“did not reach statistical significance”

Confirming the latter observation, we detected significant higher frequencies of Cd11b + Ly6G – Lys6C + monocytes in the livers of Tgr5 −/− compared to WT littermates ( Figures 2 E and S2 A), while frequencies of neutrophils (Cd11b + Ly6G + Lys6C − ) in the livers of Tgr5 −/− mice showed a trend toward upregulation but did not reach statistical significance ( Figure S2 B).

The difference between the prednisolone- and placebo-treated groups did not reach statistical significance for the primary outcome (PANSS total score) after 6 weeks, but we observed a statistically significant difference in the PANSS general score and a nonsignificant trend for the PANSS total score at this point.

Although this result did not reach statistical significance, the point estimate supports the possibility of a positive trend.

29 , 85 In contrast to our findings for DBP, although meta-analysis for SBP showed a clear trend for clinically significant decrease with exercise, it did not reach statistical significance.

There was an increasing trend of MMP activity that did not reach statistical significance with addition of sodium nitroprusside 1 μM or 2 μM combined with hydrogen sulfide 40 μM when compared with the hydrogen sulfide 40 μM control.

Although differences did not reach statistical significance, parasympathetic activity, as reflected by RMSSD, showed a trend toward higher values during sleep.

Descriptive data showed that treatment-naïve patients receiving RTX experienced no glucocorticoid-related adverse events, whereas relapsed patients exhibiteda statistically significant reduction in steroid dosage and a decreasing trend in relapse frequency after RTX, although the latter did not reach statistical significance.

A positive trend was seen between both 0.2 Hz and 1 Hz thresholds and mediolateral RMSD, however, these associations did not reach statistical significance (0.2 Hz: β = 4.13 p = 0.083, CI −0.57–8.83; 1 Hz: β = 3.12, p = 0.053, CI: −0.045–6.3; Figures 4 , 5 , respectively).

Although some primary endpoints, like SRI4, did not reach statistical significance, belimumab showed a favorable trend in disease control and a lower incidence of serious adverse events.

In our analysis, there was a clear trend toward higher all-cause mortality and cardiovascular mortality in patients with lower ADAMTS13 activity in remission, though this did not reach statistical significance, likely because of the relatively small sample size (98 patients with remission ADAMTS13 activity measures) and small number of events.

There is a clear trend toward increased complication rates when thicker ADMs were chosen; however this did not reach statistical significance.

The pooled MD for protein oxidation rate showed a trend toward decreasing after LES intake but did not reach statistical significance (MD = −1.20, 95% CI: −4.66–2.27, P = 0.50) ( Figure 11 ).

Although a clear trend toward improved healing in Grade 2-infected wounds compared to Grade 4-infected wounds, the difference in histology scores between the Grade 4-infected wounds (histology score: 2.33 ± 0.58) and Grade 2-infected wounds (histology score: 4.25 ± 1.26) at day 14 did not reach statistical significance ( Figure 6M , p = 0.0857).

Although there was an apparent trend toward increased TTP in the Len+Dex arm, this did not reach statistical significance.

While lower DDS showed a trend toward increased frailty, it did not reach statistical significance in this specific model after adjusting for all covariates.

The expression of Prdm16 showed an increasing trend but did not reach statistical significance.

Older participants showed a trend of performing better than younger participants (YA: mean ± SD = 80.8 ± 7.9%, OA: 85.1% ± 6.5%), but this difference did not reach statistical significance ( z = –1.8, p = 0.07, Mann–Whitney U -test).

For linalool, β-caryophyllene, humulene, and methyl eugenol, the interaction between light spectrum and SNP treatment showed a marginal trend but did not reach statistical significance ( Table 4 , Supplementary Document S2).

Although ∆ argR + EV showed a slight trend towards reduced competitive fitness in the liver and spleen, this did not reach statistical significance and was not complemented by ∆ argR+ p argR .

Although a decreasing trend was also observed throughout the entire time course also for LCAT, particularly at the 4-hour mark, this trend did not reach statistical significance (data not shown).

Short-term fasting (≤3 days; k = 15) showed a trend toward reduced triglyceride levels (g = −0.335; 95% CI: −0.684 to 0.013), although this effect did not reach statistical significance.

Healthcare utilisation We observed a marginal trend in reduced healthcare utilisation; however, these did not reach statistical significance.

The association between high PIV and deeper myometrial invasion (≥ 50%) showed a trend but did not reach statistical significance ( P = 0.078).

When CAD-RADS 4a and 4b HRs were 4.87 (95% CI, 3.30-7.20) and 7.30 (95% CI, 5.44-9.80) were compared, an increasing trend was observed, although this did not reach statistical significance ( P = .10).

Among sirtuin family members, SIRT1, SIRT3, and SIRT4 exhibited >2-fold induction (log 2 FC ≈ 1.0–1.3), whereas SIRT5 showed a positive trend that did not reach statistical significance, likely due to low read counts and partial RNA degradation in irradiated samples.