This showed a highly significant positive relationship ( r = 0.83, p = 0.00019) between the two variables.
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The interaction between MLEC and TMEM59 was highly significant ( p = 0.00019, β = 2.469), with higher expression of both genes correlating with increased predicted probabilities ( Figure 10I ).
Linear regression analysis showed that the slope of the line was not significantly different from zero for normal Aβ degradation when the threshold is four but it was highly significant ( p = 0.00019) for the AD degradation rate (Figure 4 A, B).
Cluster 35 shows a highly significant enrichment for genes associated with gene ontology (GO) terms involving neurogenesis (Additional file 8 : Table S2, P = 1.91 × 10 −4 ) consistent with the peak and decline of neurogenesis from E12.5 to 16.5.
The results were conclusive: only IL-18R1 maintained a highly significant direct causal effect on AD (β = 0.023, P = 1.92 × 10 −4 ), whereas the direct effects of both PA-GPC ( P = .074) and IL-18 ( P = .084) became non-significant.
A t-test was also performed to validate significant enrichment of repetitive elements in the intergenic regions which gave a highly significant p-value for the enrichment of repetitive elements in the intergenic regions (p-value = 0.0001957 in S . tuberosum and p-value = 6.018e-11 in S . lycopersicum ).
These correlations were highly significant ( p < 1.96 × 10 − 4 ).
All correlations are highly significant (p<0.0002), indicating the null hypothesis that the correlation is equal to zero can be rejected.
acidophilus , for the duration of their hospital stay and saw a highly significant decrease in both NEC and NEC-related death ( p <0.0002 and p <0.005, respectively) ( Table 1 ).
However, the highly significant difference between the relative occurrence of bacterial families in ME and E lakes (ANOSIM r = 0.99, p = 0.0002) leads to the conclusion that the meso-eutrophic lakes were inhabited by different groups of bacteria than the eutrophic ones.
21 Comparing our 100 smoking genes identified in C‐SM versus C‐NSM with the top 25 smoking‐related genes identified in this previous meta‐analysis ( n = 25), we found three genes (GPR15, LRRN3, and CLDND1) overlapped, which is highly significant based on a hypergeometric probability test ( P < 0.0002).
Although only 16 among the 702 participants had experienced a stroke, a highly significant association to the Lewis(a−b−) blood group was observed for this group (P = 0.0002, OR: 22.28; CI 95: 4.72–131.63 - Table 2 ).
Moreover, rectal mDCs after the 1st Ad-SIV immunization exhibited highly significant positive correlations with rectal IFN-γ + CD8 + memory T cells specific for SIV Gag ( r = 0.7356, p = 0.0002), SIV M766 Env ( r = 0.5979, p = 0.0054), and SIV CG7V Env ( r = 0.7615, p < 0.0001).
[ 5 ] reported median lesion size as highly significant (3 cm versus 2 cm; P = .0002) in a study of 40 patients with metastatic cSCC when compared to 153 cSCC patients without metastases.
Analysis of 27 benign and 23 pathogenic variants co-occurring at 22 residues again showed that the difference between the two groups was highly significant ( P = 0.0002) and that, as a group, pathogenic missense changes were more strongly destabilizing than benign ones at the same position (average ΔΔG value by group = 6.81 and 2.18 kcal/mol, respectively) [ Fig. 3(c )].
Between 250–280 ms the DE was highly significant in both tasks (Numerical: p = 0.0002.
We observed a highly significant and highly variable F IS ( F IS = 0.285, p -value > 0.0002, 95% CI = [-0.021, 0.261]) ( Fig 3 ).
At the lower dose of sucrose and higher dose of OLE, a highly significant decrease ( p < 0.0002) in peak glucose was observed in all individuals (Fig. 8 ).
A linear model confirmed the expectations of a highly significant and increasing relationship ( t -value = 4.04, p = 0.0002, R-square 0.241).
3C–F ; the decrease was highly significant in the lung ( P = 0.0002) and almost achieved significance (p = 0.069) in the heart).
With age included as a covariate and using the Tukey-Kramer adjustment for multiplicity, the comparison between CH-NATs and AD was highly significant (p = 0.0002) whereas the comparisons between CH-PATs and CH-NATs and between CH-PATs and AD were not significant (p = 0.09 and 0.12, respectively).
9 , bottom row); these differences were significant for all groups including the LVS Δ capB vector in experiment 1 (ranging between P < 0.05 to P < 0.01) and for all but the parental vector and one vaccine in experiment 2 (ranging from P < 0.05 to P < 0.0001); combining all LVS Δ capB and r LVS Δ capB /Bp vaccines, the increase in antibody to HI Bp82 was highly significant ( P = 0.0002 and P < 0.0001 by two-tailed t test in experiments 1 and 2, respectively).
Therefore, it was found that the association between frequency of smokeless tobacco usage and the presence of oral mucosal lesions was highly significant (p= 0.0002*).
Highly significant association was seen between breast cancer and carrying either of the mutations (OR 1.86, 95% CI 1.32–2.49, P = 0.0002).
This translated into a highly significant increased rate of survival within mAb treated mice compared to control mice (31283 p = 0.0002; 31259 p = 0.0004; 29044 p = 0.0003), as displayed in Fig 7C .