“a significant trend”

When we grouped the patients according to their genotype and S-MBL above or below the median for their genotype (high/above [ n = 78], high/below [ n = 78], low/above [ n = 65], and low/below [ n = 66]), there was a significant trend among the four groups to predict survival free from cardiovascular event (log-rank test P = 0.01) ( Fig. 1 ).

If a significant trend was detected at p ≤ 0.01, Williams’ test was used [ 21 ]; if the trend was not significant Dunnett’s test was used [ 22 ].

For 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) a significant trend (p = 0.01) for the SMRs with increasing cumulative PCDD/F exposure was observed.

However, a significant trend of higher LN count and higher likelihood of liver metastases was observed ( P = 0.010).

Although there was a significant trend ( P <0.01), reduction of CRC risk did not appear to be stronger with duration of HRT use.

Compared with the latter, our cohort presented increased mutation frequency of DUSP2 , BTG2 , IRF4 , MEF2B , MYC , CD79B , BCL7A , NFKBIE , FAS , and CIITA ( p < 0.05), with a significant trend toward changes in TP53 , CCND3 , CD58 , and CXCR4 ( p < 0.01).

Experimental mice on HFD exhibited a significant trend of weight gain compared with WT mice fed on ND and HFD ( p < 0.01, ApoE −/− /HFD vs.

Similarly, there was a significant trend in all item scores (with the exception of environmental autonomy) across the cognitive subgroups (all p<0.01).

At the seasonal level, we found a significant trend in NEE only in autumn, which indicated that the forest's net C sink increased during autumn over the 26 years of the study ( p < 0.01; Table 1 ). 3.2 Trends in Daily NEE Fluxes Over Time To assess the effects of climate change on NEE throughout the study period, we analyzed the days with the strongest net C uptake, that is, 1st, 5th percentiles of NEE c,DOY , and strongest net C loss, that is, 95th and 99th percentiles of NEE c,DOY , as well as the median NEE c,DOY during the 26‐year period (Figure S4 ).

We found a significant trend in the unadjusted relative risk of death from total CVD, IHD, and stroke (all P <0.01 for linear trend) (Table 3 ).

In the low risk group the preterm proportion was highest in the most deprived quintile (1.6% CI 95 1.4 to 1.8) with a significant trend towards a higher proportion of preterm births as deprivation increases (Chi square for trend p<0.01).

The current study results consistently demonstrated a significant trend ( P < 0.01).

Mortality showed a significant trend towards benefit in the case of transradial primary PCI {2.04% vs. 3.06%, OR 0.54 (95% CI 0.33-0.86), p=0.01}.

We also found no significant interaction on the log-odds scale between PGSs and individual rCNVs, except for the 16p13.11 duplication and ADHD-PGS (β = −0.51; 95% CI, −0.86 to −0.16; P = .006), although, there was a significant trend for negative interaction coefficients (27 of 39; P = .01 in a binomial test) (eTables 11 and 12 in Supplement 2 and eTables 13 and 14 in Supplement 1 ).

2 a ) further supported a significant trend toward higher ω values (indicative of relaxation of selection) in lungfish (Mann–Whitney U test, P < 0.01).

After LPS stimulation, the macrophage supernatant co-cultured MSCs in the hydrogel groups showed a significant trend of ALP formation, among which the bone activity of the hydrogel containing TA@Ag NPs was the most significant ( Fig. 4 c, p < 0.01), and the early osteogenic activity of LPS + MФ+HA-DA/Alg-PBA/TA@Ag NPs hydrogel group was enhanced by 56.74 times compared with that of the LPS + MФ group.

1 A) revealed a significant trend for all-cause mortality among GOLD stages ( P < 0.01 for trend).

Comparison of the distribution of SCAI Shock stages revealed a significant trend towards a higher proportion of stages D (58.9% vs. 47.2%) and E (1.8% vs. 0.4%) ( P = 0.01) among the 1‐year non‐survivors.

Poisson regression analysis, stratified by period (pre-lockdown, during lockdown, and post-lockdown), revealed a significant trend toward an increase in cardiac arrest incidence (rate ratio: 8.31; CI: 8.28–8.34; p < 0.01).

Comparison of the distribution of SCAI SHOCK stages revealed a significant trend towards a higher proportion of stages D (64.7% vs. 25.0%, P < 0.01) among the 1‐year non‐survivors.

There was a significant trend for TN specimens to accumulate more Cu relatively to Zn, as shown by the negative [Zn | Cu] balance difference (TP–TN) ( p < 0.01).

There was a significant trend for White patients to be more readily offered CAR-T than their non-White counterparts (offered CAR-T: 29% vs 6%; P <0.01), with BsAbs also more likely offered to White patients (offered BsAbs: 21% vs 8%; P =0.096).

However, among kidney transplant patients younger than 50 years at the time of transplantation ( n = 754), there was a significant trend for increasing the occurrence of post-transplant CV complications along the consecutive KDRI quartiles (χ 2 = 7.3; p < 0.01), with the frequency of CVEs across the study groups as follows: Q1 13/205, Q2 23/179, Q3 24/166, and Q4 21/123.

There is a significant trend (P = 0.01) in which cuticle thickness generally increases with increasing length of time to knock-down, although the correlation is weak (R 2 = 0.33).

The fully adjusted model demonstrated a significant trend correlating increased TTHC (P<0.01 for trend), SR (P<0.001 for trend), and Ki-67 expression (P=0.004 for trend) with ALNM.