Barely Significant
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a trend toward significance

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a trend toward significancep = 0.08351.7× alpha
Results Behavioral tests Open field test (OF) and elevated plus maze (EPM) For the time spent in the center of the OF, 2-way ANOVA revealed a significant main effect for FS [ F (1,50) = 11.91, p = 0.0011], and a trend toward significance for ELS [ F (1,50) = 3.118, p = 0.0835] as well as for interaction [ F (1,50) = 3.322, p = 0.0743].
a trend toward significancep = 0.08371.7× alpha
Although the action potential threshold was unaffected by iTBS ( Figure 8L , t = 0.5229, d f = 20, p = 0.6068), iTBS significantly increased the maximal rise slope ( Figure 8M , t = 3.398, d f = 20, p = 0.0029), spike amplitude ( Figure 8N , t = 3.054, d f = 20, p = 0.0063), peak ( Figure 8O , t = 2.962, d f = 20, p = 0.0077), with concomitant reduction in afterhyperpolarization amplitude ( Figure 8R , t = 2.209, d f = 20, p = 0.0390), while the maximal decay slope showed a trend toward significance ( Figure 8P , t = 1.820, d f = 20, p = 0.0837). 3.11 Prolonged iTBS produces long-lasting after-effects that possibly facilitate maturation and stabilization of immature synapses To evaluate whether prolonged iTBS600 produces any lasting after-effects, we performed a preliminary study on isolated synaptosomes at 7- (7 dps) and 14 (14 dps) days after last stimulation.
a trend toward significancep = 0.0841.7× alpha
Mean rigidity scores decreased slightly (–0.50 points), bradykinesia showed a moderate reduction (–0.54 points, dz = –0.55) with a trend toward significance ( p = 0.084), and rest tremor was reduced by half (–0.75 points, dz = –0.49), though without reaching statistical significance.
a trend toward significancep = 0.08471.7× alpha
In the open field test (OFT, Figure 1 Biii), no significant between-group differences were observed in total distance travelled, time in the arena centre nor the frequency of rearing, digging or grooming over the course of the study (although Chow-P results were universally higher than Chow-C after 24 weeks supplementation with a trend toward significance for digging: 84.8%, p = 0.0847).