“highly significant”

In this independent data, we observed a highly significant predictive performance ( r = 0.34 CI 90% : [0.14 0.53], p = 0.009, Fig. 1c – External model performance).

This difference was highly significant in univariate analysis (OR 0.29, 95% CI 0.07–0.73, p = 0.009).

After 48 months, a highly significant difference in fT4 level could be noted (active: 7.53 pg/mL vs. placebo: 8.88 pg/mL; p = 0.009).

Spearman's correlation coefficients confirmed a highly significant and positive correlation between PM% and PMI score ( r = 0.71, p = 0.009) only for undiluted semen.

The “time” and “school type” interaction was also highly significant ( p -value = 0.009) which showed that the mean scores of public school students were initially lower than those of private schools in both the baseline (5.0 v/s 5.2) and posttest I (5.7 v/s 6.1).

Although this association only achieved borderline significance, there was a highly significant genotype by diabetes interaction (p = 0.009).

The correlation between the difference in measured and predicted skeletal muscle mass and the actual measured skeletal muscle mass was highly significant ( r 2 = 0.90, P = 0.009).

Crucially, a significant interaction effect was found in the comparison of data from the hand movement and control conditions ( F (1,25) = 9.24, p < 0.006) and even after removal of shift and transposition errors from the analysis, this critical interaction effect remained highly significant ( F (1,25) = 8.01, p < 0.009).

There was no significant negative correlation between the change in the global methylation degree of CpG1 and gene expression ( r = −0.462, p = 0.357), of which the change in the degree of methylation of 17 CpG sites was negatively correlated with gene expression, and the mC-20 site showed a highly significant negative correlation with gene expression ( r = −0.920, p = 0.009).

HCM patients showed highly significant LV wall thickening (LVT) compared to the healthy subjects (LVT HCM = 14.94 ± 2.98 mm; LVT Healthy = 11.77 ± 1.27 mm; P = 0.009) ( Figure 1B ).

Effects of Curcumin on aCSK A highly significant decrease in SMA expression was seen when comparing curcumin 20 μM and 50 μM + TGF-β1 to control + TGF-β1 ( p = 0.009 and p = 0.002, Table 1 , Figure 3 ).

We demonstrate a dose-dependent effect on hRECs by increasing exposure to 1, 5, and 10 mM caffeine citrate, resulting on average in highly significant CBF excitation of 14.2% ( n = 7; p = 0.009), 18.6% ( n = 6; p = 0.023), and 28.8%( n = 6; p = 0.014) over CBF b respectively (Fig. 1 d).

In the sibling-paired analysis, the decrease in total motor score was highly significant, p = 0.009, driven by a decrease in fine motor score, p = 0.008.

In the study, the association of periodontal status to DMFT was highly significant ( r = 0.161, P = 0.009), suggesting that young adult students with poor periodontal status have more prevalence of decayed teeth.

A highly significant relationship and a moderate association with anemia (-2.76, CI 95% -9.26 to -0.22; p -value = 0.009) and strong association with very highly significant relationship was noted with COVID-19 (-5.68, CI 95% -6.34 to -0.48; p -value = 0.000) and sun exposure (5.71, CI 95% 0.80 to 0.49; p -value = 0.000).

Comparison of the entire group (n=8) showed highly significant down-regulation when quantitated by relative densitometry units (p<0.009).

Resistance was more common among urinary than among fecal strains within each phylogenetic group, the difference being highly significant for groups B2 and D strains ( p = 0.009 and p = 0.003, respectively) and of borderline sig-nificance for groups B1 and A strains ( p = 0.05 for both).

After adjusting for other variables in a multivariable model, the protective effect of the intervention remained highly significant and even stronger (AOR 0.07, 95% CI 0.01–0.53, p = 0.009).

This difference was most evident in the earlier stage group (stage 1 to 2) with median overall survival of 30.0 months (95% CI: 26.4 to 35.1 months) in the warfarin group compared to 23.7 months (95% CI: 19.6 to 31.8 months) in the DOAC group, yielding a highly significant HR of 1.24 (95% CI: 1.06 to 1.45, p = 0.009).

No significant difference could be found on comparing the distraction conditions without belt ( p = 0.240), but a highly significant difference could be observed when comparing the distraction conditions with the belt in compass mode ( p = 0.009).

Despite the non-significant difference in COVID-19 infection rates across the 4 months ( p value = 0.076), a highly significant linear by linear association/trend was encountered ( p value = 0.009) (Fig. 4 ).

Patients infected only with OROV showed a higher non-significant frequency of males (52.4%), but in the case of OROV + DENV co-infection the frequency of males (66.7) was highly significant (p < 0.009).

Furthermore, correlation analysis revealed a highly significant positive correlation between CD56dim natural killer cells and ACAA2 (cor = 0.291, p = 0.009), whereas a highly significant negative correlation was observed between central memory CD4 + T cells and DAP3 (cor = −0.381, p = 0.0004; Figure 5C ; Supplementary Table S3 ). 3.6 DAP3 , BIK , and ACAA2 were regulated by multiple factors Using the NetworkAnalyst database, 24, 15, and 27 TFs were predicted to regulate the expression of DAP3, BIK, and ACAA2.

Association of Clinicopathologic Characteristics with Diagnosis of POD Univariate correlation analysis revealed a highly significant correlation between the occurrence of POD and elevated ACCI in our retrospective cohort ( p = 0.009).

The difference in survival rate between biofilm associated cells and corresponding planktonic cells was apparent after 2h of incubation with the phage, and after 5h of incubation the difference between the survival of biofilm associated cells as compared to planktonic cells was highly significant both for phage JSF4 (p = 0.0090) and for JSF3 (p = 0.0066).