The according risk of developing oral cancer was 0.65% and 0.18%, whereby the risk difference of 0.47% was highly significant ( p < 0.0001; Log-Rank test).
Excerpts
Nevertheless, the improvements remained highly significant ( p < 0.0001) for patients who received the Dermgraft and Dermgraft with SW treatments (Fig. 5 ).
However, the increase in the fitness cost for growth in the biofilm was highly significant ( P < 0.0001 by a two-tailed t test) for streptomycin ( rpsL K42R) and rifampicin ( rpoB S531L) resistance.
This difference is highly significant ( P < 0.0001), demonstrating that the X chromosome is enriched for female-biased single transcript genes.
These models established HR and patient age as highly significant (p < 0.0001) predictors of NST.
The model was highly significant ( P < 0.0001), with a coefficient of determination R 2 = 0.9937 and an adjusted R 2 = 0.9891.
Within-group analysis using paired t-tests demonstrated a highly significant reduction in SPADI scores from baseline at all follow-up intervals in both groups (p < 0.0001).
The sEPSC frequency in these cells was 4.20 ± 4.36 Hz, which was greater than the mEPSC frequency (1.06 ± 1.39 Hz), and this difference was highly significant ( P < 0.0001, Wilcoxon signed-rank test, Fig. 9 D).
The mean difference of 8.73 was found to be statistically highly significant (P<0.0001).
Treating cages as replicates, this difference in mating success is highly significant ( t 38 = 5.16, p < 0.0001).
score was very strong and highly significant (ρ = 0.874, p < 0.0001).
A highly significant difference ( p < 0.0001, effect size = 0.319) is observed between protein–protein (Peptide = 0) and protein–peptide (Peptide = 1) complexes ( Figure 1 b), with a noticeably lower median affinity for the latter.
For pTau181, we observed highly significant effect modification by amyloid status (interaction β = 0.65, p < 0.0001).
Nominally significant MetaXcan results ( p < 10 −4 ) were investigated using gene set enrichment analysis. 2.8 Look‐Up of Results From Prior WL in COPD GWAS We compared significant results from our prior GWAS of WL in COPD [ 9 ] with results from the current analyses.
Based on 20 independent runs, a paired t-test on accuracy values confirms a highly significant difference (t(19) = 55.37, p < 0.0001), providing strong evidence against the null hypothesis.
officinalis phospholipids showed a robust and highly significant reduction in scores, decreasing −26.4% after week 3 ( P < 0.0001 vs. baseline).
From 1999 to 2015, there was a statistically significant rise in mortality (APC = 6.30; 95% CI, 4.08 to 7.67; P = 0.0036), followed by an even steeper and highly significant increase from 2015 to 2023 (APC = 15.87; 95% CI, 11.85 to 24.98; P < 0.0001), representing the most pronounced regional acceleration in mortality.
The mean differences between the two groups were highly significant ( t = 11.01, p < 0.0001 and t = 7.90, p < 0.0001 for 2016-off and 2016-main seasons, respectively) indicating that SrH confers significant effects on disease severity reduction in addition to conferring a resistant infection response.
Although there is considerable individual variation between prediction and soil data, the fit is highly significant [ p < 0.0001, as discussed in the Supplemental Material ( http://www.ehponline.org/docs/2006/8659/suppl.pdf )].
The difference in TsH values between both groups was highly significant ( P < .0001) as well as between group A and control group ( P < .001; according to the all pairwise multiple comparison procedures-Holm-Sidak method).
In the middle quartiles ( Figure 4 D,E), donepezil-treated aged mice showed highly significant reductions in alveolar size compared to aged controls ( p < 0.0001).
The two-way ANOVA revealed that both factors (i.e., sodium alginate dose and contact time), as well as their interaction, were highly significant ( p < 0.0001) for calcium reduction.
Comparison of normal mucosa, tumor-adjacent mucosa, and tumors disclosed a strong and highly significant (p < 0.0001) up-regulation of EpEX in tumors with median IHC scores of 220 versus 60 and 50 in tumor-adjacent and healthy mucosa, respectively (Fig. 1d ).
However, when studied ex vivo by γ-counting, both monotherapy and combination therapy showed highly significant effects on tracer retention (Supplemental Fig. 3; P < 0.0001 and P = 0.0007, respectively), but there was no difference between treated tumors with and without gemcitabine ( P = 0.9).
Furthermore, Malat1 expression exhibited a 1.46-fold increase compared to the ODM group ( Figure 5 C), which was highly significant ( p < 0.0001).