“highly significant”

The role of recombination in mixing the genetic pool of HCMV at the whole genome level is confirmed by a highly significant rejection of the pairwise homoplasy index (PHI) test ( Bruen et al. 2006 ; P < 10 − 8 ).

We found that G→T transversions were over-represented in both the maize and sugarcane evolution experiments, and that this over-representation was highly significant when either the MSV-Tas sequence dataset was analysed alone (chi square p < 10 -8 ) or when all the mutation data from both experiments were considered collectively (chi square p = 5.4 × 10 -7 ; Table 1 ).

Gene Ontology analysis of this cluster reveals a highly significant ( P ≤10 −8 ) number of genes that are associated with cell defense response ( Figure 5D ).

Moreover, the correlation between ensemble mean forecasts of SST EEIO and their error is highly significant (r = 0.77, p < 10 − 8 ), i.e. small real multi-annual variations in the state of the IOD are vastly exaggerated by the hindcasts and indicate state-dependence of SEAS5 forecast errors in the EEIO.

The univariate ANCOVA model applied (equation 2 ) revealed very highly significant differences between (1) the culinary oils investigated ( p < 10 −8 , with the exception of cis -2-alkenals for which p = 4.85 × 10 −3 ), and (2) sampling time-points ( p < 10 −8 ) for all aldehydes monitored.

These genes were chosen on the basis of showing highly significant self-linkage ( p < 10 −8 ) and at least a 1.2-fold difference in expression between segregants bearing the BY and RM alleles, such that no false positives and only one chance trans linkage due to a nearby gene were expected (see Materials and Methods ).

The analysis demonstrated a highly significant result (test statistic = 0.0, p < 0.00000001), indicating that median stent migration was greater than zero and that measurable displacement occurred between the three-month and one-year intervals.

Paired statistical tests across all datasets indicate that these improvements are highly significant ( p < 1 × 10 −8 ).

There were highly significant correlations between the FDDB and PRODI ® tools for daily energy and macronutrient intakes (correlations ranging from 0.849 to 0.929; p ≤ 10 −8 ) ( Table 2 ).

Notably, the gene candidates THBS1 and IL18RAP exhibited highly significant upregulation (LogFC > 1.9, p < 10−8) in the independent GSE28750 cohort, confirming that our network-based prioritization captures clinically relevant expression changes.

The effect size of the differences observed is very large, and the P -values highly significant ( P < 10 −8 ).

We recovered the PCDH15 locus as a highly significant sweep region consisting of more than 300 variants spanning 369.5 kb ( p -value < 10 –8 ), indicating a strong signature of selective sweep.

There was no significant difference in the family effect between years (interaction family × year not significant; LRT: χ 2 = 1.2; df = 2; p = .552), but the family effect was highly significant ( χ 2 = 32.6; df = 1; p = 1 × 10 ‐ 8 , Table S2 ) and the heritability of the sensitivity to vernalization was 0.19 (±0.04) (Table 2 ).

Cellular RNAs that increased in concentration slowly and steadily throughout most of the observed infectious cycle, which are grouped in cluster 5, exhibited a highly significant enrichment in RNAs specifying proteins that participate in the establishment and maintenance of chromatin structure ( P = 10 -8 ).

Since the distributions of time budget left is not Gaussian, we performed a Wilcoxon signed rank test comparing the both distributions, which was also highly significant ( z = 5.44, p < 10 −8 ).

These genes were either associated with resistance to both lead and cadmium in both sexes or had highly significant ( P < 10 −8 ) effects in any one condition.

Welch’s t -tests yielded directionally consistent and highly significant differences (e.g., Depression p ≈ 1.0 × 10 −8 ).

We chose SNPs for the model that were highly significant and not in strong LD with each other (i.e., P < 10 -8 for r 2 between SNPs).

This test also shows that the difference between AI and human text is highly significant (− log 10 (p)≈8, p ≈ 3.69 × 10−9), and it is due to AI text often having less variety in its vocabulary.

Indeed, we found a highly significant association between high histone signals in FFPE-CUTAC samples and rapid patient recurrence ( p <10 −8 , Fig. 4B left, fig.

In this analysis, 263 p53 target genes were co-bound by JMJD3, which gives a highly significant overlap between JMJD3 and p53 target genes (p<10 −8 ).

Biological underpinning of the shared genetic components—translational evidence from mice For each of the Master PCs, the top-500 correlations across all records of the Amygdala Cohort Database, ranked by the Genetic Correlation (Spearman's rho), were strong (absolute value ranging from 0.7 to 0.9), and highly significant ( p < 10 −8 , Supplementary Tables 5, 6 ).

cellulosilyticus exhibited a highly significant increase in abundance (p < 1 × 10 −8 ) in Apoe −/− mice, and R. intestinalis had a slightly higher (p = 0.025) relative abundance in mice gavaged with the combination of bacterial species compared to Apoe −/− control mice.

Because of this bias, PBIF modeling found a larger decrease in V T in cannabis smokers (−27% in the prefrontal cortex compared with −19% using full input), and the group×region interaction was statistically highly significant (F = 17.1, p = 0.00000001) ( Fig. 2B ).

XPO4 and IP6K1 have highly significant differences in effect ( p = 1 × 10 −8 , 3.2 × 10 −5 ), both reflecting large effects in Thomsen et al. and smaller or zero effects in other studies.