Using multiple meta-regression, the mean duration of illness showed a trend towards explaining this residual heterogeneity ( p = 0.0799, I 2 = 30.6%), whereas CPZ scores did not ( p = 0.2035) (see Supplementary Fig. 22 for bubble plot; Supplementary Table 13A, B for results).
NMES-RT + FES group showed a trend of a greater VO 2 peak in P1 [ p = 0.08; but not in P2 ( p = 0.25)] compared to PMT + FES.
They also showed a trend to less hospitalizations (0% vs. 21%, p = 0.08) and a statistically significant lower need to go to the emergency room (10% vs. 44%, p = 0.04) and to report falls (6% vs. 47%, p = 0.03).
In the experimental treatment versus bevacizumab subgroup, all studies failed to show a significant improvement of PFS, although HDAC‐inhibition with vorinostat and bevacizumab 37 showed a trend towards prolonged PFS (RR 0.63, 95% CI 0.37–1.06; p = 0.08; n = 85).
The septum showed a trend for a main effect of sex [ F (1, 24) = 3.34, p = 0.08], a main effect of age [ F (5, 24) = 7.87, p < 0.001], and no sex × age interaction [ F (5, 24) = 0.75, p = 0.59].
This was significantly greater than the CNR for FA (mean 1.21, standard deviation 0.45; two-tailed paired t -test p = 0.041) and showed a trend to being greater than the CNR for MD (mean 2.80, standard deviation 1.34; two-tailed paired t -test p = 0.080).
As we showed in Figure 4 A and B, 15-minute GLP-2 treatment significantly induced the phosphorylation level of MLC2 by ∼2.2 fold ( P = .0096) in jejunum tissue samples, similar as VEGFR3 phosphorylation, the induction of MLC2 phosphorylation was blocked by the VEGFR3 inhibitor MAZ-51 ( P = .042), and the other inhibitor SAR131675 showed a trend of inhibition ( P = .08), indicating that both GLP-2 and VEGFR3 play roles in regulating smooth muscle contractions.
Ureteral diameter showed a trend toward predicting outcomes, with unresolved cases having larger median diameters (15 mm vs. 10.5 mm, p ≈ 0.08).
Furthermore, CXCL12 showed a trend towards a shorter PFS (HR=2.30; 95% CI 0.86-5.97; p=0.08) in male patients.
Compared to patients treated with surgery alone, patients who received CTx alone showed a trend towards a higher median age (CTx alone = 3 years vs. surgery alone = 0.5 years, p = 0.08), more tumors in unspecified location (50% vs. 6.7%, p = 0.01) or thorax/mediastinum (25% vs. 4.4%, p = 0.07), a larger median tumor size (11.9 cm vs. 4.5 cm, p = 0.2), and more metastases at diagnosis (12.5% vs. 0%, p = 0.06).
The mean decline of PFTs per year during the study period was calculated for both groups of patients, and comparing them showed a trend to significance in FEV1 (−1.87% vs. −0.5% p=0.08) and FVC (−1.2% vs. +0.2% p=0.09), favoring the patients without isolation of Nocardia.
The NL3 R451C mice paired with the same genotype mice showed a trend for reduced social interaction compared to the WT/WT pairs ( p = 0.08) and compared to the NL3 R451C mice paired with WT mice ( p = 0.058).
A high tumour budding showed a trend towards an association with TSP ( P =0.080).
Analysis of change in PM alone showed a benefit to the intervention group (three studies, N = 340, SMD = −0.33, CI: [−0.62, −0.05], p = 0.02), while analysis of change in air nicotine alone showed a trend towards a benefit to the intervention group (air nicotine change: four studies, N = 421, p = 0.08).
The twice-weekly group showed a trend toward higher erythropoietin requirements ( P = 0.08).
Having metastasis in both visceral and bone locations showed a trend towards a shorter OS compared with having only one location affected ( p-value = 0.08, log-rank test).
Western blotting also showed a trend to higher levels of GAPDH-normalized E-cadherin in irradiated wounds (0.36 ± 0.04) compared to unirradiated wounds (0.22 ± 0.02) at day 28 (P=0.08, n=4 wounds/group).
LDL cholesterol concentrations showed a trend towards a decline over the duration of the study relative to placebo (Δ−0.2 [95%CI −0.5, 0.1] mmol/L, p = 0.08).
In quadriceps, PGC1α induction showed a trend for significance ( P = 0.08) at 40 days of age, suggesting that its dysregulation occurs very early in disease pathogenesis, with dysregulation increasing with disease progression.
The accuracy rate and number of CPR experiences showed a trend of negative association (P=0.08).
Also, patients with positive depression and/or anxiety screening at the end of Phase 2 showed a trend towards a lower likelihood of achieving target LDL-C <55 mg/dL ( n = 24, 72.7% vs. n = 112, 85.5%, p = 0.08).
Noteworthy, the total amount of SGs (across patients) in the original data showed a trend to be higher than chance level, as only 7.54% of the permuted data sets contain the same or a higher number of SGs ( p = .08; see Figure 4 ).
Injury assessment with the composite neuroscore showed a trend for impairment nine days post-injury (t(22) = 1.8, p = 0.08), although our previous study using this found no significant effect of bTBI 44 .
This difference did not reach statistical significance but showed a trend (chi-square test p = 0.08).
NUtE did not change with YoR under HN (R 2 0.09, P = 0.11), and showed a trend to decrease by 0.116 g DM g −1 N yr −1 under LN (R 2 0.11, P = 0.08) conditions ( Table 4 ; Fig. 5 f).