Barely Significant
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“did not reach statistical significance”

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Local accumulations of the cytoskeletal protein neurofilament L in axonal swellings showed a trend towards being more frequent in of KIF5A –/– motor neurons (12.4 ± 5.1 % of cells), in comparison to KIF5A +/– (9.3 ± 1.0 % of cells), and KIF5A +/+ (4.3 ± 4.0 % of cells) motor neurons, but the difference did not reach statistical significance (Fig. 2 ).
RT-PCR analysis of other collagens, in particular Col3a1 and Col5a1 , significantly up-regulated in the Frzb -/- mice compared to wild-type mice in the microarray analysis, depicted a decreasing trend at Day 7 in FRZB overexpressing micro-masses compared to the control micro-masses; however, these comparisons did not reach statistical significance (Figure 4A ).
DN-SCP-MCMV-infected mice treated with IL-18BP alone also succumbed by day 10, but although it did not reach statistical significance, a slight trend toward a better survival up to day 12 was nevertheless observed when the mice received a combination of DOX and IL-18BP (Figure 4 A).
AAV9-mTERT treated mice also showed a trend for an improved glucose uptake and a better homeostatic model assessment (HOMA (Heikkinen et al, 2007 ; Matthews et al, 1985 )) compared to the AAV9-eGFP controls, although differences did not reach statistical significance (Supporting Information Fig S4D and E ).
EA-ONCE/1 (Electroacupuncture Administered Once at PID 1) While EA treatment given only once at PID 1 showed a trend towards reducing tumor-associated nociception when compared to the tumor-no EA groups, this did not reach statistical significance in either male or female animals at any of the time points tested ( Figure 3(a) ).