In the left ATR, for controls, R2* was weakly to moderately negatively correlated with FA (r = –0.129, p-adj < 0.001) and RD (r = –0.100, p-adj = 0.011), and showed a trend-level negative association with AD (r = –0.072, p-unc = 0.026, p-adj = 0.077), while no significant correlation was found with MD (r = 0.046, p-adj = 0.301).
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In the literature
25 , 63 A study showed a trend of V12 associated with increased toxicity risks, and a high rate ( ∼ 50%) of toxicity with V12 >10 cm 3 . 36 , 64 However, these reports established values considering mainly SRS plans in machines like Gamma Knife, where the considerations may differ from a linear accelerator.
found that the majority of cancer patients with low or moderate FCR levels showed a trend toward resolution over time [ 18 ].
In addition, a visual scoring system devised to grade callus showed a trend towards improvement in the treated cohort [ 13 ]. 3.4.
While MEKiAUTO ( NCT04214418 ) showed the combination of mitogen-activated protein kinase kinase inhibitor (MEKi) cobimetinib, HCQ, and PD-L1 inhibitor Atezolizumab demonstrated limited tolerability and efficacy in patients with advanced KRAS-mutated pancreatic ductal adenocarcinoma, clinical benefit was observed in 36% of patients, while all of whom achieved stable disease as their best response; and patients with KRAS G12R mutations showed a trend toward improved overall survival (OS) compared to those with KRAS non-G12R mutations ( 77 ).
The multiple comparison of the time spent in close interaction during the social novelty phase showed a significant preference for the new unfamiliar mouse compared to the familiar one in HTZ adult females, whereas WT females showed a trend toward preference for the new unfamiliar mouse (100.1 ± 10.0 s HTZ with unfamiliar; 60.1 ± 6.6 s HTZ with familiar; 62.3 ± 5.2 s WT with unfamiliar; 41.5 ± 3.5 s WT with familiar; two‐way ANOVA, F (1.44) = 20.19, p < 0.0001 for cylinder effect, F (1.44) = 17.47, p = 0.0001 for genotype effect and F (1.44) = 2.016, p = 0.1627 for genotype × cylinder interaction; Sidak's post hoc test: WT familiar vs. unfamiliar p = 0.19, HTZ familiar vs. unfamiliar p = 0.0008, WT unfamiliar vs.
Notably, the ORs of the sarcopenia-obesity group showed a trend of “decreasing and then increasing” (4.206→2.667→3.368), suggesting that the risk of this phenotype is driven by the synergistic effect of body composition abnormalities and metabolic disorders.
( 116 ) found that AEBS did not exhibit significant inhibition of the NF-κB signaling pathway in a CIA mice model, although it showed a trend towards inhibition.
Notably, quadriceps and tibialis anterior mass showed a trend of improvement but did not reach statistical significance ( Fig.
Compared with the VS group, the VF and LLV groups showed a trend toward increased use of the NRTI+PI/r regimen in their current ART regimens, although the difference did not reach statistical significance.
The use of aminoglycosides and carbapenems showed a trend towards increased pain scores, although statistical significance was not achieved.
Overall, the GAD group showed a trend of increased ΔHbO in the left VMPFC, right VMPFC and right DLPFC and decreased ΔHbO in the left DLPFC and right DMPFC from baseline to task, whereas the healthy controls exhibited increased ΔHbO across the bihemispheric PFC, particularly in the left VMPFC, right VMPFC, right DLPFC, and right DMPFC. 3.3.
The CDDP group exhibited a statistically significant decrease in mouse body weight, whereas CDDP-KA combination therapy showed a trend of weight recovery in mice [Supplementary Figure 8C, http://links.lww.com/CM9/C458 ].
Body mass index (BMI) distribution showed a trend towards higher measures (≥ 30) in the DE group (94.4%), although this was not statistically significant ( p = 0.175).
Compared with the fresh catalyst, the specific surface area of RZ409 catalysts used at different reaction temperatures all decreased, and showed a trend of gradually decreasing with the increase of reaction temperature.
Moreover, positive PD-L1 expression showed a trend for improved OS (Supplementary Fig.
Unexpectedly, the results showed a trend towards a lower risk of progression in the capped patient groups.
hawaiensis showed a trend towards decreased production when fed dried U. lactuca meal in place of a pelleted shrimp diet, but significant lower densities were only noted in the adult population 23 .
S12a–d ), for instance, paralleled these of human adipocytes with impaired OLFM2, which showed a trend towards the overrepresentation of thermogenic genes (Fig.
Conclusion HCQ therapy for primary glomerular diseases showed a trend toward reducing proteinuria without significant effects on eGFR, with a better safety profile.
Overall, the mean (± SD) change from baseline to Month 6/EOS was − 0.027 ± 0.171 m/sec, which showed a trend towards deterioration, but was not statistically significant ( p = 0.064).
However, the genus Coccidioides had the highest relative abundance in the control group and showed a trend of increasing first and then decreasing with the increase in drought treatment intensity.
However, the present study showed a trend indicating different novel predictive biomarkers for anti-IL-6R and anti-TNF-α treatment response.
The antioxidant activity of wines determined by the DPPH assay showed a trend somehow similar to those observed so far.
In the fully adjusted model, compared to those who never/rarely added salt to foods, participants who always added salt showed a trend toward higher FIB-4 scores (β = 0.37, 95% CI: 0.03–0.70), although this did not reach statistical significance for the continuous outcome.