted to the experimental data.
Both of these variables were highly significant predictors of BU (p<0.0001).
Moreover, the prevalence of subjects defined as being overweight/obese, having central obesity, and those with dyslipidaemia showed an increasing trend in all age groups (P-value<0.0001).
In addition, GRA35 DNA/mRNA prime–boost regimens resulted in a highly significant reduction in brain cyst numbers ( p < 0.0001) compared with the control group.
Experiments that supplemented carotenoids rather than correlations with concentrations of carotenoids in blood resulted in significantly larger effect sizes (p = 0.006), but an analysis without the supplementation studies still yielded a highly significant overall effect size ( table 2 , p<0.0001).
Pooling data from all groups resulted in a highly significant correlation explaining 34% of the variance in the dataset, r 2 = 0.34, p < 0.0001 ( Figure 5 ).
We also show that the dramatic decrease in oocyst numbers in dsCactus females (median=0, p< 0.0001, ANOVA, Dunn’s multiple comparison test) relative to LacZ controls (median=127) (Figure 6C), is also associated with a strong and highly significant increase (13-fold) in TM7318 mRNA associated with the midgut of dsCactus infected females, relative to dsLacZ (p=0.0001, Mann-Whitney test) 24 h post-infection (Figure 6D), indicative Megacyte recruitment to the midgut.
Quantification of the vascular density is presented ( Fig 2B ), where analysis (ANOVA) indicated a highly significant difference between the groups ( p < .0001).
A highly significant association between CEI and mortality was noted (p < 0.0001), with mortality reduction of 8.1 (CI: 6.6–9.6) per 1000 units CEI.
Highly significant mitonuclear interaction terms were observed in each condition (ANOVA on the random effect model y ij = μ ~ mt i + n j + (mt × n) ij + ε ij , P < 0.0001, Table S 4 ) and could explain 10.8 to 31.5% of the total phenotypic variances (Fig. 1 c, Table S 5 ).
Both predictors are highly significant ( p < 0.0001 ).
Copulsatility of the GH and GHRH hormone series was highly significant in both patients ( P < 0.0001).
The difference between the treatments was marginally significant at Day 4 and 7 (P = 0.0532 and 0.0560, respectively), and highly significant by Day 14 (P < 0.0001; Fig 5D ).
Results A mean neutralization titer 50% of 230 (range, <8‐1765) was seen for the 100 convalescent plasma units, with highly significant ( P < .0001) yet quantitatively limited (R 2 = 0.2830) correlation with results of the ELISA.
There was a highly significant negative correlation between the changes in PINP and BMD in lumbar spine and femoral neck from baseline to 12 months in all patients (r(s) = -0.68, P < 0.0001, and -0.45, P < 0.0001, respectively), and in pre- and post-menopausal patients separately.