Barely Significant
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“showed a trend”

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In the literature

In contrast, neither poly-SUD nor the A1 allele of the Taq1A polymorphism showed an independent association with mortality, although the genetic effect showed a trend towards significance, suggesting that Taq1A genetic variation may modestly contribute to adverse outcomes in AUD.
In CD, patients with SES‐CD < 3 or absence of ulcerations were paradoxically less likely to have met targets by Week 26, whereas in UC, achieving targets by Week 26 showed a trend toward better endoscopic outcomes (Table 2 ). 4 DISCUSSION Based on updated STRIDE‐II recommendations, we analyzed outcomes of pediatric IBD patients during the first year post‐diagnosis in a real‐world setting, assessing time to clinical, fecal, and serum biomarker remission as well as relapse.
Interestingly, while not reaching strict statistical significance, the high-risk group showed a trend toward enrichment in the “extracellular region part” pathway, suggesting a potential role for transmembrane proteins and extracellular matrix remodeling in this aggressive phenotype, though further validation is required.