In the first 3 years of AP, the risk of PC increased significantly with time (OR 29.13, 95% CI : 16.34-51.93), and a decreasing trend after 3 years, with no significant association between AP and PC risk beyond 10 years (OR 0.88, 95% CI: 0.35-2.22, P > .05).
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Interestingly, MYPT1 protein expression in PCa tissues displayed a decreasing trend depend on the increasing Gleason scores ( P < 0.05, Fig. 4c ) and the presence of BCR ( P < 0.05, Fig. 4c ).
The viability of neurons and SH-SY5Y cells exhibited a decreasing trend that was not significantly different ( p > 0.05) after incubation with 50 μM ferrous chloride.
The relative abundance of Proteobacteria showed a decreasing trend in the n -3 PUFA and n -6 PUFA groups compared to the HSR group ( p > 0.05), but it was still higher than that in the control group ( p < 0.05).
When treated with increasing concentrations of Ang II, miR-34a levels showed a decreasing trend at 24 h treatment but at 48 h and 2 μM concentration its levels augmented (1.63-fold increase, p < 0.05) ( Figure 4 C).
The functional parameter of intracellular ROS production showed a decreasing trend with each subsequent evaluation, the difference being significant (p<0.05) at fourth evaluation in comparison to first evaluation.
Compared to the control, apical dendritic path length showed a decreasing trend in the IR ( p < 0.05), malathion ( p < 0.05), and coexposure ( p < 0.01) groups (Fig. 2 c).
Conversely, hospital visits showed a decreasing trend from lag0 (RR, 1.02; 95% CI, 0.92-1.23) to lag5 (RR, 0.72; 95% CI, 0.65-0.80; p<0.05) for misty days, and there was a significantly lower number of hospital visits at lag5 for foggy days (RR, 0.85; 95% CI, 0.75-0.97; p<0.05).
Annual WUE exhibited a decreasing trend for shrublands (p < 0.05), an increasing trend for deciduous broadleaf forests (p < 0.05), and no significant trends for other vegetation types ( Fig.
Interestingly, regardless of radiation type and dose, we found a decreasing trend for H3K27ac ( p < 0.05), an increasing one for H3K9me3 ( p < 0.05) and no trend for H3K4me3 and H3K27me3 ( p > 0.05; Fig. 3 C; data shown for 56 Fe 1 Gy).
Resource Variation Over the Experiments In both ecosystems, TDP followed a decreasing trend over time (RM-ANOVA, effect time p<0.05, Table S1 ) with a steeper decline in the P-added treatments ( Figure 1A, B ) while concentration of TDN did not change (RM-ANOVA, time effect p-value>0.05).
Concerning the central aspect of fatigue, the SMM did not induce change in %VA for PF ( P = 0.73), but a decreasing trend was observed for KE (−2.18±2.96%, P = 0.05, d = 0.96).
The E 2 level, on the other hand, had a gradual increase from Day 7 to Day 18 after which it showed a decreasing trend (P < 0.05) (Figure 1B ).
Compared with starting levels (122.9 ± 3.2 mEq/L (mean ± SEM)), sweat chloride showed a decreasing trend over time, with a significant difference at six months ( p < 0.05), while BMI and FEV 1 % increased in time, although only by trend.
Additionally, in PCOS rats, spleen weight exhibited a decreasing trend without statistical significance (ANOVA, P > 0.05), whereas the spleen index was significantly reduced (ANOVA, P < 0.05), suggesting impaired systemic immune function.
Compared with the Control group, the Model group exhibited significantly elevated levels of TG, TC, and LDL-C in both serum and liver tissue ( p < 0.001), while serum HDL-C levels showed a decreasing trend without statistical significance ( p > 0.05).
A total of 10 ARGs types exhibited a decreasing trend, among which 6 ARGs types were significantly decreased, including beta-lactam ( P < 0.05, R 2 = 0.61), MLS ( P < 0.05, R 2 = 0.53), quinolone ( P < 0.01, R 2 = 0.84) and tetracycline ( P < 0.05, R 2 = 0.64) (Fig. 5a ).
2a ); CD4+ T cells (key immune helper and regulatory cells) exhibited a decreasing trend, albeit without reaching statistical significance ( P > 0.05), CD8+ T cells (core effector cells that directly kill tumor cells) were significantly increased ( P < 0.001, Fig. 2b ); leading to a significantly decreased CD4+/CD8+ T cell ratio ( P < 0.001, Fig. 2k ); also B cells (core cells of humoral immunity responsible for antibody production) were significantly downregulated ( P < 0.01, Fig. 2c ).
Although the CSA of the LSR+PDRN group showed a decreasing trend, there was no significant difference in the CSA between the LSR+PDRN and LSR groups at week 6 ( P > 0.05).
However, a decreasing trend in P 21 values ( p > 0.05) was observed in the case of Formulation 3.
Similarly, total carboxylic acids increased at 6 days ( p < 0.05) and decreased at 14 days, showing higher values than the first aging day ( p < 0.05).Pyrazine, methyl- showed a decreasing trend with lowest values at 9 aging days ( p < 0.05).
RT-qPCR analysis revealed that CXCL-8 mRNA expression was significantly downregulated in Ninj1-silenced HUVECs compared to control cells (p=0.016), while TNFAIP3 and CXCL-1 mRNA levels showed a decreasing trend without statistical significance (p>0.05) ( Figures 4A–C ).
Gestational age at delivery differed significantly across PPBMI groups ( p < 0.05), with a decreasing trend observed in higher PPBMI categories; Neonatal birthweight differed significantly across PPBMI groups ( p < 0.05), showing a positive trend with higher PPBMI.
For example, GM1 significantly increased from premenopause to transition group (p < 0.05), while SiE showed a decreasing trend from transition to postmenopause group (p < 0.05) ( Table 3 ).
A decreasing trend in lung cancer burden (incidence and mortality) was associated with improved PHD scores and lower genetic risk ( P < 0.05) [ 59 ].