In addition, we found evidence of high GNA12 expression in multiple sets of colorectal RNA-seq data ( GSE107593 : P = 7.48 × 10 −9 , LogFC = 0.42; GSE117993 : P = 6.76 × 10 −7 , LogFC = 0.27; GSE166925 : P = 1.09 × 10 −3 , LogFC = 0.52) and suggested an elevated trend in myeloid cells ( GSE162335 : P = 3.71 × 10 −13 , LogFC = 0.42).
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Further analysis showed that expression of MerTK in both CD56 dim and CD56 bright NK cells had an elevated trend in SLEs when compared with HCs (CD56 dim : 209.8 (90.9–557.3, p<0.001 vs 70.4 (47.5–156.3); CD56 bright : 419.3 (143.4–5905, p=0.040 vs 198.3 (108.0–607.1)) ( figure 1E ).
The expression of CD34 mRNA in caput epididymis tissues of yaks compared to corpus and cauda showed an elevated trend ( p < 0.01).
The results showed that the expression of c-kit mRNA and SCF mRNA in the tail-hanging group was significantly lower compared with that in the control group ( P < 0.0001; P < 0.001), and the expression of c-kit mRNA and SCF mRNA in the tail-hanging group presented a trend of elevation with significant difference ( P < 0.01), and that in the tail-hanging group the expression of SCF mRNA in the probiotics The expression of SCF mRNA in the tail-hanging group showed an elevated trend with significant difference ( P < 0.01), The expression of c-kit mRNA in the probiotic tail-hanging group showed an elevated trend, but there was no significant difference ( P > 0.05; Figure 2 ).
Lymphocyte subset monitoring showed an increasing trend in CD8+ T and B cells after CIK cell therapy ( P > 0.05) and an elevated trend in NK cells after NK cell therapy ( P > 0.05).
Notably, Pg application did not significantly increase the proportions of B/plasma cells or macrophages ( p > 0.05), and neutrophils showed an elevated trend with no statistical significance ( p > 0.05) ( Figure 5 D).
Fluorescence imaging revealed an elevated trend in hepatocyte apoptosis within the 2,4-D group compared to control animals, although this difference did not reach statistical significance ( p > 0.05).
While PC3 showed an elevated trend in ASD-only (Cohen’s d = 0.195) ( Figure 12c ), it remained non-significant (p > 0.05).
Compared to those in the CON group, lactating cows in the trial groups showed an elevated trend in all the indicators except for non-fat milk solids and ash, although treatment, linear, and quadratic differences were not observed ( p > 0.05). 3.3.
Adenine intake activated the oxidative stress Compared with the NC group, MDA level of kidney tissues in the NML group showed an elevated trend ( P > 0.05), while in the NMM and NMH groups was considerably higher ( P < 0.05; P < 0.05) ( Fig. 3 F).
HD group showed an elevated trend p = 0.0706.
Similarly, the patients with PH‐HFrEF with increased PAWP also showed an elevated trend of E/e′ (increased PAWP vs. decreased PAWP: 17.8 ± 5.9 vs. 13.9 ± 3.8, P = 0.08).
The whole SN lysates of human PDs display an elevated trend of H4K12ac accumulation compared to age-matched controls ( n = 12, p -value = 0.099) ( Figures 4A , B ).
With regards to live birth rates, an elevated trend was observed as 26.2% vs. 19.9% [RR 1.32 (0.93-1.87)] compared with the placebo arm, without statistical significance (P=0.122).
Although BHR degree, which was reflected by PD 20 , did not differ between the two groups, it showed an elevated trend in the CA group ( p = 0.231).
While baseline LUS aeration scores showed an elevated trend in the transfer group (12 vs. 10), the statistical difference was not significant ( P = 0.242).
In addition, the DCR exhibited an elevated trend (lacking statistical significance) in the PD-1 inhibitor + chemotherapy group compared with that in the standard treatment group (81.0 vs. 70.0%, P=0.377; Fig. 1 ).
After multivariate adjustment, the extreme group had a significantly increased risk of LGA (aOR = 13.95, 95% CI: 3.21–60.64, P < 0.001); although the marginal group showed an elevated trend (aOR = 2.03), it was not statistically significant (P = 0.522).
We observed HLA‐E and CD19 exhibit an elevated trend, while PVR, CD276, and CD47 are reduced in the low TROAP expression group (Figure 5A ).
Meanwhile, lipid levels in children and adolescents also showed an elevated trend.
The spatial distribution of CD8 + T and CD8 + CD127 + T cells with CD4 + T/CD20 + B cells showed an elevated trend in MPR patients in both NAC and NAPC, whereas CD8 + KLRG1 + T cells exhibited an elevated trend in non-MPR patients in the NAPC group (Supplementary Fig. 8a–f ), which requires a larger cohort to verify.
Although the protein levels for the adipogenic markers PPARG, FABP4 (both not significant) and PLIN1 (significant) showed an elevated trend for shRNA1 as well, only the effects of shRNA2 on Oil Red O staining were supported by significant changes of the adipogenic markers at protein (Fig. 3 C–D) and mRNA level (Fig.
Although Mat-IL-37 also showed an elevated trend in the cytoplasm, the most significant elevation occurred at 6–12 h and started to decrease after 12 h ( Figure 3A ).
Basic studies have shown that the glucose uptake and utilization increased on the first day after TAC operation in HF mice, and showed an elevated trend with time [83] .
In our study, the depression and anxiety scores were significantly higher in the TD and MDD groups, and the depression scores in the T2DM group showed an elevated trend compared with the HC group, which was consistent with the results of the previous study.