Barely Significant
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“did not reach statistical significance”

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did not reach statistical significancep = 0.071.4× alphaplainly factual
Although there was a slight trend towards a higher oral apparent clearance normalized to body surface area in Asian patients (median [range] 89.4 [25–250] l/h/m 2 ) compared with European patients (median [range] 76.7 [26–235] l/h/m 2 ), this trend did not reach statistical significance ( p = 0.07; Fig. 1 a).
18 19 Using PET, a study of 10 controls and 22 patients with CKD stages 3–5 showed a trend towards reduced CFR with increasing stage of CKD, but this did not reach statistical significance. 20 Similarly, retrospective calculation of CFR using PET in 435 patients with stages 1–3 CKD also found there was no significant difference in CFR after correction for cardiovascular risk factors such as age, sex and blood pressure. 21 The largest PET study to date is a retrospective analysis of 3946 patients who underwent stress PET at a single US institution.