Excerpts

The effect of combination therapy was highly significant with regard to resistance suppression, as shown in Fig. 3 ( P = 0.0006; Breslow-Gehan test).

Also, the interaction effect of LDL cholesterol changes from a highly significant 13.9 mg/dl ( P = 0.0006) to a marginally nonsignificant 5.7 mg/dl ( P = 0.076).

Following perfusion of the CB1R-specific inverse agonist LY320135 , there was a marked reduction in normalised gamma power to 39.4 ± 10.1% of control, and this was highly significant ( P ≤ .0006, n = 9).

Effect of treatment, landscape diversity, and prairie vegetation on the bee community Regression analyses with the presence or absence of prairie strips and Shannon landscape diversity as independent variables indicated that strip treatment had a highly significant effect on the abundance of all bees ( Fig 3a and S6 Table ; p = 0.0006), 8 common bees ( Fig 3b ; p = 0.0014), 9 common bees ( Fig 3c ; p = 0.0022), and uncommon bees ( Fig 3d ; p = 0.0002).

Nevertheless, the recording-first group showed quantitatively greater improvement while improvement in the quote-first group was only borderline significant (recording-first improvement = 1.29, t 51 = 3.67, p < 0.0006, d = 0.49; quote-first improvement = 0.59, t 43 = 1.96, p < 0.057, d = 0.29; Figure 4C ).

Similarly, the Actin signaling pathway achieved a highly significant separation in females ( P = .0006) compared to a weaker association in males.

The pooled estimate remained highly significant (RR = 0.45 [0.29–0.71], p = 0.0006, I 2 = 0%).

All P values were highly significant (highest P value= 0.0006), so any inflation of the type I error due to the lack of adjustment for multiple admissions for the same patient (only 1.43 on average) would not have significantly affected the analysis. 15 Figure 2 shows the scoring system for the point values assigned to each of the predictor variables.

All success rates were highly significant above chance-level (33.3% on a 3-alternative-forced choice; p < 0.0006 (n = 7) for all comparisons, as assessed by a Wilcoxon rank sum test; importantly, this is the lowest p-value possible in this non-parametric test, given the number of subjects.

Thus, the first group showed a clear trend of PMBR increase over learning (linear model fit: F -statistic vs. constant model = 24, p = 0.0006), while the second group showed a clear trend of PMBR decrease over learning ( F vs. constant model = 45.1, p = 0.00005; Figure 2F ).

Differences in survival times of rMVAGnGc were highly significant (χ 2 = 17.48; df = 3; p = 0.0006). 3.3.

In the dominant model, carriers the C allele indicates protection to malaria, carriers of the C allele were compared to individuals with the T allele, and the difference is highly significant (OR 0.52 [95% CI 0.37–0.76]; p = 0.0006).

As expected, all of these findings were accompanied by a highly significant difference in overall survival between the CTC groups (57.9 months for patients with CTCs <5 CTCs/7.5 ml versus 27.3 months for those with ≥5 CTCs/7.5 ml; P = 0.0006).

A moderate/substantial amount of heterogeneity was present ( I 2 = 68%) and test for subgroup differences was highly significant ( χ 2 = 17.41, p = 0.0006, Fig. 4 ).

The chi-squared test showed a very highly significant relationship between clinical and environmental strains and their resistance profile ( P = 0.0006).

The difference was highly significant for total species richness ( χ 2 = 11.921, P = 0.0006) and exclusive species richness ( χ 2 = 42.667, P = 0.0001) but was not significantly different for the richness of plant families ( χ 2 = 1.463, P = 0.2265, Figure 3 ).

The analysis of the trend performed using the Jonckheere-Terpstra test showed a significant trend between the value of pelvic tilt and the values of radial displacement of the belly of muscle for ES (p = 0.00060*), GM (p = 0.00493*), RA (p = 0.00009*) and OAE muscles (0.00015*).

t -Test Results The independent samples t -test revealed a highly significant difference in mean thickness: t(df) = −5.30, p = 0.0006 This confirms that restorations that failed to debond were significantly thicker than those successfully debonded.

Both differences were highly significant ( P = 0.0006 and P < 0.0001, Figure 1 A,B).

The 24‐month LS meta‐analysis with five paired comparisons in 885 adolescents showed a highly significant weighted mean BMD difference of −0.02 (95% CI: −0.03 to −0.01) g/cm 2 in CHC‐exposed adolescents ( P = 0.0006).

T3 concentrations were significantly higher in the eggs laid under the poor food condition and the total T3 content also tended to be higher although this did not reach statistical significance (T3 concentration, P = 0.0006.

Among them, extremely significant differences were present in the body weight traits in adult SWCG ( p = 0.0006).

While no such association was observed for older males, a highly significant sex-specific effect was observed when comparing female with male G -allele carriers ( P = 0.0006).

At day 14, compared to untreated group the two-tailed p values of 46F2SIP and L19-IL2 groups were very significant ( p = 0.0041, p = 0.0047) and for 46F2SIP/L19-IL2 group were extremely significant ( p = 0.0006), indicating the strong efficacy of combined therapy.

Further analyses revealed an extremely significant association between HBsAg and/or anti-HBc seropositivity and the number of blood transfusions ( P = 0.0006) and units ( P = 0.0002) that exclusively ranged up to fifty and sixty transfusions/units, respectively.