“showed a trend”

This trend was not found in the control group, where CD4 + T cells kept an overall stable percentage over time, and CD8 + T cells showed a trend of increase in proportion over time that did not reach any significance ( Fig. 1D ).

The ALT level was also reduced with PEG-BR was not reduced but showed a trend toward reduction that did not reach statistical significance.

PC-mAb treatment showed a trend toward attenuated leukocyte infiltration in the infarct area and especially in the border zones (9.5 ± 1.6 leukocytes per 0.25 mm 2 and 4.2 ± 0.6 leukocytes per 0.25 mm 2 ; p = 0.153 and p = 0.080, consecutively).

The aTEHVs showed a trend of earlier and higher incidence of moderate valve regurgitation in time on TTE ( Figure 2M ).

The subgroup analyses showed a trend towards a higher risk of infection in the T/C group when restricting the analysis to those patients who were currently receiving therapy directed at their hematological malignancy, albeit not statistically significant.

It is noteworthy that the subgroup of patients with prematurely terminated isoflurane, and in particular those experiencing an elevated P aCO 2, had a significantly higher peak inspiratory pressure, lower lung compliance, and showed a trend towards higher ventilator minute volume in the period -24 h to -1 h prior to the implementation of the ACD when compared with the patients with continued isoflurane sedation ( Table 5 , Supplementary Table S1 ).

Interestingly, Hfe LysMCre mutant mice showed a trend towards a higher degree of induction of granulocyte colony-stimulating factor, interferon γ, interleukin (IL)-1b, IL-17α ( Online Supplementary Figure S2C ) and reduced induction of eotaxin, IL2, IL4, IL5, IL6, IL10, IL13, macrophage inflammatory protein 1α, and tumor necrosis factor α (TNF-α) mediators compared to control mice ( Online Supplementary Figure S2D ), raising the question of whether differential expression of these immune mediators may explain the remarkably higher tolerance of aged Hfe LysMCre mice to LPS-induced shock.

Conclusions With application of best practice as known by the time of the first three waves of the pandemic, our study failed to identify a significant improvement in mortality rate when comparing the different waves of the COVID-19 pandemic, notwithstanding, the sub-analyses showed a trend in mortality reduction in the third wave.

Conclusion This pilot showed a trend towards decreased inappropriate OPAT prescribing and cost avoidance of an ID pharmacist-driven review of OPAT prior to patient hospital discharge.

species in neonates showed a trend with C. tropicalis being more common C. species during the recent years.

109 In contrast, an initial trial in China involving 48 patients with moderate COVID-19 found that chloroquine (CQ) or HCQ showed a trend towards a decrease in the duration of hospital stay and lung computerized RCT. 110 Andrew et al (2020) also reported that HCQ significantly reduced the duration of hospital stay in a retrospective observational study. 111 Guérin et al (2020), in their initial study in France involving 88 patients,

8 In line with our results, pre-PCI TIMI flow was better in the lytic-facilitated PCI group, but contradictory with our study, the trial showed a trend to worse infarct size, more early and late microvascular obstruction (MVO) in cardiovascular magnetic resonance (CMR), and 30 days event rate in the lytic-facilitated PCI group.

A Scandinavian study showed a trend towards lower 1-year mortality with higher treatment volume for unruptured intracranial aneurysms, but not for ruptured ones [ 12 ].

Patients treated with proning showed a trend towards later intubation (median = 1 day), but no reduction in IMV or 28 day mortality.

The imaging positive yield showed a trend toward reduction (− 2.6%, 95% CI − 13.1; 8.0).

Furthermore, grading of the tumor sections by a clinical breast cancer pathologist showed a trend for increased numbers of proliferating tumor cells positive for nuclear Ki67 in MMTV-Wnt1-p75 +/− tumors ( Figure 2 F/G ).

aureus in the Ti6Al4V-6.5wt%Cu alloy showed a trend of decreasing ( Fig. 3 B), indicating Ti6Al4V-6.5wt%Cu alloy inhibited the activity of S. aureus at the early stage of bacterial adhesion and accelerated its aging and death at 6–8 ​h.

The capacity retention rate of the FEMC-Elect has also showed a trend of decrease, which may be related to its lower conductivity.

Insoluble PA, which exhibited markedly lower levels than soluble PA, showed a trend of continuous decline except for a transient increase from 10 to 15 WAB; it reached its peak level (0.712 mg/g) at 15 WAB and lowest level (0.473 mg/g) at 25 WAB ( Figure 1C ).

Exposure to cold led to increased food consumption ( Figure S4F ), and Panx1 Adip-/- mice showed a trend to increased body weight ( Figure S4G ).

Analysis of CXCL1 IHC and Cxcl2 in situ hybridization also showed a trend toward higher levels in Gnat3 -/- ;KC tissue, with staining being more prominent in areas that had progressed to carcinoma ( Figure 8 F and G ).

Among the subset items of CRGS, the following had no impact on mortality: size and location of the tumor, preoperative KPS score and preoperative neurological status; however, two factors showed a trend towards statistical significance: the presence of edema increased three-month mortality and the presence of concomitant diseases increased one-year mortality.

Preliminary data herein presented showed a trend of increased failed refill during the months of lockdown for lipid-lowering and biologic therapies.

The OCP or OCA results demonstrated that enrichment of TP53 mutations showed a trend for higher frequency in FLT3 amplification mCRC patients compared with in non‐ FLT3 amplification patients, but the difference did not reach statistical significance ( P = .16).

Unexpectedly, the total PD‐L1 only showed a trend that was negatively associated with prognosis, but no statistical differences were observed (Figure 6F ).