Pro-apoptotic BCL2 associated X protein ( Bax ) had significantly increased expression in ovaries from offspring originating from PCEtOH-exposed pregnancies, while the pro-survival B cell leukemia/lymphoma 2 ( Bcl2 ) gene showed a trend ( p < 0.08) for increased expression.
In our cohort, FANCM showed a trend with increased BC risk (OR = 3.032, 95% CI 0.877–10.487, p = 0.08).
In multivariable regression analysis attempting to correct for established prognostic factors, ASCT as a time-varying covariate only showed a trend toward improvement ( P= 0.08).
Results Comparing pre- and post-tVR time-points, HIV-1 children with tVR ( n = 5) showed a trend to a decrease in ratio CD4/CD8 ( p = 0.08) but no significant differences were observed in plasma metabolites, lipids, or proteins.
The second germline DMR, the Nespas DMR, also showed a trend towards loss of imprinting during gametogenesis in both oocytes and spermatozoa (30.67 ± 1.54% in FD group vs. 35.00 ± 1.74% in controls for oocytes, P = 0.08; 2.71 ± 0.39% in FD groups vs. 5.28 ± 1.65%, in controls for spermatozoa, P = 0.08) (Figure 3 ).
Spliced variant of fibronectin, extra domain A ( ED-A ), showed a trend towards higher mRNA expression in the mucosa of IFX failure patients compared to IFX naïve patients (p = 0.08).
This difference did not reach statistical significance but showed a trend (chi-square test p = 0.08).
When transferred to HFD, by contrast, the VSG group on anti-GLP1R antibody (Ab) paradoxically ate significantly more than VSG mice given isotype control and showed a trend toward additional weight gain (p = 0.08 versus VSG controls) ( Figures 2 A, 2B, 2C, and 2F), suggesting that endogenous GLP-1 suppressed intake of HFD despite having little effect on ingestion of the liquid diet.
EMR showed a trend for a later onset after transplant than hematological relapse (6.1 vs 4.9 months) ( p = 0.08).
Only D95% of HR-PTV was predictive of a better overall survival ( p = 0.05), and showed a trend to a better PFS ( p = 0.08) ( Table 3 ).
In the RTOG 91-11, sequential CHT (with PF as induction) followed by RTX was compared to concomitant CRT and RTX alone in patients with locally-advanced laryngeal cancer (excluding T4 tumors with invasion through the full-thickness of the thyroid cartilage or base of tongue involvement), OS did not differ significantly between induction and concomitant arms, although the 10-year update analyses showed a trend toward a worse OS with concomitant CRT vs. sequential treatment (HR 1.25; 95% CI, 0.98–1.61; p = 0.08).
Indeed, the medium-sized difference between the delta 2 values of the two groups showed a trend towards statistical significance (P = 0.08; Cohen’s d = 0.72), being larger in the Waiting-first group than in the Training-first Group, as expected.
After adjustment for educational level, results showed a trend towards a lower maternal age at first pregnancy for CCSs compared to controls ( p = 0.08).
Active individuals with uncontrolled BP levels showed a trend (p = 0.08) of 17% higher risk of all-cause mortality compared to their peers with controlled BP levels.
In an analysis of covariance, BMI and age were not associated with impaired compensation after nephrectomy (absolute and relative ΔeGFR for BMI: P = 0.44 and P = 0.68; and for age: P = 0.78 and P = 0.56); individuals with VO showed a trend toward greater ΔeGFR ( P = 0.08), whereas the association in relative ΔeGFR was not statistically robust ( P = 0.14).
The assessment of lipid oxidative damage showed a trend of greater values in control newborns than in treated ones ( p = 0.08), but similar values of the antioxidant capacity.
PPS Univariate analysis for PPS1, showed a trend for better PPS in women treated with first-line ET as compared to ET plus CDK4/6i (HR: 0.63, C·I.: 0.37–1.06, p = 0.08) ( Figure S4 ). 3.2.4.
Moreover, low tidal volume ventilation increased the levels of glutamate ( p < 0.01), glycerol ( p < 0.05) and showed a trend towards higher lactate to pyruvate ratio ( p = 0.08) in cerebral microdialysate as well as higher levels of S-100B ( p < 0.05) in jugular venous plasma compared with medium–high tidal volume ventilation.
COVID-specific TUT showed a trend toward a significant correlation with CPT A’ , rho = − 0.110, p = 0.08.
Nevertheless, deep d showed a trend toward a bias of 11.2 minutes with N1 on ( P =.08), likely pointing to a slight underestimation with Fitbit of N3 sleep.
TSG-6 ameliorated renal inflammation The ratio of M1/M2 in RAS mice significantly increased compared to sham ( p = 0.03); RAS+TSG-6 showed a trend for decreased M1/M2 ( p = 0.08), which was no longer different from sham ( Figures 3 E and 3F).
As for the evaluation of mechanical properties, ID showed a trend of increase in MDX mice versus WT ( p = 0.08), which is consistent with what was observed at 3 months of age.
The median (Q1–Q3) CoMiSS value showed a trend towards being higher, with more prevalent loose stools in breast- than in formula-fed infants (4.0 (2–7) vs. 3.0 (1–4), respectively; p = 0.08); however, the difference was not significant.
Moreover, patients with VAF > 35% showed a trend for reduced overall survival ( p = 0.08; HR 1.5; 95% CI 0.9–2.4) without differences in thrombosis risk ( p = 0.9; HR 0.9; 95% CI 0.5–1.6) and leukemic progression ( p = 0.3; HR 2; 95% CI 0.5–7.7) ( Figure S3 ).
Indeed, administration of an intravitreally administered siRNA targeting the REDD1 mRNA (PF-04523655) in patients with diabetic macular edema showed a trend toward improvement in BCVA when compared to focal/grid laser (+5.8 letters with 3 mg PF-04523655 versus +2.4 letters with laser, p = 0.08) ( 18 ).