Barely Significant
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“an increasing trend”

63,972 sentences · 63,972 papers · 107,686 search hits before verification · confirmed specimen

Sighted at

p<0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

In general, the initial visual acuity remained almost stable or showed an increasing trend but still remained below the lowest limit of the age-standardized BCVA ( Supplementary Table S2 ); this progression exceeds the typical age-related vision improvement, potentially confirming the degenerative nature of RP2 -associated XLRP.
In Malaysia, the National Surveillance of Antibiotic Resistance (NSAR) report indicated that both meropenem and imipenem showed an increasing trend in resistance until around 2014–2015, after which the resistance gradually declined up to 2018 [ 7 ].
Temporal trends in age-standardized rates were quantified using Joinpoint Regression Program (version 5.1.0.0; National Cancer Institute, USA), with annual percentage change (APC) and average annual percentage change (AAPC) reported alongside 95% confidence intervals (CIs); an AAPC >0 indicates an increasing trend and <0 a decreasing trend.
Notably, a large-scale historical cohort study of Israeli diabetic patients ( n = 145,617) revealed through analysis with advanced statistical models that the association between metformin exposure levels and prostate cancer risk is not fixed but may exhibit dynamic characteristics: short-term exposure (in the first year) even showed an increasing trend in risk, whereas long-term exposure (2–7 years) exhibited a potential protective effect, with an overall inconsistent association [ 26 ].