76 Dependency, early neurological deterioration and death In the CATIS trial, 72 a secondary subgroup analysis for the primary outcome (combination of death and major disability (mRS 3–6) at 14 days or hospital discharge) showed a trend ( p = 0.06) towards interaction with ischaemic stroke subtypes.
Furthermore, the proportion of participants with a $10% decrease in average lesion area was significantly higher in the CPA group than the placebo group at weeks 3 ( P =0.05) and 6 ( P =0.02), and showed a trend at week 12 ( P =0.06).
At week 15, GOS‐fed mice also showed a trend toward a lower liver/body weight ratio (Figure 1K , p = 0.06).
In Cox proportional hazards models, high biomarker levels showed a trend toward conferring a higher risk of “not getting off treatment” as compared to low biomarker levels (for Gal‐9, hazard ratio [HR] 0.32, P = 0.06; for TNFRII, HR 0.24, P = 0.08; for CXCL10, HR 0.39, P = 0.1; for Gal‐1, HR 0.41, P = 0.1).
It showed a trend towards greater appropriateness ( p = 0.06) and it appeared to have “good” usability (median SUS = 76.4), although this also did not reach statistical significance ( p = 0.06).
Pulmonary function tests showed a trend toward improvement in VC% ( p = 0.06) and a significant increase in FEV 1 % ( p = 0.04) after the exercise + diet period, whereas no changes were observed for these variables in the other experimental conditions.
As shown in Table 6 , mTOR showed a trend of association with lymph node metastasis (OR = 1.72, 95%CI 0.98–3.01, P = 0.06) and late TNM stage (OR = 3.13, 95%CI 0.72–13.61, P = 0.13).
On the depression measure BDI, the ANCOVA showed a trend towards a main effect of learning support, F (1, 115) = 3.60, p =.06, d = 0.34, 95% CI [-0.02, 0.70].
A main effect of time was found for pTest ( P = 0.02) which only showed a trend for post concentrations to be elevated from the other time points (1.3-fold from pre, P = 0.06), whereas no group or time effects were found for sTest ( P > 0.05).
Association of T2 lesion metrics with clinical outcome scores In the OPERA II dataset, log-transformed baseline T2 TLV showed a trend ( p = 0.06) towards association with CDP24 when using the GT or model-predicted masks (Table 4 ) in the univariable CPH analysis.
In a study of 964 STEMI patients ( 7 ), adverse LV remodeling group showed a trend toward longer symptom-onset-to-balloon time than non-LV remodeling group (182 vs. 165 min, p=0.06), which was consistent with the present study (ischemic time ≥3 vs. <3 hours).
Patients’ neuropsychiatric symptoms showed a trend toward statistical significance as well (ORa = 1.09; p = 0.06).
[ 17 ] showed a trend toward decreased lymph node metastasis for sessile nonpedunculated tumors compared with nonpolypoid, exophytic or ulcerated lesions ( P = 0.06) in pT1 and pT2 rectal cancers.
Finally, the stratified analysis according to the stage of melanoma revealed that PDE5i use was associated with a significantly increased risk for in situ melanoma (two studies, 16 , 20 adjusted RR =1.31, 95% CI =1.01–1.69, P =0.04, I 2 =69%; Figure 4B ), showed a trend toward increased risk for localized melanoma (three studies, 16 , 20 adjusted RR =1.13, 95% CI =0.99–1.29, P =0.06, I 2 =23%; Figure 4B ), and showed a trend toward reduced risk for nonlocalized melanoma (three studies, 16 , 20 adjusted RR =0.79, 95% CI =0.62–1.01, P =0.06, I 2 =0%; Figure 4B ).
High bFGF and ICAM-1 levels also showed a trend toward a higher risk of death ( p = 0.06 both).
Analyses of the MALQOM scores in a subset of patients (n = 30) showed a trend towards a correlation with sensory thresholds in the fingertips (correlation co-efficient r s = −0.342, p = 0.06), but no relationship to thresholds on the hand or dorsum.
The number of lesions at T1 showed a trend towards predicting a higher chance of disease recurrence (p = 0.06).
Negative Assessment of SpondyloArthritis international Society (ASAS) classification criteria status at baseline showed a trend favoring enthesitis resolution in the MICE analysis ( P =0.06), which was not observed in the complete case analysis (P=0.2).
Recently, a randomized trial [ 52 ] on TACE versus proton therapy for hepatocarcinoma showed a trend toward improved 2-year PFS (31% vs. 48%, P = 0.06) and 2-year LC (45% vs. 88%, P = 0.06) favoring proton therapy, although the difference was not statistically significant.
Spontaneous inhibitory postsynaptic current (sIPSC) frequency recorded on M/T cells showed a trend toward increase after implicit learning (p=0.06, Kruskal-Wallis Anova followed by FDR-corrected permutation test, Enriched, n = 50 and Non-Enriched, n = 48) (for detailed statistics see Table 1 ), ( Figure 1H and Figure 1—source data 1 ) with no change in amplitude ( Table 1 , Enriched n = 48 and Non-Enriched, n = 46).
Pre-DDAVP VWF showed a trend towards lower levels in excellent responders (Ag: P =0.06, Act: P =0.07).
Statistical treatments showed a trend effect of tracking duration on home ranges area (Spearman's r = 0.52, n = 14, P = 0.06) and a lack of significant influence beyond 12 days of monitoring (Spearman's r = 0.38, n = 12, p = 0.23).
Summed scores showed a trend in the differences between Med-2 (30.55 ± 4.96), Med-3 (28.78 ± 6.25) and Med-4 (33.20 ± 6.41) students on perceptions around training (P=0.06), where Med-3 students tended to have lower scores than Med-2 or Med-4 students, although this was not statistically significant unless where indicated on the individual questions reported previously.
There were no significant differences in seropositivity among males versus females; RR 1.08 (95% CI 0.58–2.01), P = 0.82, while having a link with schools (teachers or students) showed a trend to be associated with seropositivity RR 1.85 (95% CI 0.96–3.57), P = 0.06.
In addition, the patients with bacteremia also showed a trend toward higher levels of TNF-α in plasma (median 3.65, IQR 0–7.28) compared with those with no bacteremia (median 0.53, IQR 0–4.51, P = 0.06).