“did not reach statistical significance”

While the lower dose (20 μg/mL) did not reach statistical significance, a decreasing trend in DNMT1 expression was observed compared to the H 2 O 2 and vehicle-treated group.

Although the association in the elevated glucose group (FPG≥5.6 mmol/L) did not reach statistical significance ( P = 0.072), possibly due to a relatively smaller sample size, the higher point estimate (OR=1.46) suggests a possible trend toward a stronger association.

Regarding the impact of capecitabine on OS, the complete cohort showed a trend toward improved survival in the post-BILCAP era, though it did not reach statistical significance ( p = 0.075).

The suppression of IFN-γ also showed a trend toward reversal, although it did not reach statistical significance.

After treatment, the positive drug group showed a trend toward increased colon length, although this did not reach statistical significance.

EV treatment showed a trend toward reduced iNOS expression; however, these changes did not reach statistical significance among different EV groups (Figure 6F ).

In contrast, PGC-1α expression exhibited an increasing trend; however, this change did not reach statistical significance.

Although digital interventions showed a trend toward improvement in executive function, this effect did not reach statistical significance [SMD = -0.41, 95% CI (-0.85, 0.02)].

RF ablation showed a trend toward smaller isolated LAPW area (6.1 ± 3.9 cm2), although this difference compared with P-PFA did not reach statistical significance (p = 0.087).

Umbilical artery pH demonstrated a negative trend with increasing sFlt-1/PlGF values; however, this association did not reach statistical significance after adjustment (estimated change −0.0076 per doubling; p = 0.070).

Furthermore, while a significant reduction in nasal choroidal thickness was observed exclusively in the left eye ( P < 0.01), there was also a notable trend toward lower nasal choroidal thickness in patients with carotid plaques, although this difference did not reach statistical significance (Fig. 2 ).

Among them, the implantation of pacemakers showed a decreasing trend in the CHD group, but did not reach statistical significance (OR = 0.39, 95% CI: 0.15–1.05, p = 0.06).

Among the other covariates included in the model, pathologic tumor stage ≥ pT3a showed a trend toward association with tertiary Gleason pattern 5 but did not reach statistical significance (aOR, 2.14; 95% CI, 0.98–4.86; p = 0.061).

Prior DAIR showed a trend toward lower failure rates but did not reach statistical significance (HR = 0.043, 95% CI: 0.002–1.039, p = 0.053).

Group 3 showed a trend towards a poorer prognosis in the female subgroup, but the difference did not reach statistical significance (P = 0.0568) (Table 5 ).

In the aforementioned study, although the difference in DAO levels between the study and control groups did not reach statistical significance, DAO levels in the critical group showed an increasing trend, suggesting possible intestinal mucosal cell damage in severe infection states.

Among immunocompetent patients, hypoglobulinemia remained a significant predictor of CM (OR = 0.812, 95% CI: 0.682~0.967, p = 0.019), while underlying diseases were by definition absent, and hypokalemia showed a trend toward association but did not reach statistical significance (OR = 0.153, 95% CI: 0.019~1.247, p = 0.079).

ECMS remained significantly prognostic in the HPV-negative subgroup, while in the HPV-positive subgroup it showed a trend consistent with the overall cohort but did not reach statistical significance.

Increasing age showed a trend toward higher risk of failure but did not reach statistical significance ( P = 0.052).

Notably, while this group exhibited a mild trend toward reduced inflammation, the effect did not reach statistical significance.

Although the difference did not reach statistical significance, a favorable trend toward improved wound closure was observed in the GPP@VP NIR group.

In the subgroup of participants with poor diet quality (HEI-2015 < 60), the association between observed ASVs and RA showed a trend toward significance, but did not reach statistical significance ( P = 0.094).

Differences in career growth according to years of experience approached but did not reach statistical significance, F (4, 365) = 2.39, p = 0.051, suggesting a possible trend toward variation across experience levels.

Variables including numeric radiosurgery dose (HR = 1.35; 95% CI 0.99-1.87; p = 0.061) and loss of coordination at clinical presentation (HR = 2.74; 95% CI 0.94-8.02; p = 0.065) showed a trend towards association but did not reach statistical significance.

Similarly, smear grading showed an increasing trend with higher relative centrifugal force, although this did not reach statistical significance ( p = 0.212).