Barely Significant
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“showed a trend”

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In the literature

In the left ATR, for controls, R2* was weakly to moderately negatively correlated with FA (r = –0.129, p-adj < 0.001) and RD (r = –0.100, p-adj = 0.011), and showed a trend-level negative association with AD (r = –0.072, p-unc = 0.026, p-adj = 0.077), while no significant correlation was found with MD (r = 0.046, p-adj = 0.301).
25 , 63 A study showed a trend of V12 associated with increased toxicity risks, and a high rate ( ∼ 50%) of toxicity with V12 >10 cm 3 . 36 , 64 However, these reports established values considering mainly SRS plans in machines like Gamma Knife, where the considerations may differ from a linear accelerator.
While MEKiAUTO ( NCT04214418 ) showed the combination of mitogen-activated protein kinase kinase inhibitor (MEKi) cobimetinib, HCQ, and PD-L1 inhibitor Atezolizumab demonstrated limited tolerability and efficacy in patients with advanced KRAS-mutated pancreatic ductal adenocarcinoma, clinical benefit was observed in 36% of patients, while all of whom achieved stable disease as their best response; and patients with KRAS G12R mutations showed a trend toward improved overall survival (OS) compared to those with KRAS non-G12R mutations ( 77 ).
The multiple comparison of the time spent in close interaction during the social novelty phase showed a significant preference for the new unfamiliar mouse compared to the familiar one in HTZ adult females, whereas WT females showed a trend toward preference for the new unfamiliar mouse (100.1 ± 10.0 s HTZ with unfamiliar; 60.1 ± 6.6 s HTZ with familiar; 62.3 ± 5.2 s WT with unfamiliar; 41.5 ± 3.5 s WT with familiar; two‐way ANOVA, F (1.44) = 20.19, p < 0.0001 for cylinder effect, F (1.44) = 17.47, p = 0.0001 for genotype effect and F (1.44) = 2.016, p = 0.1627 for genotype × cylinder interaction; Sidak's post hoc test: WT familiar vs. unfamiliar p = 0.19, HTZ familiar vs. unfamiliar p = 0.0008, WT unfamiliar vs.
Overall, the GAD group showed a trend of increased ΔHbO in the left VMPFC, right VMPFC and right DLPFC and decreased ΔHbO in the left DLPFC and right DMPFC from baseline to task, whereas the healthy controls exhibited increased ΔHbO across the bihemispheric PFC, particularly in the left VMPFC, right VMPFC, right DLPFC, and right DMPFC. 3.3.