“nominally significant”

The linear effect for Existence was nominally significant, b = −0.107, p = .037, but was not significant after FDR correction, p FDR = .130.

A nominally significant association with bleeding risk persisted only for rosuvastatin (OR = 2.189; 95% CI: 1.039–4.612; p = 0.037), but this finding should be interpreted with caution and regarded as exploratory. 3.4.

Perhaps in line with this idea, we did see a nominally significant benefit of vitamin D on biological age ( p = 0.037) before correcting for multiple testing.

A nominally significant interaction effect was observed in patients with hypertension ( P = 0.037) and in those with wide QRS ( P = 0.003) ( Table 6 ).

Similarly, the conditional multivariable MR association of IL-6 on AN is only nominally significant (OR = 0.96, [95% CI = 0.93–0.99], P = 0.037).

An initial synthesis of the volume data from the left and right habenula using a paired samples t ‐test also supported this point: no significant interhemispheric differences for either the healthy samples ( t (24) = 1.443, p = .162, Cohen d = 0.289), or the patients with SCZ ( t (4) = −0.550, p = .612, d = −0.246); there appeared to be a nominally significant difference in MDD subgroup ( t (10) = 2.403, p = .037, d = 0.725), but it did not survive correction of multiple testing.

In contrast, the probabilities of transitioning from other PL states to PL state 3 were all increased, with the transition from PL state 4 to PL state 3 also showing a nominally significant difference (uncorrected p = 0.0376, Cohen’s d = 0.5201).

Among diabetic patients, a nominally significant difference in unadjusted event rates was observed (12% vs. 35%, p = 0.038), though this exploratory subgroup analysis requires cautious interpretation given the small sample and absence of adjustment for confounders. 4.1.

Longitudinal stratification of the CIPN phenotypes to examine links for neuropathy, identified nominally significant protective associations with the GSTM* null allele ( p -value = 0.038, OR = 0.55) and the presence of pain at month 2 of treatment, as well as a risk factor for pain related month 2 of treatment for individuals with the GSTT1* null allele ( p -value = 0.030, OR = 1.64).

When tested individually, both di- and tetranucleotides showed at least nominally significant signals (two-sided z -proportion test P = 0.038 and P = 3.7 × 10 –38 , respectively), but trinucleotides did not ( P = 0.95).

PERMANOVA analyses identified nominally significant effects of Age within the ONT dataset at the phylum (R2 = 0.204, p = 0.038), family (R2 = 0.154, p = 0.020), and genus (R2 = 0.139, p = 0.029) levels, whereas no nominally significant effects were detected in the Illumina dataset (Supplementary Table S2).

Although the analysis of the original four-category scale produced a nominally significant result (χ 2 = 8.45; p = 0.038), more than one-third of cells (37.5%) had expected frequencies below 5.

Additional sensitivity analyses showed that the cML-MA-BIC-DP method (OR 0.60, 95% CI 0.53–0.69, p = 3.85 × 10 −11 ) yielded a similar result to IVW and weighted median methods ( Table 5 ), while the association from MR-APSS method was nominally significant (OR 0.20, 95% CI 0.05–0.92, p = 0.038) ( Table 5 ; Supplementary Figure S2 ).

MR pleiotropy residual sum and outlier (MR-PRESSO) test identified 5 outliers for IBD, 1 for RA and 2 outliers for vitiligo ( Table S10 ), whereas exclusion resulted in a nominally significant association for vitiligo (OR, 95% CI: 0.827, 0.691–0.989), p -value = 0.038; Figure 4 a).

For those who identified as Southeast or South (SE/S) Asian, there was a nominally significant interaction ( p = 0.039; β = 0.358) with religious attendance ( Fig. 3 ).

For the hyperactivity/impulsivity subscale, no significant group × time interaction effects were observed at any assessment point except T2, where a nominally significant group × time effect was found ( b = -1.766, t = -2.066, p = 0.039); however, this result did not remain significant after FDR correction.

For the OR, FA showed a nominally significant negative association at the uncorrected level (β = − 0.187, t (110) = −2.084, p =.039), but this did not survive FDR correction (FDR adjusted q = 0.118).

Nominally significant positive associations were observed between the weighted PGS and maternal alcohol consumption at week 30 (ST17; beta = 0.067, se = 0.032, p = 0.039).

Reverse MR suggested nominally significant associations: higher genetically predicted heel BMD was associated with lower POI risk ( OR = 0.792, 95% CI : 0.635–0.988, P = 0.039), while genetic susceptibility to wrist fracture ( OR = 1.44, 95% CI : 1.038–1.986, P =0.025) and pelvic fracture ( OR =1.177, 95% CI :1.056–1.312, P =0.003) were associated with increased POI risk.

At a threshold of FIS ≥0.7, SERPING1 variant carriers had a nominally significant increased risk of NCEIS (HR, 3.29; 95% CI, 1.06-10.19; P = .039) and PAD (HR, 3.10; 95% CI, 1.29-7.45; P = .011), with the association for PAD remaining significant after Bonferroni correction ( Figure 2 C; supplemental Table 4 ).

Left VAN showed a nominally significant difference ( p = 0.039) that did not survive FDR correction (p~FDR~ = 0.110) and is therefore not considered a statistically significant finding.

0.25), corresponding to a nominally significant association (OR = 1.68; 95% CI: 1.05–2.67; p = 0.039).

The difference in lymph node reduction between groups had nominally significant association in this exploratory analysis (p = 0.039, independent-samples t -test), with a moderate-to-large effect size (Cohen’s d = 0.71) ( Figure 2 ).

69 In the phase 3 CUPID B trial that investigated patients with CSU who were refractory to 3 months of omalizumab therapy, a nominally significant reduction in UAS7 from baseline compared with placebo (−14.4 vs −8.5; P =0.0390) was observed at week 24.

Assessment for significance of an SOD2 (# Ala16 alleles)-by-deployment interaction term (adjusted for both components of the interaction) to evaluate for effect modification by deployment was nominally significant, p = 0.039.