However, the Cochran–Armitage test showed that there was a highly significant decreasing trend ( P < 0.0001) in the early neonatal mortality rates across the entire period from 2000 through 2010.
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Results from the interrupted time-series model demonstrated a highly significant drop of $67 per year in OOP costs between 2012 and 2013 ( P <.0001) and continued annual decreases of $2.32 per year ( P =.042).
Indeed, we observed complete or near complete LD for all pairs of SNPs with sufficiently high frequencies (only alleles with frequencies in the range 0.05–0.95 were included in the analysis because estimates of LD for low-frequency alleles in small samples are not informative): 85% of all pairwise r 2 values were highly significant (Exact p -value <0.0001).
showed a trendP<0.0001
On the other hand, the group of subjects who received PI vaccination showed a trend toward an increase in the median IgG titer (median values of 0.3 to 579 (P<0.0001), 0.00–401.4 (P = 0.3125), and 971.3 to 2163 (P = 0.3008) in group 1,2, and 3 respectively), except slight decrease of IgG value for Group 4 (median value of 1067 to 1021; P = 0.9717).
Critically, simple main effects confirmed that differences in atypicality between fluency and mastery portraits were highly significant for both phases, t1 ( M diff = 3.00), F (1, 11) = 214.08, p < .0001, p 2 = .951 and t2 ( M diff = 2.20), F (1, 11) = 36.46, p < .0001, p 2 = .768.
The highly significant likelihood ratio tests (p<0.0001) for each model confirm that each subsequent set of variables provided a significantly better fit to the data than the previous one.
This was particularly evident for MSWC 30% and MIX 30% for which the correlation values between DOC and labile As were highly significant ( r = − 0.79, P < 0.0001 for MSWC 30%; r = − 0. 90, P < 0.000001 for MIX 30%).
ANOVA supported the quadratic RSM model for TAC (Table 3 ) with a highly significant model ( F = 27.21, p < 0.0001; R 2 ~ 0.96).
Combined correlation analyses using all protein analytes resulted in a highly significant correlation ( P < 0.0001) between DISSECT-flow and imaging data, and between DISSECT-flow and immunoblotting data.
By aggregating the two subgroups with low risk and three subgroups with medium risk, patients could be assigned to three risk groups (high, medium, low) with a highly significant ( p < 0.0001) five-fold difference in risk (Table 5 and insert in Fig. 2 ).
The correlations between these measures are highly significant (Pearson p < 0.0001).
Despite this, at year 8, the intervention group maintained small but significantly lower FM and LM overall, and the mean effect over the entire eight-year period was highly significant (P<0.0001).
A regression analysis of calving pattern and total cost of rearing also showed a highly significant difference ( P <0.0001) between the cost of rearing on all-year-round calving herds and spring and autumn calving herds (data not shown).
According to data published by the Companion Animal Parasite Council website ( www.capcvet.org ), the percentage of Ohio dogs tested positive for exposure to the Lyme disease spirochete by the SNAP 4Dx Plus Test was 0.39% (218 of 54,963) for 2011, 0.55% (250 of 45,376) for 2012, 0.56% for 2013 (543 of 96,016), and 0.62% (102 of 16,343) for 2014 as of April 23, 2014, showing a significant trend of increase ( P < 0.0001, Chi-square test for trend).
Similarly, there were also highly significant differences among the various time points (F = 109.57, P < 0.0001).
Comparison of survival curves of the two cohorts of mice revealed a highly significant prolonged survival for TRAMP mice (p<0.0001).
Correlation between capillary TSH and venous fT4 testing There was a strong correlation between capillary TSH at screening and confirmatory venous fT4 testing following referral with a highly significant Spearman’s rank correlation coefficient of −0.707355 (p<0.0001, 95% CI after using Fisher’s Z transformed −0.760912 to −0.644225).
Further we found that tests for differences in the distributions of transition types for different starting syllables across contexts were also highly significant (not random), including for the m syllable [T X 2 (obs.) = 5167.109, df = 684, p < 0.0001; Figure 9 and Appendix A in Supplementary Material]; pair-wise comparisons using Chi-squared tests for each pair of contexts showed strong statistical differences (Figure 9 and Appendix A in Supplementary Material: p < 0.0001).
Discrimination models were examined using OPLS-DA, revealing highly predictive (Q2 > 0.63) and highly significant ( p < 0.0001) differences between sTBI patients and OI controls using metabolic profiles obtained by DI/LC–MS/MS and 1 H-NMR on day 4 post-injuries (Fig. 1 ).
Copulsatility of the GH and GHRH hormone series was highly significant in both patients ( P < 0.0001).
There was a highly significant interaction between population and temperature 2 ( F 3,2126 = 15.34, P < 0.0001) indicating that the pattern of ticks questing with temperature varied between populations.
In that study, NGR was found to have highly significant associations with BOAS in the bulldog breeds (French Bulldogs p<0.0001, Bulldogs p<0.0001), but not Pugs (p>0.05).
The seminal fluid concentrations of Pb (SfPb) and Cd (SfCd) were measured in 118 of the 149 subjects, and a highly significant (p < 0.0001) correlation was found between BPb and SfPb levels (r = 0.571) and between BCd and SfCd levels (r = 0.490).
For bromine, a statistically highly significant difference was observed between the two groups, with much lower values in the patient group: 1086 ± 244 μg/L vs. 4137 ± 770 μg/L ( p < 0.0001).
The difference between median value of C PRSA and C RAW was highly significant (0.79 [IQR 0.69–0.90] and 0.29 [IQR 0.17–0.47], respectively; p<0.0001).