Barely Significant
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near-significant

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Listed by Otte et al. (2022)

In the literature

near-significantp = 0.091.8× alphagold
tive quadratic term that did not reach statistical significance at the α = 0.05 level (OR = 0.00, 95% CI: 0.00–0.92, p = 0.06), and the core risk factors for CKM multimorbidity in this region included age, CESD-10 score, and baseline BMI; in cold regions, the linear term of the association showed a near-significant positive trend (OR = 1.56, p = 0.09), with no statistically significant effects observed in RCS interaction terms, and the core risk factors were age, CESD-10 score, and household registration type (OR = 1.87, p < 0.001); In temperate regions (central cities), RCS analyses showed no statistically s
near-significantp-value = 0.0924891.8× alphagold
The association between GLP-1 receptor agonists and osteoporosis with pathological fractures was significant in the IVW analysis, yet the Q test in MR Egger regression indicated near-significant heterogeneity (p-value = 0.092489) ( Table 4 ), suggesting potential heterogeneity among instrumental variables for this association.