However, it could not be determined whether this was due to changes in interneurons located in the stratum oriens (Or) or pyramidale (Pyr) as the densities in those subregions showed a trend but did not reach statistical significance ( Fig. 1C ).
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a positive trendgold
A positive trend was observed, with an estimate of 0.0009, but the test did not reach statistical significance ( p = 0.0918).
The age at diagnosis also had a positive trend with height z score, although the p values did not reach statistical significance.
The percentage of oligoastrocytoma in gliomas of the frontal origin (22.5%) showed a trend to be higher than that of non-frontal origin (16.1%), but the difference did not reach statistical significance ( P = 0.066).
However, the changes in these two indices did not reach statistical significance but displayed a decreasing trend in the T1D + NaB group compared with the T1D group (Fig. 3 F, G).
Persons who were in quarantine for a longer duration showed a trend toward higher CES-D scores; however, this difference did not reach statistical significance (mean CES-D of 17.0±14.2 for those in quarantine >10 days versus 11.2±10.1 for those in quarantine <10 days [p = 0.07]).
a strong trendgold
There was a strong trend toward increased fasting plasma insulin levels in MHF offspring, but this difference did not reach statistical significance ( P = 0.068).
Although it did not reach statistical significance, knock down DOK-1 showed a trend of increase in BAL inflammation and airway responsiveness, especially in EPO (+) cells and airway responsiveness at 50 mg/ml methacholine challenge, compared to vehicle-challenged mice ( Figure 2 ).
Local accumulations of the cytoskeletal protein neurofilament L in axonal swellings showed a trend towards being more frequent in of KIF5A –/– motor neurons (12.4 ± 5.1 % of cells), in comparison to KIF5A +/– (9.3 ± 1.0 % of cells), and KIF5A +/+ (4.3 ± 4.0 % of cells) motor neurons, but the difference did not reach statistical significance (Fig. 2 ).
19 Although the improvements in TEWL (transepidermal water loss) and SCH (skin corneum hydration) did not reach statistical significance, a positive trend was observed in the alleviation of subjective symptoms assessed through the SS-10 questionnaire.
While the association between QoL and quality of peer relationships did not reach statistical significance, there was a numerical trend in the expected direction.
The use of VKA showed a trend toward increased risk of bleeding but did not reach statistical significance.
Results also showed a trend toward an inverse correlation of the p16 and EGFR expression that is, p16-positive SCCHN showed less EGFR expression although this did not reach statistical significance ( P : 0.083).
RT-PCR analysis of other collagens, in particular Col3a1 and Col5a1 , significantly up-regulated in the Frzb -/- mice compared to wild-type mice in the microarray analysis, depicted a decreasing trend at Day 7 in FRZB overexpressing micro-masses compared to the control micro-masses; however, these comparisons did not reach statistical significance (Figure 4A ).
Goldstein CA reported a positive trend, with an increase of 1.5 oocytes for every additional hour of sleep, although the correlation did not reach statistical significance [ 29 ].
Thus, although there was a small trend toward increased CD8 T cell infiltration in a peritumoral (‘stalled’) pattern in re-excision samples, this trend did not reach statistical significance.
The primary clinical analysis had a strong positive trend, though it did not reach statistical significance (P=0.2048), and 4/6 clinical endpoints prespecified for hypothesis testing were nominally significant ( Table 1 ).
At 3 months there was a clear trend towards a decrease in pain during activity (-3 mm vs placebo) observed in all three studies although this effect did not reach statistical significance (Fig. 4 ).
DN-SCP-MCMV-infected mice treated with IL-18BP alone also succumbed by day 10, but although it did not reach statistical significance, a slight trend toward a better survival up to day 12 was nevertheless observed when the mice received a combination of DOX and IL-18BP (Figure 4 A).
SNR patterns changes on MPEP+CD did not reach statistical significance, but showed a trend toward increased burstiness, but not as pronounced as LD+CD.
AAV9-mTERT treated mice also showed a trend for an improved glucose uptake and a better homeostatic model assessment (HOMA (Heikkinen et al, 2007 ; Matthews et al, 1985 )) compared to the AAV9-eGFP controls, although differences did not reach statistical significance (Supporting Information Fig S4D and E ).
Although the differences in triglyceride concentrations did not reach statistical significance, there was a statistical trend for increased triglyceride concentration in the obese group (Table 1 ).
EA-ONCE/1 (Electroacupuncture Administered Once at PID 1) While EA treatment given only once at PID 1 showed a trend towards reducing tumor-associated nociception when compared to the tumor-no EA groups, this did not reach statistical significance in either male or female animals at any of the time points tested ( Figure 3(a) ).
After controlling for FIGO stage, the presence of LVSI showed a trend toward worse overall survival although it did not reach statistical significance (HR: 2.16, 95% CI: 0.85–5.45, P = 0.10).
The log-rank test showed a trend towards better overall survival in the high-Bmi-1 group, but it did not reach statistical significance ( p = 0.13, Figure 4A ).