There is a clear trend suggesting that diabetes exacerbates cognitive dysfunction in schizophrenia (global cognition: SMD=−0.26; P = 0.1087; 95% CI, −0.59 to 0.08), particularly in domains such as reasoning (SMD=−0.40; P = 0.0109, 95% CI −0.58 to -0.22) and processing speed (SMD=−0.43; P = 0.0005, 95% CI −0.52 to −0.35).
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However, there was a clear trend in the risk of ATE in patients with pre-MF (18.2% vs. 7.8%, p = 0.11).
A clear trend was also demonstrated by mIF imaging for increased intratumoral CD3 + CD8 + PD1 + T cell infiltrates in the T cell-inflamed versus non-T cell-inflamed (p=0.11) or intermediate (p=0.20) UPMC samples ( figure 1D ), further validating the immunophenotypic groups used for downstream analysis.
However, the multivariate analysis in our study showed a clear trend for younger age as a predictor of a moderate–severe MIDAS score (OR 1.09, p = 0.13).
MR): No significant differences were observed in any brain region ( p > 0.05), but there was a clear trend toward enhanced LMC activation (M = 1.177 ± 2.728, t = 1.613, p = 0.131).
Although there was a clear trend towards fewer complications in the UBE group, the difference in total incidence between the 2 groups did not reach statistical significance ( P =0.14).
Regarding TFC, there was a clear trend toward faster functional decline in CAG-CCG LOI patients, although it did not reach statistical significance ( p = 0.146) ( Figure 4 ).
For the expression of ER-alpha, a significant result was also observed that the TFP group in reference samples was greater than the TFN group with a clear trend (one-sided Wilcoxon rank-sum, ESR1|ER-alpha, p = 0.15; ESR1|ER-alpha_pS118, p = 0.05, Fig. 3 C).
Significant astigmatism (≤ −0.75 D) does not show a clear trend over time, with no significant association observed (χ 2 statistic = 8.907, P = 0.167).
The gm-PBM treatment group showed a clear trend toward improvement in entry frequency (3.8 ± 1.48 times); although the difference did not reach statistical significance versus the AD group ( p = 0.18), the numerical increase may hold biological relevance.
Although significance was still not reached, the result revealed a clear trend toward inferior DFS among patients with elevated RPMB levels (HR = 1.585, 95% Cl: 0.781–3.215, p = 0.2, Figure 4C ).
Although not significant there was a clear trend in the association between HHV-6A and HHV-6B [OR: 5.04 (0.53–247.07); P = 0.20, Figure 1C ], the lack of significance was probably due to the very low incidence of HHV-6B reactivation.
CD79B Y196 mutation also showed a clear trend toward better PFS and OS, although the difference was not statistically significant (PFS: HR = 0.54 [95% CI, 0.18 – 1.69], p = 0.228, OS: HR = 0.27 [95% CI, 0.08 – 0.95], p = 0.064) (Figure S3 ). 3.4 Rapid genotyping of MYD88 L265P and CD79B Y196 mutations by i‐densy We suggest that CD79B Y196 mutation is not only a reliable diagnostic marker combined with MYD88 L265P mutation but also a predictive factor for response to R‐MPV.
In the high-cytogenetic-risk group, although there was a clear trend favoring group 1, the OS difference was not statistically significant—1068 days for group 1, compared to 693 days in group 2 ( p = 0.246) ( Figure 10 ).
A clear trend was detected showing higher GPC for the T allele of TDsat2.i1.1 ( Supplementary Figure 8 , Supplementary Table 2 ; P-value = 0.30).The A-allele of the KASP marker TDsat2.e9.1 was greatly underrepresented; thus, its effect cannot be assessed using this panel. 3.4 sat2 is predominantly expressed in grains Comparative transcriptomics approaches are crucial in transferring biological information, particularly conserved gene functions from better-studied species ( Zuluaga et al., 2023 ).
Successful mechanical resynchronization after CRT-P implantation was demonstrated by a clear trend towards reduction in SPWMD from 153.3 ± 94.5 ms to 53.3 ± 15.3 ms (n = 3; p = 0.32; Figure 6D ), as well as a trend towards reduction in LVEMD ( Supplementary Figure S1 ).
Effects of Parental Sequential Herbivory on Nitrogen and Protein Percentage of Progeny Plants Results from cotyledon nitrogen and protein estimation showed that overall nitrogen percentage did not differ significantly across treatments; however, a clear trend was observed (Figure 3a,b ; p = 0.367, p = 0.344).
Partial Pressure and Production of N 2 O Additions of both salts did not produce a clear trend in N 2 O production with increased salinity ( p = 0.44).
Additionally, the mobility parameter in male NM does not appear to follow a clear trend, with there being no significant difference between controls of NC grade 2 (68 yo) and NC grade 3 (73 yo) ( p = 0.453542).
The linear effect was significant ( p = 0.006), indicating a clear trend of decreasing corticosterone with lower CP levels, while the quadratic effect was not significant ( p = 0.524).
There was a clear trend suggesting Occludin decreases at 6 and 24 hours, however, it did not reach significance (p = 0.87 and p = 0.92), whereas reduction in the Occludin levels at 12 hours was statistically significant (ZO-1 ipsilateral hemispheres: Ctrl: 146.11 ± 39.8%, 1 h: 106.1 ± 47.2%, 3 h: 115.3 ± 34.6%; 6 h: 51.2 ± 22.4%, 12 h: 37.2 ± 15.3%, 24 h: 44.3 ± 19.6%; Occludin ipsilateral hemispheres: Ctrl: 130.8 ± 32.5%, 1 h: 99.9 ± 61.3%, 3 h: 109.4 ± 53.1%; 6 h: 46.8 ± 40.0%, 12 h: 28.8 ± 12.7%, 24 h: 47.3 ± 32.4%) ( Figure 4(a) to (c) ).
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a clear trendgold
The PCA score plots in Figure 5a shows a clear trend of separation between the hippocampal tissues of rats in the L and DM groups, with R2X (cum) = 0.598.
a clear trendgold
Plotting nitrate concentration against sulfate concentration, as displayed in Figure S20 , shows no clear correlation, but when the nitrate concentration is plotted against the ammonium to sulfate mole ratio for individual days, a clear trend is revealed.
a clear trendgold
Conclusions Despite the limitations of the study, analysis of the available data showed a clear trend.