“showed a trend”

The sequential use of Afatinib followed by Osimertinib showed a trend toward improved OS, highlighting the importance of rebiopsy for identifying T790M mutations to guide subsequent therapy.

Patients who achieved CR to glofitamab also showed a trend toward a higher percentage of CD8+ T-cell infiltration in the TME [ 49 , 51 ].

While continued anticoagulation showed a trend toward lower stroke risk, this difference did not reach statistical significance.

The total phenols, flavonoids, DPPH, and FRAP showed a trend of small inheritance in the leaves.

While systolic blood pressure showed a trend toward higher values in the obese group (101.77 ± 23.88 mmHg) compared to the non-obese group (97.16 ± 15.88 mmHg), the difference was not statistically significant ( p = 0.06).

The results of these studies were similar to our observation, as they showed a trend of a significant increase in salivary CRP values in OPMD and malignancy patients compared to healthy controls, similarly to our study [ 10 , 15 ] However, the CRP values recorded in our study could not be correlated directly with the previous studies’ results due to the different laboratory techniques and working principle employed.

The distribution of the WHO ordinal scale classification showed a trend that SIR1-365 increased the percentage of patients with ambulatory mild disease and decreased the percentages of hospitalized patients with moderate or severe disease, compared with placebo ( Figure 2 ).

Moreover, somatic mutation of GNAS (p = 0.0565), KMT2D ( p = 0.0565), and TP53 ( p = 0.0854) showed a trend to be correlated with ORR ( Figure 2 B).

After 50 non-hemorrhagic cases, the overall AUC values showed a trend of gradually increasing to 150 non-hemorrhagic cases ( Figure 4 B).

The protein expression levels of the three genes were subsequently analyzed using Western Blot, which showed a trend consistent with the qPCR data ( Fig. 3 B).

In CFA3D, PRE-084 showed a trend toward hyperpolarizing the threshold, although this effect did not reach statistical significance ( p = 0.09, Figure 6 C).

For the OS, a PR-positive status showed a trend toward reduced mortality risk compared with the PR-negative patients (HR, 0.61; 95% CI, 0.30–1.24), though this did not reach statistical significance ( p = 0.173).

Furthermore, cells showed a trend of decreased viability and increased IL-8 secretion upon nanoTiO 2 deposition, indicating potential for application.

BnBBR-BPC3 showed a trend of initial downregulation followed by upregulation, while BnBBR-BPC15 exhibited an initial upregulation followed by downregulation.

Concurrently, the rapid death rate in the empty vector group led to a swift increase in free proline, which showed a trend of surpassing that of the transgenic group.

Neck positioning in a neutral position showed a trend toward improvement, with 5 participants reporting a decline, 13 showing improvement, and 92 reporting no change, though the result was not statistically significant (Z = −1.886, p = 0.059).

43 Using proteomics and network analysis to assess vein graft kinetics in mice, Decano et al., showed that tricarboxylic acid substrate utilisation of α-ketobutyrate showed a trend of increasing rate on pemafibrate treatment and reversal on PPARα (peroxisome proliferator-activated receptors) silencing resulting in less vein graft lesions and failure. 44 Recently, Wu et al., reported that exogenous alpha-ketobutyrate supplementation promoted longevity and delay senescence in fibroblast cells via augmentation of NAD + and perioxosome biogenesis in C. elegans via the SIRT-NRF2 pathway. 45 It is, thus, plausible that alpha-ketobutyrate levels may form a favourable equilibrium between oxidative stress response and endothelial injury.

The content of endogenous hormone GA 7 in the tillering node of SN28 and TN18 showed a trend of rapid increase followed by a slow decrease as the growth stage progressed, reaching a maximum during the GS20 stage.

At a uniform nitrogen application rate, the WUE of eggplants showed a trend of increasing and then decreasing as water deficiency intensified, with the W 2 level achieving the highest WUE.

Guo and Zhang [ 10 ] reviewed and revealed that by participating in the AV tester program, AV manufacturers showed a trend toward improvement in their AV technologies (e.g., an 8% decrease in the number of disengagements caused by hardware and software discrepancies and a 12% decrease in the number of disengagements caused by perception discrepancies).

At the same time, the health evaluation results of the chemical–biological integrated index in the period of 1998–2022 showed that the health status of the eleven key sections in Poyang Lake showed a trend of the first quarter > fourth quarter > second quarter > third quarter.

For inflammatory markers, the G28083T mutation was associated with decreased levels of CRP and LDH, showing a trend ( p < 0.1), whereas the C25904T mutation showed a trend toward increased IL-6 levels, which could suggest mutation-related impacts on inflammation, albeit without statistical significance.

In contrast, the GSH and GSSG contents showed a trend of first decreasing and then increasing, both reaching their lowest levels under the T3 treatment at 479.31 nmol·g −1 and 998.15 nmol·g −1 , respectively, being 75.91% and 38.51% lower than those under the SA treatment.

After five administrations, paw volume measurements also showed a trend consistent with arthritis scores.

The average fruit weight showed a trend similar to the changes in total fruit weight.