“a significant trend”

Fewer alterations were found in patients with metaplasia alone and there was a significant trend towards a higher frequency of alterations with increasing histologic grade (p = 0.009).

There was a significant trend of increasing risk of hypertension in corresponding to increasing level of urinary MMA concentration ( p = 0.009).

This analysis showed that, in patients with CHD, the relationship with reduced eGFR was different between people with diabetes and those without, in whom a significant trend of increase in ORs from higher to lower eGFR was observed ( r 2 = 0.92, P = 0.009) ( Figure 1 ).

When analyzed by quartiles, a significant trend emerged (OR: 0.85 per quartile increase, 95% CI: 0.75-0.96, P=0.009).

Similarly, a significant trend towards better outcomes was observed with increasing Kawaguchi scores ( p = 0.009), with grade 1 tumors having a 51.7% lower probability of good outcomes compared to grade 3 ( Figure 4 and Figure 5 ).

There was a significant trend for higher prevalence of central obesity among those in the lower occupation groups (p = 0.009).

However, there was a significant trend towards greater risk of problem drinking among those experiencing varying changes, from a decrease to a rise, in inequality ( p = 0.009).

In addition, meta-regression of serum gastrin elevation ( Figure 4(e) and ( f )) revealed a significant positive correlation with both treatment duration and vonoprazan dosage, where longer therapy was associated with greater gastrin elevation compared with lansoprazole (coefficient = 1.7972 per week, p < 0.0001) and higher vonoprazan doses showed a significant trend toward increased gastrin levels (coefficient = 9.3422 per mg, p = 0.0093).

Indeed, there was a significant trend in increasing absolute cortical thickness from sulcal to intermediate to gyral cortices (rank correlation of individual values ρ = 0.56, p < 0.01; sulcal average: 1,747 ± 112 μm; intermediate average: 1,791 ± 90 μm; and gyral average: 2,227 ± 132 μm), confirming quantitatively previous qualitative observations [ 9 ].

There was a significant trend (Armitage trend test p < 0.01) of decreasing IFI incidence with increasing GA, falling from 4.6% at 22–23 weeks GA to 0.2% at 28 weeks GA ( Figure 3 ).

In terms of lung cancer, sensitivity analysis using adjusted estimates only showed a significant trend towards a higher incidence of lung cancer among HF patients [HR, 1.68 (95% CI: 1.13–2.49), P = 0.01] (see Supplementary material online , Figure S9 ).

From the pooled data we derive that the overall force/CSA is higher among the C57BL/10 mice compared to mdx (ANOVA, p < 0.01) independent of temperature, and there is a significant trend toward increasing force with increasing temperature (ANOVA, p < 0.01) for the overall data set.

For 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) a significant trend (p = 0.01) for the SMRs with increasing cumulative PCDD/F exposure was observed.

Compared to controls, S-losers had significantly lower plasma anti-HBc levels prior to HBsAg seroclearance, with a significant trend of declining plasma anti-HBc 8–5 years prior to HBsAg seroclearance (p < 0.01), while such trend was not observed in controls.

In the treatment-group, there was a significant trend of lower levels of proinflammatory cytokine interleukin (IL)-2 during 6-hour adsorption compared to the control group ( P = .01).

A significant trend towards increased AZM resistance over time was observed (R 2 =0.32, P <0.01; Fig.

It is worth noting that the Pielou evenness index showed a significant trend of first decreasing and then increasing with increasing longitude ( p < 0.01) (Figure 3c ).

[ 63 ], conducted a case-control study in the USA and found a significant trend for increased breast cancer risk in post-menopausal women exposed to high PAH levels at birth ( P = 0.01), with ORs ranging from 1.94 to 2.42, suggesting a dose-response relationship.

Hospital-based primary care providers had the highest proportion of participants who felt care had improved (80.9%), whereas two-thirds of COPC participants (67.1%) and half (50.0%) of Consortium participants did so, representing a significant trend (Spearman’s rho, p ≤ 0.01).

A significant trend of decreasing willingness to accept treatment with increasing educational attainment was observed (p < 0.01, following adjustment for price, gender, age, and experience with heart disease) (Table 2 ).

OxLDL significantly reduced MMP integrity, while NAC treatment restored mitochondrial polarization showing a significant trend with increasing doses ( p < 0.01).

Experimental mice on HFD exhibited a significant trend of weight gain compared with WT mice fed on ND and HFD ( p < 0.01, ApoE −/− /HFD vs.

Results Temperature, lake level, precipitation and cyanobacteria bloom The 30-year data set of continuous epilimnetic temperature records in Lake Maggiore shows a significant trend (Mann-Kendall/Two tailed trend test, n: 346, p<0.01) toward warming ( Fig. 2 ).

If a significant trend was detected at p ≤ 0.01, Williams’ test was used [ 21 ]; if the trend was not significant Dunnett’s test was used [ 22 ].

Relative to census tracts with the lowest levels, we observed significantly increased rates of all leukemia among census tracts with the highest levels of ambient 1,3-butadiene (RR = 1.40; 95% CI, 1.07–1.81) as well as a significant trend ( p = 0.01) ( Table 4 ).