“did not reach statistical significance”

Case series and case- control cohort studies of patients with postictal psychosis showed a trend toward high rates of seizure clustering before postictal psychosis, though this did not reach statistical significance in these underpowered studies ( 6 , 10 ).

Although in some models there was a clear trend in the decrease of IFNAR1 expression in M-MDSC as compared to Mon, it did not reach statistical significance (Fig. 1c ).

Although MDTM showed a trend toward an improved survival rate among patients with stage IV HNC, it did not reach statistical significance [combined HR = 0.81, 95% CI (0.59–1.10), Z = 1.35, P = 0.18, Figure 3 ].

NP-led MET calls showed a trend toward decreased mortality within 24 h of index MET call, but this did not reach statistical significance (3.4% vs. 7.2%, 0.47 (0.21–1.05); p = 0.06).

While we found there was a clear trend in PDGFR‐β immunoreactivity in the order: old controls >PSND > PSD (Figure 5 A), the mean values for PDGFR‐β assessed by ELISA did not reach statistical significance ( P > 0.05).

In a follow-up study by Dreyer et al., the same techniques found a favorable trend in ICP, CPP, and patient outcomes in the OMT cohort; however, they did not reach statistical significance [ 20 ].

The mRNA expression of CXCL10 also showed a decreasing trend in the HJ-treated group, although it did not reach statistical significance ( Fig. 5D , P=0.086).

A weak trend in the same direction was observed between the time spent looking at the target and localisation error although this did not reach statistical significance ( p = 0.128).

In the analysis for TIM3, CAR-αPD-1 and CD19 CAR-Trap showed a trend toward the inhibition of TIM3 upregulation, but it did not reach statistical significance ( Figure 5 D).

While the decrease in systolic BP did not reach statistical significance ( Figure 2A ), a highly significant decrease in diastolic BP was evident in REL-1017 vs. placebo subjects ( Figure 2B ), both at 2 and 24 h after drug administration.

These differences were consistent with a numerical trend towards shorter disease duration and lower serum myoglobin in the CG, which did not reach statistical significance (Table 1 ).

Genes that are upregulated in exhausted T cells showed a trend toward negative enrichment in our data set but did not reach statistical significance.

We found that (1) Chinese-English bilinguals showed a significant priming effect for congruent binomials but no facilitation for English-only binomials, (2) English–Chinese bilinguals showed a trend toward priming for congruent binomials, which did not reach statistical significance, and no priming for English-only binomials, (3) English monolinguals showed comparable priming for congruent and English-only binomials.

Consistent with variable levels of fluid recovery during bronchoalveolar lavage (BAL), the levels of virus in BAL were more variable, and showed a trend towards a more rapid decline of sgRNA levels in CoV-2-mAb-treated animals, that did not reach statistical significance ( Fig 5C ).

Lower CSF α-syn and t-tau levels showed a trend of association with higher MDS-UPDRS III total scores at baseline, however, generalized linear models did not reach statistical significance (CSF α-syn, β = − 7.15, SE 3.85, p = 0.065; CSF t-tau, β = − 0.62, SE 0.34, p = 0.069). 311 PD patients showed MoCA total scores greater than 25 at baseline and were classified as PDNC.

Although there was a numerical trend toward a greater number of HAT in Group B, it did not reach statistical significance.

Cx32 KO EAE mice (10.8 ± 0.45 dpi, n = 5, p > 0.05) showed a trend towards an earlier EAE onset than WT EAE mice; however, it did not reach statistical significance ( Figure 1 E). 2.2.

Overall, reactivity towards the two different V1V2 subunit proteins was comparable, with a slight trend towards higher reactivity of sera from animals immunized with highly stabilized clade C trimer ConCv5 KIKO trimer (group 5) but also BG505 SOSIP.664 (group 6), which, however, did not reach statistical significance.

In the analyses including the extreme values ( Table S2 in Additional file), the significant increase in CSF NfL in the low burden group in definition 1 was lost ( P = 0.051). In definition 2, CSF neurogranin and NfL also showed a trend to increased values in the low burden group, but did not reach statistical significance ( P = 0.081 and P = 0.080 for CSF neurogranin and NfL, respectively) (Table 3 , Fig. 1 ).

The analysis showed a trend toward higher levels of C1q in the putamen of individuals with MSA, where three MSA patients exhibited high C1q levels compared to neurological healthy individuals, but it did not reach statistical significance ( P = 0.15).

Q725A showed a trend towards being more functional than the wild-type but this did not reach statistical significance and no effect was recorded for Q990A.

Overall, unadjusted odds ratios showed a positive trend of association between breast cancer risk and PER3 VNTR long repeat allele, although it did not reach statistical significance under any tested model.

A study conducted by a single center in Hong Kong, China, on the trends in ROP in preterm infants <32 weeks from 2006 to 2015 found a decreasing trend in the incidence of type 1 ROP (severe ROP requiring treatment) for the subgroup with gestational age <28 weeks, although it did not reach statistical significance ( 21 ).

Gene expression of CACNA1C (encoding the alpha-subunit of the LTCC, Figure 2 A) showed a trend, though it did not reach statistical significance, towards a reduction in miR-199a+miR-22 HL-1 cells compared to miR-NC.

Medium to large solid fields showed a trend towards unfavorable outcome, however this did not reach statistical significance ( P = 0.09).