Mitochondrial genes mtNd4l, mtNd5, mtAtp6 and mtRnr1 as well as nuclear genes Gja1 and Sfrp4 showed similar expression in both controls and lean PCOS groups, and Xrcc1 showed a trend in lower abundance that did not reach statistical significance (Data not shown).
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At P16, Vhl MCΔ/Δ retinas showed a trend to have reduced numbers of myeloid positive cells (Fig. 3 a).
Analysis of microbial composition of wastewater of Elizabeth’s shaft showed a trend to increase the abundance of tolerant bacteria leading to a reduction of the total bacterial diversity.
The subgroup analysis was performed according to the ranges of AFC, patient's age, and stimulation protocol in Table 5 , in which the CLBR showed a trend similar to the general trend in all subgroups with the addition of women over 35.
The FFMQ total scores only showed a trend for significantly explaining higher levels of trait anxiety when controlling for the effect of SCS total scores (by entering the FFMQ total scores in the second step).
26 In the EXAMINE study, patients with recent acute myocardial infarction treated with alogliptin also showed a trend of slight increase in admission to hospital for HF, although not statistically significant [hazard ratio (HR) 1.19, 95% CI 0.89–1.58, P = 0.22]. 27 On the contrary, the VIVIDD study, which evaluated the effect of vildagliptin on ventricular function in HFrEF diabetic patients with NYHA Fc I to III
Our study found that SCUBE3 also showed a trend of overexpression in Her2-positive breast cancer, and the related mechanism of its participation in this progression needs to be further explored.
As the result, the mRNA levels of IL-17 cytokines family were significantly upregulated after 10 μg/ml LPS challenge, and their expression levels generally showed a trend of first increasing, then decreasing, and finally stabilizing with the increasing of LPS concentration (Fig. 6 ).
This could be shown by the finding that mice injected with sitagliptin treated bacteria showed a trend for better survival compared to mice injected with DMSO treated bacteria or untreated bacteria.
The first two large RCTs showed a trend towards a decrease in foetal metabolic acidosis (only being significant in the first one) and a significant decrease in the rate of operative delivery for foetal distress when using the STAN ® -method compared to the use of CTG alone ( Westgate et al. 1993 ; Amer-Wåhlin et al. 2001 ).
The heat-killed cells showed a trend of AUC glucose elevation at the higher dose ( Fig. 4B ).
• Both high (1000 nmol/kg) and low (100 nmol/kg) doses only showed a trend in functional improvement.
OS also showed a trend that favored continuous nivolumab.
Effects of the resident workshop Residents’ teaching effectiveness and their impact on students’ rotation experience showed a trend of increase after the workshop, but this did not reach statistical significance ( p = 0.35).
Our study first of all showed a trend for an increase in stiffness over time, which is not surprising.
Caribbean women showed a trend towards greater odds of functional limitations than White British women throughout adulthood, while African women demonstrated higher odds after early adulthood.
Spinach and clover showed a trend of increasing Cd from roots to the leaves, above-ground.
Plasma IL-12, IL-23, IL-27, and IL-35 Levels Were All Closely Associated with the Presence of CAP The clinical characteristics, including male gender, elderly, overweight, smoking, drinking, nondipper, T2DM, HLP, SAHS, hypoxemia, CRP, tHcy, and the IL-12 members, were used to perform univariate analysis, and the results showed that IL-12, IL-23, IL-27, IL-35, male gender, elderly, overweight, drinking, nondipper, T2DM, HLP, SAHS, hypoxemia, and tHcy showed a trend.
On the contrary, in the large nonrandomized registry, the Coronary Revascularization Demonstrating Outcome (CREDO)-Kyoto Registry Cohort-2 [ 43 ], prolonged thienopyridine therapy beyond 1 year did not reduce ischemic events, but showed a trend toward increased bleeding.
Han (2019) analyzed the temporal and spatial evolution characteristics of China’s marine fishery ecological efficiency from 2006 to 2015, the results showed that the average value of marine fishery eco-efficiency in China was at a moderate level and fluctuating downward, while the regional differences showed a trend of fluctuation and expansion [ 17 ].
Comparisons between the two groups showed a trend towards older age in patients with bone invasion.
In the neoadjuvant chemotherapy subgroup, the PFS and OS curves after 20 and 30 months respectively showed a trend towards gradual distinction favoring HIPEC, allowing the authors to conclude that more long-term follow-up is needed to confirm the impact of HIPEC in this population [ 35 ].
In our series, a high variability in antibodies titers at baseline was shown; however, most patients showing a protective titre against the tested agents showed a trend to maintain it.
For the inter-day reliability, all ICC values were higher than 0.8 and the 95% CI also showed a trend of (ICC+0.2; ICC−0.2), except for rotational range of the CP group (ICC = 0.53) with a wide 95% CI.
Compared to sham animals, animals receiving 15%, 30% and 45% erythrocyte transfusion showed a trend to increase in dry:wet ratio over sham, however these changes were not statistically significant ( Fig 6B ).