Analysis of correlation between the number of cases in DECs with those reported from non-DECs shows a highly significant correlation ( P = 0.0011) when the comparative datasets are offset by 4 years (i.e.
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The resulting difference between treatment groups for the mean change in visual acuity of individual eyes from baseline of RHODOS to the RHODOS–OFU study visit was highly significant, logMAR −0.228 (11 letters; P = 0.0011; Table 2 ), in favour of the idebenone group for patients carrying one of the three primary mitochondrial DNA mutations and logMAR −0.283 (14 letters, P = 0.0002) for patients carrying either the m.11778G>A or m.3460G>A mutation.
Histamine concentrations after 10 minutes showed a statistically highly significant correlation with DAO antigen concentrations in the 16 pregnancy samples ( P = 0.0011; correlation coefficient = 0.74).
ARRDC2 , located in the cytoplasmic vesicle and plasma membrane and predicted to be involved in protein transport 28 , showed a highly significant positive linear correlation to lesion growth rate ( R = 0.99, p = 0.0011) (Fig. 3 ).
The ISS ( p < 0.0001) and age ( p = 0.0224) however were significant risk factors, while BMI was highly significant and even revealed the strongest effect among the predictors ( p = 0.0011) (Table 2 ).
Highly significant positive correlations were found between DOC concentrations and the numbers of CTC + cells (r = 0.82, p = 0.0011) and EST + cells (r = 0.83, p = 0.0009).
The differences between CC+ and CC− were not significant on any testing day for the control group ( p = 0.60 and p = 0.13, for days 1 and 3, respectively); however, for the YKS group, the difference was highly significant ( p = 0.0011 and p = 0.023, for days 1 and 3, respectively).
The difference between monotherapy and polypharmacy was highly significant ( p = 0.0011 [t = 3.276; df = 748]).
Subregional analyses revealed that this increase was highly significant in the caudal DG (71%; p = 0.0011), but non-significant in the rostral DG (p = 0.29) ( Fig. 2A ).
At 14a1, the Col allele was over-transmitted by 68% and this difference was highly significant ( p-value = 0.00111), while it was only barely significant ( p-value = 0.0734) for the 14a2 hotspot, probably due to the lower CO number.
In the case of Paso 144, the surface shows a curvature in T direction, as it is expected, since T 2 term was highly significant ( P < 0.00112).
However, the non-parametric Kruskal–Wallis test, applied for the comparison of all three groups, identified a highly significant overall difference (χ 2 = 13.56, df = 2, p = 0.001136).
The highly significant p -value ( p < 0.001157) confirms that patterns are present that depend on specific TFs; indeed, the association between frequency and AUC is definitely not driven by chance and has correlation value of 0.35, suggesting that while frequency has a significant influence, it is not the only factor playing a role in recognition.
Of the detected DE proteins, 38 had expression changes that were highly significant (below the Benjamini-Hochberg procedure p < 0.00116) ( Supplementary Table S1 ).
This highly significant change in the distribution of binding loci ( P = 0.00116, Fisher’s exact test) could indicate a condition-dependent functional mode for NtcA in Synechocystis .
The Kruskal–Wallis analysis showed highly significant differences in mean TPC values between control and samples treated with HA-MNP at different concentrations, both in stems ( p = 0.001175) and roots ( p = 0.001172).
Analysis of variance (ANOVA) demonstrated that the model was highly significant (F = 17.74, p = 0.0012), with a determination coefficient R 2 of 0.88 and adjusted R 2 of 0.83, confirming the reliability of the regression.
Such a correlation was found to be highly significant in children from higher grades ( r = 0.82, p = 0.0012, Fig. 4 ), surviving Bonferroni correction for multiple comparisons between the two conditions and across the three groups ( p corr = 0.007).
However, after 24 h, there is an increase in the expression of phospho-p38 MAPK, which is highly significant at 48 h compared with its control group ( p = 0.0012; Figure 4D ).
After 8 and 16 weeks of fortnightly therapy, levels had risen to 105% and 89% for oestradiol and 110% and 86% for oestrone respectively. Cortisol levels fell, from a pretreatment level of 490nmoll1' to a mean of 334nmoll1' after 2 weeks, then rising to 370 nmol l-' after 8 weeks (Figure 3), the fall between weeks 0 and 2 being highly significant (P = 0.0012).
Although not clearly dose-dependent, the effect of oil exposure was highly significant (ANOVA P = 0.0012) with salmon from all oil treatments having shorter outflow tracts relative to controls (all P values < 0.005) except for the lowest ΣPAH exposure (9.8 μg/L).
This analysis revealed a highly significant association between the turquoise module and pathological T stage (cor=−0.21; P=0.0012; Fig. 3B ); however, radiotherapy was not significantly associated with the turquoise module in this analysis (cor=0.035; P=0.69).
Interobserver variation was highly significant for wax impression method ( P = 0.0012), significant for the radiopaque wax impression method ( P = 0.0418) and was not found to be significant for the computer-assisted method ( P = 0.5577).
We found that the reduced number of Utf1 (−/−) -tomato embryos was statistically highly significant (p = 0.0012) (Table 1 ).
Despite this, the eliminations in this study ( Figure 4 a,b) were highly significant ( p = 0.0012): in a system with three plants the removal on average was 79 and 80%; in systems with six plants 80 and 82%; in systems with nine plants 61 and 64%, and in controls without vegetation 84 and 90% in PET and PRS substrate respectively.