“showed a trend”

We demonstrated by several methods that ALP levels were elevated in BMSCs expressing the miR-320a inhibitor compared with the control cells, and BMSCs with miR-320 overexpression showed a trend in the opposite direction.

The resulting BT diagnostic models all yielded AUCs higher than 0.93, and the stepwise selection method showed a trend of lower AUC than LEfSe analysis for their given models (Fig. 4a ).

In the analysis for TIM3, CAR-αPD-1 and CD19 CAR-Trap showed a trend toward the inhibition of TIM3 upregulation, but it did not reach statistical significance ( Figure 5 D).

The use of belimumab, a BAFF inhibitor, showed a trend to reduce naïve B cells, circulating plasmablasts, and memory B cells in adult KT recipients ( Banham et al., 2018 ).

Nonetheless, all of these reports showed a trend of better visual outcome in those receiving the implant.

However, efficacy analysis, despite not reaching statistical significance, showed a trend towards superiority of natalizumab over placebo: reduction in Crohn’s Disease Activity Index (CDAI) was numerically higher in the natalizumab group at week 6 (–37.7 points in the natalizumab group versus + 3.5 in the placebo group, p = 0.084). 89 As this study was not meant to prove efficacy, and we cannot know whether three additional infusions of natalizumab are actually sufficient to provide any significant benefit, this study only suggests the potentiality of add-on and temporary DTT.

Speech Intelligibility in Noise Four studies measured speech intelligibility in noise, and all showed a trend of a better outcome with REM fitting.

[ 2 ] This comparison of multiple three-drug regimens found that groups using oxaliplatin or capecitabine, rather than cisplatin or 5-Fu, showed a trend toward longer overall survival and improved safety.

Lesioned animals injected with tgfb3 haCRs showed a trend towards an increase in neutrophil counts of 23% compared to lesioned controls, but this did not reach significance (p > 0.05; Fig 3A and 3C ).

Antibody inhibition of both IFN-I and TNF signalling significantly downregulated CD86 to a much greater level compared to each individual treatment in MDDCs ( Fig 2C , right panel) and MDMs ( S2B Fig ) while CD80 was significantly downregulated in MDMs and showed a trend towards downregulation with the combined treatment in MDDCs.

From 1986 to 2017, the ESI showed a trend of N, which indicated that the spatial structure of the landscape was more stable and ecological security was more reasonable due to the implementation of policies such as the return of farmland to forest and designation of red lines for ecological protection.

Fat fraction showed a trend for increase at 12w.

In a recent study conducted in obese subjects, a single dose of the bispecific anti-FGFR1/KLB agonist antibody, BFKB8488A showed a trend toward reduction in preference for sweet taste and carbohydrate intake [ 98 ].

HCA showed a trend that the TCA cycle intermediates and amino acids accumulate in leaves, while sugars tend to accumulate in roots.

By analyzing the local cytokines, we found that the local pro-inflammatory factors also showed a trend of first increasing stage and then decreasing stage.

In general, the WT strain showed a trend to higher GalN relative abundance compared to Gal, whereas in the M1 ( barA ), M3 ( thyA ) and M8 (E1N14_01730) mutants the Gal content was highest (Table 2 ).

An analysis of candidate genes associated with DDR and PI3K/AKT/mTOR signaling showed a trend towards greater copy number amplifications in the PR group.

S 7 H showed a trend for the subgroup TP53(−) & ALG3(Low) but it was not significant for outcome after RT in the other subgroups, which was consistent with that both TP53 mutation [ 85 ] and ALG3 overexpression would significantly influence the radiosensitivity of breast cancer.

The choice of anxiolytic medication showed a trend toward a more frequent use of benzodiazepines in patients with agitation compared to all other patients (6/6 vs. 4/12), while low-dose morphine was used less frequently (2/6 vs. 7/12). 28-day-, in hospital- and 6-month mortality rates were 44% (8/18), 50% (9/18) and 50%, respectively.

Regarding total SCFA, the SYN and CTR− groups showed a trend for a decreased concentration compared to the other groups (P treatment = 0.085) at day 4 PI but not at day 8 PI.

In this model, MHCA showed a trend of protective effect on CMO (adjusted OR 0.6; 95% CI: 0.4–1.0).

Compared to wild type KRAS CRCs, KRAS mutated tumours showed a trend toward female patients (56.3% vs. 43.7%), patients with right-sided tumours (66.7% vs. 33.3%), and a moderately differentiated histology (53.6% vs. 46.4%).

However, there was a trend towards a difference in the number of deaths between the cohorts: the proportion of patients who died in cluster A was 43% (6/14 patients) compared to 19% in cluster B (7/37 patients, p =0.08). Methylation pattern is associated with a trend towards inferior outcome Estimate of overall survival using the Kaplan-Meier method showed a trend towards inferior survival for patients clustering in cluster A.

Assessing the configuration of the circle of Willis, missing segments of the anterior circulation (missing ipsilateral or contralateral A1 segment and/or missing Acom) showed a trend towards a significantly increased risk of a decline in intra-operative SEPs >0.5 without reaching the pre-defined level of statistical significance (OR 4.5, 95% CI 0.93–21.71, p = 0.061).

Those mothers who had been issued an infant soft structured carrier at birth were found to be more contingently vocally responsive and showed a trend toward being more sensitive toward their infant’s cues, state, and rhythm, as measured by the sensitivity-related scale from Crnic’s system ( Crnic et al., 1983 ), in comparison to the control group, which was issued a plastic seat.