Barely Significant
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“marginally non-significant”

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marginally non-significantP = .0581.2× alpha
The average causal mediation effect was small and marginally non-significant ( P = .058), with the proportion mediated approaching zero, indicating no substantial indirect effect through hypertension (Supplementary Table 3 and Figure 3 ).This analysis was exploratory and not intended for causal inference.
marginally non-significantp = 0.0581.2× alpha
trichiura (prevalence from 19.4% to 11.7%, OR 0.44, 95% CI 0.26–0.73, p = 0.0040) and a marginally non-significant reduction in odds of infection of Strongyloides spp (prevalence from 4.3% to 1.6%, OR 0.33, 95% CI 0.12–0.89, p = 0.058) in the IVM-1 arm ( Supplementary Table S3 ).
marginally non-significantp = 0.0581.2× alpha
No significant relationships were detected between any diversity index and AOO under either dataset, with the exception of a marginally non-significant association between Pielou and AOO when single-sample species were excluded (R2 = 0.476, p = 0.058).
marginally non-significantP = 0.0581.2× alpha
All linear regressions of the effects of P max on the number of selection candidate loci and significant trait-locus associations showed negative, albeit marginally non-significant relationships ( Dfdist global comparisons r 2 = 0.315, P = 0.058; BayeScan global comparisons r 2 =0.155, P = 0.148; MatSAM r 2 = 0.239, P = 0.09; all P values one-tailed: Figure 4 ).
marginally non-significantp = 0.05871.2× alpha
Hypotension was significantly increased (RR 2.67; 95% CI 1.45–4.92; p = 0.0112; I2 = 0%), with leave-one-out sensitivity analyses yielding stable estimates ranging from RR 2.33 to 2.86, though omitting Laffin 2025 rendered the result marginally non-significant (RR 2.66; 95% CI 0.93–7.56; p = 0.0587).
marginally non-significantp =.0591.2× alpha
We found a small, marginally non-significant positive period × time interaction ( β = 0.002, 95% CI [−0.000, 0.004], t (49) = 1.946, p =.059), a non-significant effect of time ( β = −0.001, 95% CI [−0.003, 0.000], t (49) = −1.605, p =.117), and a significant negative effect of period ( β = −0.073, 95% CI [−0.135, −0.012], t (49) = −2.402, p =.021) (Supplementary Table S6, Figure S4).
marginally non-significantp = 0.0591.2× alpha
Urban residence showed a marginally non-significant association ( p = 0.059) with smaller networks, suggesting potential differences in social network structure between urban and rural populations, though findings are inconsistent with some studies reporting enhanced urban social networks [ 33 ].