The latter was highly significant ( p = 0.0012).
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However, this difference turned out to be entirely due to the AD patients without depression, who had a highly significant lower PVN-PACAP level compared to the controls ( p = 0.0012).
A subgroup analysis, stratified by the control group’s intervention, showed a highly significant difference between subgroups (p=0.0012).
While comparing the IS and IT TIL values with their corresponding breast cancer Immunohistochemical subtype, it was found that TNBC (p=0.0008) showed a highly significant association with the IS and IT TIL score followed by HER2BC (p=0.0012) exhibiting the same, whereas HRBC (p=0.3582) did not show a significant relation with the TIL score.
Based upon the frequency of these alleles in the SDP (11/18 alleles for the upstream marker and 0/18 alleles for the downstream marker; Table S3 ), this difference is highly significant ( p = 0.0012 for the upstream markers, p <0.0001 for the downstream marker, Fisher’s exact test).
We found that the reduced number of Utf1 (−/−) -tomato embryos was statistically highly significant (p = 0.0012) (Table 1 ).
Highly significant IMP resistance levels were observed for Stenotrophomonas (42.8%) (χ 2 = 18.026, p = 0.0012).
However, after 24 h, there is an increase in the expression of phospho-p38 MAPK, which is highly significant at 48 h compared with its control group ( p = 0.0012; Figure 4D ).
Tumours showing high levels of expression showed a highly significant excess of allelic imbalance (67 loci imbalanced vs 54 balanced) over those with low-level (42 imbalanced vs 81 balanced) expression ( P =0.0012).
This analysis revealed a highly significant association between the turquoise module and pathological T stage (cor=−0.21; P=0.0012; Fig. 3B ); however, radiotherapy was not significantly associated with the turquoise module in this analysis (cor=0.035; P=0.69).
A highly significant positive correlation ( r = 0.75, p = 0.0012) between marker density and the intrachromosomal LD blocks was observed ( Figure 3 ).
TBS Carcass mass and ADD had highly significant effects on TBS (repeated measures ANOVA, carcass mass effect: F 3,6 = 21.9, P = 0.0012; ADD effect: F 6,36 = 313.4, P < 0.0001, Fig. 13 ), effect of carcass clothing was insignificant ( F 1,6 = 0.09, P = 0.77) and the interaction of ADD and carcass mass effects was highly significant ( F 18,36 = 11.5, P < 0.0001, Fig. 13 ).
Interobserver variation was highly significant for wax impression method ( P = 0.0012), significant for the radiopaque wax impression method ( P = 0.0418) and was not found to be significant for the computer-assisted method ( P = 0.5577).
There was also a highly significant differences in parasitaemia between both clinical categories ( p =0.0012, Kruskal-Wallis test).
Highly significant correlation was observed between Ψ w and the photosynthetic pigments (chlorophyll, r = 0.8532, p < 0.0012; carotenoids, r = 0.8821, p < 0.0007).
Analysis of variance (ANOVA) demonstrated that the model was highly significant (F = 17.74, p = 0.0012), with a determination coefficient R 2 of 0.88 and adjusted R 2 of 0.83, confirming the reliability of the regression.
Incubation of whole blood samples from healthy volunteers with LPS revealed a marked 4.3-fold increase in CD45 expression on endotoxin-stimulated granulocytes from 26,898 ± 2985 to 114,144 ± 5293 ( p < 0.0001), and a gradual, but highly significant, increase on lymphocytes from 119,202 ± 8970 to 158,107 ± 6564 ( p = 0.0012) and monocytes from 209,266 ± 15,953 to 284,693 ± 11,880 ( p = 0.0005).
Given that only 13.3% (3004/22500) of the probes analyzed were overexpressed in those experiments, this enrichment is highly significant (p = 0.0012; Chi square test with Yates correction, 1 degree of freedom).
Among the transcripts differentially expressed in wild type POU3F4-transfected cells compared to control, a highly significant upregulation (log2-fold change = 3.488, false discovery rate-adjusted p -value = 0.001281) was detected for the amino acid transporter solute carrier family 6 (proline imino transporter), member 20 ( SLC6A20 , SIT1, XTRP3).
P mass was highly significant in the model ( P = 0.00129), indicating different J max – V cmax relationships with leaf P mass .
Statistical evaluation using an exact test for equality of Poisson rates under equal exposure confirmed that this enhancement is highly significant ( p = 0.0013).
The antibacterial analysis in our study has yielded highly significant results in p -values against the Gram-negative bacterial strains E. coli ATCC ® 25922 ( p = 0.0013) and S. dysenteriae ( p = 0.0059), indicating the ability to cross the outer membranes, unlike CFS, to release ions.
The difference between cells co-injected with collagen and SISgel was highly significant (p = 0.0013), but the difference between cells co-injected with collagen and Matrigel was not (p>0.05).
However, while low and intermediate vaccine dose are associated to highly significant contraction at 6 months (Student t test for paired data w4/w24 L p = 0.0013, I p = 0.0008), it is not the case for high dose ( p = 0.0647), suggesting better persistence of neutralization activity with higher vaccine dose.
The difference between both groups (2.49, SE 0.76) was highly significant [confidence interval (CI) 0.99–3.98, p = 0.0013].