“marginally significant”

The binary-smoking external validation analyses also identified cg24823993 as a marginally significant methylation site. cg22515201 in a CpG island within 200 bp of the TSS in PLA2G6 is the most significant CpG locus in the gene associated with cigarette smoking.

As there are two independent sites and two strictly independent marker sets, we considered P ⩽0.05/4=0.0125 to be statistically significant and P ⩽0.1/4=0.025 (but>0.0125) to be suggestive or marginally significant for the SNP tests and for interactions between SNPs and radiation dose.

Alertness On a descriptive level, in the Alertness subtest of the TAP, the mean reaction time, SD and phasic alertness demonstrated increased mean test scores for the post-training condition; however, only the reaction time change was marginally significant, and this finding was only significant with a small effect size.

In addition, two SNPs (rs10474352 T allele, OR=0.897, 95%CI: 0.800 to 1.006, P =0.062 and rs10816625 G allele, OR=1.113, 95%CI: 0.991 to 1.250, P =0.071) have a marginally significant association with breast cancer risk.

Figure 2 shows that healthy subjects who received naloxone had a marginally significant increase in their ratings of pleasantness ( Fig. 2a ), but no effect on ratings of intensity ( Fig. 2b ).

Although some of the results for the secondary outcomes were marginally significant, this trial was not powered for the secondary outcomes; also, we compared the combined treatment against each group using one active treatment alone.

However, there was a marginally significant main effect of severity, in that participants in the negative condition gave higher ratings (M negative = 2.49, SD = 1.71) than participants in the neutral condition, (M neutral = 2.04, SD = 1.72), F (1,196) = 3.47, p = .06.

For cancers such as biliary tract (gallbladder cancer), although fascin is not an independent prognostic indicator, it is marginally significant in correlating with poor prognosis ( Machesky and Li, 2010 ).

The findings show a positive relationship between women's current age and obstetric fistula, and almost all coefficients appear to be marginally significant.

In contrast, our evaluation of changes in 82 biosets from chemically-treated primary hepatocyte cultures, including chemicals that feminize the liver in vivo , showed that STAT5b function is rarely altered in vitro , and when altered, the changes are marginally significant compared to those seen in in vivo comparisons.

Interestingly, even if marginally significant, a lower percentage of MES cells was observed among patients with liver localizations and CNS involvement.

The results showed a marginally significant effect of IMC performance, M PASSED_IMC = 1.58 vs.

Although statistical significance was observed in this study, we acknowledge that the clinical significance in this study might be moderate because of the marginally significant and low HR.

Multivariate analyses on child stunting In adjusted analyses, the positive effect of maternal and paternal education on child nutrition weakened and remained statistically significant only for models on paternal education in flooded communities, and marginally significant in non-flooded ( Table 2 ).

However, the relationship between radiologic response and location of tumors was statistically significant (Table 5 ), and time to progression was marginally significant according to the location of bone metastasis (Figure 2 ).

Separate analyses comparing non-hospitalized [ 21 , 30 ] (d = 3.8; SE = 2.0; Z-value = 1.9; p = 0.055) or hospitalized control groups [ 26 – 29 , 33 ] (d = -0.3; SE = 0.5; Z-value = -0.6; p = 0.538) showed a marginally significant increase in SOL in patients with stroke as compared to non-hospitalized samples.

In univariable analysis of RFS, age, clinical subtype, tumor grade, stage at diagnosis, administration of neoadjuvant or adjuvant chemotherapy and type of surgery were all significant or marginally significant predictors of outcome (Table 2 ).

While evidence is emerging that sleep duration is inversely associated with childhood obesity [ 22 – 24 ], the current study only found a marginally significant increased likelihood of being overweight/obese in boys and girls not sleeping a minimum of 11 hours at night on weekend days.

Merely marginally significant evidence for the association between rs719725 and CRA risk was observed in a case-control study [ 47 ].

Compared with those who neither smoked nor used NRT, the authors reported a marginally significant increased overall risk, with the adjusted relative rate given as 1.61 (95 % CI 1.01–2.58), which they suggested “needs to be replicated”.

No correction has been made for multiple testing, and so marginally significant results need to be treated with caution.

Regarding affective quality of the communication the analysis revealed a marginally significant direct association between unmet needs for affective quality (i.e., the affective quality of the communication was considered to be important but then not experienced) and less reduction of psychosocial problems after 1 year ( p = 0.06).

4a ), which, although marginally significant, is an order of magnitude lower than our mean rate for both fractions (see Supplementary Table 1 ) and an order of magnitude greater than that determined with an ultrasensitive STOX sensor for raw, unadulterated, or non-concentrated, seawater of up to 0.085 μmol l −1 h −1 (ref. 65 ).

Table 5 showed a marginally significant interaction of EC and CC when comparing current versus never smoking (95% CI: 0.20–1.07).

However, when we tested for the origin by offspring environment interaction within each parental environment, the interaction was significant when parents were grown in 0mM NaCl ( Fig 1C ), and marginally significant when parents were grown in 100mM NaCl ( Fig 1D ).