Thus, DS mice showed an evident motor hyperactivity measured in a computer-aided actimeter with elevated ambulation (t = 2.78, df = 28, p < 0.01), frequency of rears (t = 3.11, df = 28, p < 0.005), mean velocity (t = 2.03, df = 28, p < 0.05) and time spent in fast movements (t = 2.42, df = 28, p < 0.05), whereas their resting time showed a trend towards a reduction (t = 1.96, df = 28, p = 0.06) (see data in Supplementary File 1 ).
Animals resuscitated with plasma showed a trend towards lower syndecan-1 levels compared to the standard-volume crystalloid group (82 vs 99 ng/mL, p = 0.06) and had lower levels of VCAM-1 (424 vs 592 ng/mL, p < 0.01) compared to the standard volume crystalloid group, but not when compared to the low-volume crystalloid group.
Neonates who developed epilepsy were more likely to have ≥ 3 days of EEG-confirmed seizures compared to those without epilepsy ( p = 0.04) and showed a trend toward abnormal neurologic discharge examinations ( p = 0.06), consistent with prior NSR results (Table 2 ) [ 3 , 33 ].
The simple main effect of test time showed that the cognitive training group significantly improved on executive control, F (1,66) = 28.57, p < 0.001, η p 2 = 0.30, the active control group showed a trend of improvement, F (1,66) = 3.61, p = 0.06, η p 2 = 0.05, and the waitlist group did not show any improvement ( p = 0.84).
Patients with unilateral or bilateral ureteral obstruction showed a trend towards poor survival ( P =.06).
Postural sway with eyes open showed a trend for small 6.3 (−0.3 to 12.9, p = 0.06) mm 2 /s increase in moment of velocity.
Both archaeal and bacterial communities in rumen liquids and solids showed decreased dispersion from 8 weeks to 1 year to 2 years (PERMDISP, P < 0.05), except archaeal dispersion in rumen solids which only showed a trend (PERMDISP P = 0.06, Supplementary Table 5 ).
As for bacterial eradication, the meta-analyses showed a trend to increased microbiological clearance (RR 1.93, p=0.06), although it did not achieve statistical significance.
Treatment with BEMPEG plus nivolumab showed a trend toward increased PFS for these KIR-ligand present TNBC patients ( p = 0.06) (Fig. 2 A) and significantly improved OR ( p = 0.009; 36.4 vs. 0%) and tumor shrinkage ( p = 0.02; median change −23.5 vs. +12.8%) as compared to their KIR-ligand missing counterparts (Fig. 2 B, C ).
A study conducted by the US Lymphoma CAR-T Consortium showed that patients who received bridging therapy showed a trend toward inferior PFS compared to non-bridged patients (p = 0.06).
ANCOVA with baseline scores as covariate showed a trend toward significance for ECog scores (F 1,34 = 3.08, p = 0.06).
These results persisted for all‐cause mortality even after adjustment for demographic, clinical, and behavioral characteristics, and the findings showed a trend for significance after full adjustment for incident total CHD ( P =0.06).
The consolidative of RT showed a trend of improvement in OS in all patients (RT vs. no‐RT: HR = 0.35, 95% CI 0.12–1.03, p = 0.06; Figure 4A ), with no heterogeneity among studies ( p = 0.05).
Accordingly, GADA-positive subjects showed a trend towards higher levels of fasting glycaemia (298.0 ± 99.2 versus 208.8 ± 117.6, p = 0.06) than GADA-negative subjects ( Table 2 ). 4.
Efficacy of 1 st line and 2 nd line TKI treatments Median PFS on first-line erlotinib or gefitinib TKI treatment in those who turned out to be T790M positive (n = 22) and negative (n = 7) in later biopsies showed a trend to be different, 13.3 months (95% CI., 10–17) and 8.1 months (95% CI., 0–16) respectively (p = 0.06; Fig 1 ).
Results GBA-PD and iPD patients differed significantly regarding UPDRS-III scores (higher in GBA-PD; p = 0.01) and showed a trend towards a significant difference in the MoCA values (lower in GBA-PD, p = 0.06).
Similarly, completion of more races in the current season showed a trend to result in fewer DDs for shoulder injuries (Ratio =0.96 [95% CI =0.93–1.00], P =0.06).
The ENGENE-PSP study, the largest case-control study of PSP, assigned chemical exposure showed a trend of increased odds (OR = 1.20; 95% CI = 0.99–1.45; p = 0.06), and assigned metal exposure had a trend of increased odds (OR = 1.30; 95% CI = 1.00–1.70; p = 0.05) in the univariate analysis.
IL-1Ra showed a trend (p = 0.06) to be decreased in elderly women.
However, changes in overall Bern-scores did not correlate with clinical variables, although brain sagging showed a trend toward correlation with headache intensity reduction ( r = 0.37, p = 0.06).
In the multiple regression analysis predicting participation, none of the personality variables were found to be significant after accounting for gender and educational background, although persistence showed a trend of approaching significance (b=0.27, p =0.060).
However, children <10 years old (n = 10), showed a trend of a significant increase in IFN-γ + cells ( P = .06) at day 28, with the majority (8 of 10; 80%) showing an increase after the first dose ( Figure 4D–4F ).
The interaction effect Visualization*Difficulty was not significant but showed a trend, F (1,80) = 3.67, p = 0.06, η 2 = 0.003.
Among participants assigned to usual care (Pref-CON or Rand-CON) with baseline and 3-month follow-up data available (N=26), ACP discussions with loved ones showed a trend towards increase over time (50% vs 73%, p=0.06).
Postoperative RT only showed a trend toward a worse LRRFS than CCRT (HR, 6.15; 95% CI, 0.92–41.13; p = 0.06, Table 3 ).