“near-significant”

This near-significant pattern is consistent with the expected biomechanics of raised intracranial pressure: the ONS serves as a distensible CSF-filled compartment and therefore expands early in the course of ICP elevation.

This near-significant result strengthens the conclusion that tracer behavior is an important factor to consider in predictive models.

Other phenotypes, such as > 160/≤88 mmHg and > 160/>100 mmHg, showed significant or near-significant associations in several adjustment models but exhibited wider confidence intervals in the final model, potentially due to smaller subgroup sample sizes or treatment bias.

Although the majority of kittens in the study (regardless of treatment, age or disease severity at study entry) achieved the defined resolution or recovery endpoints, kittens receiving famciclovir along with antibiotics had a number of statistically significant or near-significant outcomes superior to those seen in kittens receiving antibiotics only.

Focal players with a higher skill achieved relative to the experimental player also made more positive comments (β = 0.29, χ 2 = 5.12, p = 0.02); there was a near-significant interaction with manipulation such that the experimental player in the female-voiced treatment received more positive comments when focal players were of a higher skill level, but fewer positive comments when the experimental player was higher in skill ( Fig 2 ).

The near-significant difference raises the possibility that expanding the sample size could enhance statistical power to confirm this association—however, this remains speculative and requires validation in larger, multi-center cohorts.

In this analysis, near-significant mediation effects were observed for connectivity between CA1 and the individual retrosplenial parcels (bilateral Rsp1 and Rsp2), approaching significance ( p ( a × b ) < 0.05, Table S10 ).

A valuable approach to improve statistical rigor would be to re-examine these near-significant miRNAs in expanded populations to evaluate their reproducibility and potential additive effects when analyzed in combination.

The near-significant between-strain difference under high-illumination conditions further implies that genetic predisposition to hypertension influences autonomic responses to environmental stimuli, with SHRs consistently exhibiting higher sympathetic predominance than do their normotensive counterparts.

Conclusion One month after high-dose vitamin A supplementation, serum retinol concentrations did not increase significantly; however, the RID technique showed near-significant increases in TBS and TLR.

However, the near-significant p -value and the magnitude of discrepancy in some cases may reflect the operator-dependent nature of ONSD ultrasound.

Two SNPs in AA (SNPs 4 and 5) and three SNPs in EA (SNPs 4, 5, and 7) showed significant or near-significant effects ( Table 3 ).

Follow-up comparisons within the left IFG cluster showed a near-significant priming effect in the higher predictive validity blocks (Z = 2.67, p FWE = 0.054).

Possibly, we failed to find an error rate switch cost in the MDD group because these patients tended to slow down their responses on SEs, resulting in a near-significant RT difference between MDD and controls on SEs.

The near-significant trend between visual methods and IOCs may suggest a marginal advantage in SE for IOCs, potentially reflecting improved surface-level visualization due to digital magnification or real-time imaging.

In group E, Succinivibrionaceae UCG-001 ( p = 0.063) and Christensenellaceae R-7 group ( p = 0.057) showed near-significant shifts between periods.

However, an early small study suggested a near-significant 50% decrease in methylprednisolone clearance in blacks [ 26 ].

The results indicated that there were significant and near-significant differences in the cortical bone between these two strains.

Western blot densitometry data for NRAS, ZAP70 and TFAM are consistent with the mass spectrometry data with significant or near-significant trends detected ( Figure 7 ).

Only variables that showed significant or near-significant differences between ERI groups in univariate comparisons were considered for inclusion in the regression models.

Per-protocol analysis for Modulen group ( n = 11): Per-protocol analysis of 11 patients who completed eight weeks of nutritional treatment confirmed significant improvements in CDAI, IBDQ, and a near-significant improvement in total symptoms score.

There are indications that the probiotic supported such a transition, with CST 1 showing a near-significant association with the probiotic group.

Receiving auditory feedback was associated with a near-significant 15% increase in correct breath counting, suggesting improved state mindfulness.

The near-significant associations of these functionally relevant genes suggest that they may contribute to OCD pathophysiology through disrupted ion channel function and neuronal excitability.

Conclusion Higher CCD improves DMFS in LA-NPC patients with IMRT, with a near-significant OS trend.