The Kaplan-Meier cumulative survival curve in S1 Fig show that compared with nonpruritic patients, those with pruritus showed a trend of lower event-free survival, but the difference did not reach statistical significance ( P = 0.38).
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At 1 μM, Ecz and Mcz showed a trend toward restored reduction but did not reach statistical significance (Fig. 2A ).
a positive trendgold
There was also a positive trend between PMTCT coverage and patient satisfaction; however, this did not reach statistical significance (p = 0.06)[ 31 ].
As shown in Figure 2 , one-way ANOVA followed by Newman–Keuls post hoc tests revealed that PN17 rat mPFC had a significantly higher level of c-Fos ( F (2,20) = 4.36; P = 0.027) compared to adult rats ( P < 0.05) with a decreasing trend from PN17 to PN24 and an even stronger decreasing trend from PN24 to adult age, both of which, however, did not reach statistical significance ( P > 0.05) ( Fig. 2 ).
A recent observational study on acetylsalicylic acid use and iFOBT performance showed a trend towards an increase in sensitivity (from 51.2 to 66.7%) without loss of specificity in acetylsalicylic acid or NSAID users, but the difference did not reach statistical significance, likely due to a relatively low number of acetylsalicylic acid/NSAID users [ 20 ].
Klhl2 in CA1 pyramidal neurons did not reach statistical significance ( p = 0.07) but showed an increasing trend which is consistent with the Drop-seq data.
Relative to the non-targeting control (NTC), stable knockdown of DVL-1 in MCF7 cells showed a trend of higher E 2 production, although this did not reach statistical significance.
Atr +/− B cells also showed a trend toward reduced CSR at days 3 and 4, but the data did not reach statistical significance when compared to either Atr +/+ or Atr +/KD B cells (Fig. 2c ).
Incubation with HIG showed a trend towards efficacy, but did not reach statistical significance for the median percentage of HCMV-positive cells.
On the other hand, after Ang II treatment, Apelin KO mice showed a trend of decreased expression of ACE2 in the heart, but this did not reach statistical significance ( Figure 2 B).
A numerical trend for higher 30-day mortality with TAVI compared with medical therapy did not reach statistical significance, neither in the individual studies nor in random-effects meta-analysis (8.0% versus 4.8%; RR 1.66; 95% CI 0.90 to 3.08; I 2 = 0%).
Despite a clear trend for a protective effect, the association between inhibition of in vitro sporozoite gliding motility and time to falciparum infection also did not reach statistical significance after adjustment for blood-stage immunity (hazard ratio, 0.55; 95% CI, 0.29–1.01).
The level of tau phosphorylated at Ser 202 /Thr 205 by antibody AT8 and at Thr 205 by a polyclonal antibody also showed a trend of increase in ipsilateral hippocampus which did not reach statistical significance (Fig. 4A,B ).
The TXA treatment group showed a trend toward lower blood transfusion rates over the peri- and postoperative period, though it did not reach statistical significance.
SARM1 +/− mice showed a trend toward acceleration that did not reach statistical significance (median survival, 171 dpi; Fig. 2 C ).
Despite a clear trend, tumor grade did not reach statistical significance ( Figure 1 E).
Further analysis with either anti-CD20- or anti-HER2-coated beads showed a trend for more rosettes and thus better binding with IgA compared to IgG, but this did not reach statistical significance ( Figures 3F,G ).
A positive trend occurred in other parameters of the muscular endurance in TCC but did not reach statistical significance.
Conversely, PDIA6 overexpression showed a trend towards decreased apoptosis in A549 cells, although this did not reach statistical significance (Fig.
Although tissue vg copy number and NAGLU activity level appeared to correlate in most of the tissues, further correlation analysis did not reach statistical significance, though the negative correlation in the spleen approached significance.
The CDVA, PROS, FOSPET and FPR showed a trend toward progressive decline when analyzed across pedigree subgroups with simplex or sporadic cases being the best and X-linked, the worst (Table 3 ); however, apart from PROS, the differences did not reach statistical significance.
Conversely, FH6-8 showed a trend, which did not reach statistical significance, toward a reduction in RBC adhesion ( Figure 3B ).
Overall, survival analyses showed a trend toward better OS for HPV-positive (67% survival) compared to HPV-negative (27% survival) patients but that did not reach statistical significance ( p = 0.12), most probably due to the small number of HPV-positive cases ( Figure 4 A). 2.3. p16Ink4a Protein Immunohistochemical (IHC) Staining In view of the small number of HPV-positive HNSCC patients found in this cohort, and the limited amount of pathological materials available, a subset of 50 representative specimens were processed for p16 protein IHC staining.
a slight trendgold
Although there was a slight trend towards a higher oral apparent clearance normalized to body surface area in Asian patients (median [range] 89.4 [25–250] l/h/m 2 ) compared with European patients (median [range] 76.7 [26–235] l/h/m 2 ), this trend did not reach statistical significance ( p = 0.07; Fig. 1 a).
Stim showed a trend for more SWA in ON intervals compared to sham, but the result did not reach statistical significance.