Barely Significant
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a trend toward significance

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a trend toward significancep = 0.0811.6× alpha
Predictors of NIHSS-Shift In the multivariable linear regression model, IVT was associated with a favorable NIHSS-shift, showing a trend toward significance (β = −17.53, p = 0.081), consistent with the matched analysis.
a trend toward significancep = 0.0811.6× alpha
The interaction test between VEGF -1498 C/T variants and treatment effect, including both bevacizumab-group and control group, suggested that the relation of VEGF -1498 T/T genotype with poor outcome was significantly associated with the effect of bevacizumab in terms of PFS (p = 0.011) and with a trend toward significance with regard to OS (p = 0.081) (Table 5 ).
a trend toward significancep = 0.0821.6× alpha
Alpha Diversity Between Clusters The measurement of alpha diversity OS (observed OTUs) showed a difference ( p = 0.04) between clusters, and Chao1 indicated a trend toward significance ( p = 0.082), suggesting that Cluster 1 had less diversity and Cluster 2 had higher diversity ( Figure 4 ).
a trend toward significancep =0.0821.6× alpha
However, there was a trend toward significance on depression severity assessed on the Montgomery–Åsberg Depression Rating Scale (MADRS) ( p =0.082), with the citalopram group showing a bigger reduction in MADRS. 15 O’Connor et al., who conducted a larger study ( n =469) on 12-week sertraline treatment also found no difference compared to placeb