“nominally significant”

However the distribution of CCT across three bins was nominally significant ( P = 0.049), with the largest fraction of V83I patients having CCT greater than 540 μm.

1 C); with a nominally significant increase in the non-delirious group (median increase of 11.4%, 95% CI: 0.0%–23.5%, p = 0.0491).

There was a nominally significant association between the s allele of the 5-HTTLPR polymorphism and TEM (odds ratio, 1.434; 95% confidence interval, 1.001–2.055; P = 0.0493; I 2 = 52%).

In uncorrected pairwise comparisons, only the proportion of activated NK cells showed a nominally significant difference between the IDD and control groups (raw P = 0.04949).

Additionally, there was a nonsignificant trend towards multiple repeat mutations (p = 0.5127), as well as, a nominally significant trend towards deletion mutations (p = 0.0495) (Table 6 ).

A nominally significant association with BPD was found for rs1006737 in CACNA1C ( P =0.0498).

Finally, we found significant differences in the frequencies of TAGA ( P = 0.005, OR = 3.187, 95% CI 1.376–7.382) containing rs4570625-rs11178997-rs1386494-rs7305115 between ODD and control groups (Tables 7 , 8 ). However, the further analysis by Haploview revealed the nominally significant finding for rs1386494 ( χ 2 = 3.846, P = 0.0499), and only one haplotypes (TAGA, χ 2 = 4.366, P = 0.0367) remained significant.

18 Nevertheless, considering the sample size limitations, throughout the manuscript we show nominally significant results as p≤0.05 and results significant after adjustment for multiple testing as FDR≤0.05.

Gene-based analysis revealed 76 nominally significant ( p ≤ 0.050) longevity-associated genes, and we call these 76 genes the “longevity-associated gene set” (Tables S3 and S4 ).

Eleven out of the 16 SNPs in this genomic area are nominally significant (10 −6 <p<.05) providing additional support for the involvement of EFNA5 in AD.

Of these, 10 had significantly different effect sizes ( p -value < 7.8 × 10 −4 , Bonferroni correction for 64 variants) and 22 were nominally significant ( p -value < 0.05).

Although we reported nominally significant results ( p < 0.05) to maximize sensitivity for hypothesis generation, these results should be interpreted with caution until replicated in larger cohorts and MCC.

Differences between groups were nominally significant (nominal P < 0.05) if the 95% confidence interval [CI] of the group difference did not include the null value (0 for mean differences and 1 for odds ratios), but for the sake of convenience, if the nominal P ‐value in the secondary analysis is less than 0.05, it is described as significant, and if it is 0.05 or more, it is described as non‐significant.

Also, the association between sentinel variants in the FoxP1 gene and diagnosis of IPF was nominally significant ( p < 0.05) rather than genome-wide significant.

36 All available 29 WMH burden risk variants showed nominally significant association with extreme-SVD ( P -value < 0.05), with 26 associations remaining significant after multiple testing correction ( P -value < 1.79 × 10 −3 ; Supplementary Table 6 ).

Specifically, we identified a total of 169 nominally significant enriched terms ( p -value < 0.05 and FDR < 0.2), which represent a medium-confidence set, including a subset of 37 high-confidence terms that passed multiple test correction with an FDR of <0.05 ( Figure 3 ).

In a per-protein analysis, replacing values below the limit of detection with protein specific LOD-values, five proteins (CSF-1, NTRK3, ICOSLG, SCF and PECAM-1) were found to have nominally significant differences between the two time-points (p < 0.05, Wilcox test).

In the hDRG, hPEP.PIEZOh, hNP1, and hTRPM8 were nominally significant ( P < 0.05) cell types among females, and hPEP.TRPV1/A1.2, hAδ.LTMR, and hTRPM8 were nominally significant among males, though none of these cell types was significantly enriched after correction for multiple testing ( Supplemental Figure 1B and Supplemental Table 12 ).

A total of 19 HLA alleles had nominally significant maternal and/or fetal effects on BW ( P <0.05; Supplementary Table S7 , available as Supplementary data at IJE online); 13 of the 19 alleles had evidence for a maternal effect only, four alleles primarily had evidence for a fetal effect only and two alleles had evidence of both.

Fourteen MGSs were nominally significant for the broad spectrum (Wilcoxon signed-rank test, unadjusted p < 0.05).

To verify the reliability of these polygenic associations, we repeated the analyses using PRS comprising only the 108 sentinel genome-wide significant schizophrenia variants 15 , based on the assumption that the effect size estimates of genome-wide significant variants should be less affected by population structure than non-significant variants; 77 of the 104 associated traits were nominally significant ( P < 0.05) based on the PRS comprising only genome-wide significant variants.

Variable Selection Based on linear mixed models including the factors of time, age at enrollment, sex, and stimulus version, 23 speech variables from the picture description task showed nominally significant ( P < 0.05) effects of time at the group level.

Seven genera showed nominally significant IVW associations with endometriosis ( P <0.05): Lactococcus , Olsenella , Senegalimassilia , Ruminococcaceae UCG-002, Holdemania , Eubacterium ruminantium group and Anaerotruncus .

While none of the GO terms from the trio univariate GSEA met the FDR significance threshold, nominally significant (p < 0.05) pathways suggest some overlap with Cohort 1 results, including neuron recognition , cerebral cortex cell migration and axonal fasciculation and GO terms related to.

Multivariable modelling and the relations between predictor variables All predictor variables having shown nominally significant (p < 0.05) effects on hand preference in univariable testing (i.e. all but maternal smoking) were then included in the multivariable analysis, using general linear modelling (Methods), with hand preference as the dependent variable.