“did not reach statistical significance”

While individual PAKs did not reach statistical significance in breast and lung cancers, a strong trend in PAK5, similar to prostate cancer was also observed in breast cancer patient survival (Figures 8 and 9 ).

Age at transplant showed a trend but did not reach statistical significance (HR, 1.12; 95% CI, 0.99-1.25; P = 0.06).

Responders based on Paris-I, Paris-II, and Rotterdam criteria showed a trend toward lower HCC risk than those of non-responders, although this difference did not reach statistical significance ( Table 4 and Fig.

The findings showed a slight trend toward faster improvement in skin symptoms, particularly rashes, among individuals receiving early RTX, although the effect did not reach statistical significance.

Protein levels of glutathione peroxidase 4 (GPX4), an enzyme that controls lipid peroxidation ( 25 ), showed a trend towards downregulation, but did not reach statistical significance ( Fig. 6 , F and I ).

The moderator test (QM = 7.78, p = 0.0999) indicated a near-significant trend, suggesting potential differences between intervention types, although the results did not reach statistical significance at the 5% level.

In contrast, neutrophil count (B = 0.714, P = 0.138) showed a positive trend but did not reach statistical significance, while monocyte count (B = 1.768, P = 0.362) was not significantly associated with preeclampsia.

Furthermore, the age at treatment onset showed a trend toward earlier initiation in the pandemic group (8.04 years) compared to the pre-pandemic group (8.65 years), although this difference did not reach statistical significance (p > 0.05).

Compared to saline-treated mice, the mRNA level of Ehhadh in lung tissue showed a decreasing trend but did not reach statistical significance ( P = 0.0594) in mice with neutrophilia-dominant allergic airway inflammation ( Fig. 2I ).

Furthermore, although the difference between the groups did not reach statistical significance, the IL-6 plasma levels showed a trend reduction over time after the FS was administered (pre–post treatment 8.0 ± 1.73 pg/mL vs. 4.8 ± 1.20 pg/mL) but not after the placebo was administered (pre–post 5.6 ± 0.94 pg/mL vs. 5.01 ± 1.07 pg/mL).

Additionally, an increase in the INR showed a trend toward an increased risk of a poor prognosis, although this did not reach statistical significance (aOR = 2.14; 95% CI 0.93–4.96, p = 0.074).

A Danish randomized controlled trial in which vitamin D3 (1200 IU daily) was administered to patients with CD showed a trend towards lower rates of clinical relapse compared to placebo, although it did not reach statistical significance [ 114 ].

Radiotherapy showed a trend towards reduced risk but did not reach statistical significance (OR = 0.49, 95% CI: 0.21–1.13, p = 0.094).

Age showed a trend toward significance but did not reach statistical significance.

Three analyses demonstrated a trend toward significance, though they did not reach statistical significance ( p = 0.056–0.066).

A new left bundle branch block (LBBB), the most common conduction disturbance after TAVI, showed a trend toward a lower PPM stimulation rate in our data but did not reach statistical significance.

Although there was a decreasing trend in overall appropriateness over the monitoring time ( Figure 6 ), this trend did not reach statistical significance. 4.

In the subsequent years, a segment with a decreasing trend was identified during 2007–2017 with an APC of -10.6 (95% CI, -13.6 - -7.6; p = < 0.001) and another segment with an increasing trend during 2017–2021 with an APC of 7.2 (95% CI, -6.2–22.5), although the latter did not reach statistical significance as indicated by the confidence interval.

Although the overall efficacy improvement did not reach statistical significance, the results suggest a positive trend in favor of OLD for wound management (Table 1 ).

The unloading group also showed a positive trend, although it did not reach statistical significance.

While Ro L treatment showed a trend toward reduced p-p38, p-ERK, and p-JNK expression, these changes did not reach statistical significance.

While the PFD and LROF groups exhibited an increasing trend, these changes did not reach statistical significance when compared to the MOD group.

Conversely, as delineated in Table 4 , within the male cohort, irrespective of whether TyG Q1 or TyG Q2 served as the reference, the DR risk associated with TyG Q3 and TyG Q4 did not reach statistical significance, nor was a significant trend of increasing risk observed.

A decreasing trend in immune cell number was observed in the sample treatment groups compared to the LPS group, although this trend did not reach statistical significance ( Fig. 4A - 4D ).

Interestingly, the expression of mcBOX, a repetitive element, showed a trend towards upregulation in the H3K9M group, although the change did not reach statistical significance.