In contrast, Myostatin serum levels were comparable between patients on regular hemodialysis ( Figure 2 E) and patients with or without diabetes mellitus ( Figure 2 F), while patients with liver cirrhosis showed a trend towards higher Myostatin levels compared to non-cirrhotic patients ( p = 0.081, Figure 2 G). 3.3.
Bone volume (BV/TV) was also significantly decreased in wild-type mice exposed to CS (P<0.05), but showed a trend toward increase in IL-17A -/- mice with CS exposure (P=0.081) ( Figure 2E ).
For DLCO% decline, no significant differences were observed ( p = 0.43); however, nfHP patients showed a trend towards an immediate DLCO% increase of 3.38% after corticoid treatment initiation ( p = 0.081).
Accordingly, patients with high p16 showed a trend toward poor one-year survival rates (HR, 2.78, 95%CI, 0.88-8.73, p=0.081) and two-year (HR, 1.69, 95%CI, 0.79-3.66, p=0.181).
In primary-diagnosed cases, strong GPER intensity ( int = 3) showed a trend ( p = 0.081) of being associated with a high mitotic index (Ki67 ≥ 10%).
Although statistical significance was not demonstrated, longer treatment duration showed a trend of increased probability of union (p = 0.081).
The patients but not the controls showed a trend in the Condition effect [ F (1.59, 30.23) = 2.91, p = .081].
In contrast, MLL2 showed a significant decrease (p=0.017) and CREBBP showed a trend toward a decrease (p=0.081), consistent with mutations in these genes usually being early events in FL.
In addition, the mean HbT values during the post-SCS period showed a trend of significant difference among the five frequencies ( F (4,45) = 2.228, P = 0.081) in the prefrontal area.
The univariate analysis showed that children with a ≥20% FT4 decline were of similar age (7.7 ± 5.1 years versus 10.0 ± 5.7; p = 0.200), more often received antimetabolites (84% versus 67%; p = 0.049)) and showed a trend towards more frequent treatment with vinca-alkaloids (92% versus 80%; p = 0.081) compared with those with no decline or a decline of <20%.
In the controls, only the comparison between baseline and Flash showed a trend for a lower initial amplitude ( p = 0.081, FDR-corr.).
Excluding 90-day mortality, OS showed a trend toward improvement across surgical eras ( p = 0.081), increasing from 42.3 months (95% CI, 14.1–70.5) in 2000–2010 to 72.4 months (95% CI, 36.8–108.0) in 2011–2017, with the median not reached in 2018–2024 ( Fig. 2 B).
In this sensitivity analysis, the mean posterior globe thickness remained a significant independent predictor of any-eye TS (OR = 1799.02; 95% CI: 4.68-6.91×105; p=0.014), while age showed a trend toward protection (OR = 0.78; 95% CI: 0.59-1.03; p=0.081).
Across periods, total LFP power followed an inverted-U trajectory, peaking at period 3 and attenuating thereafter; the decrease from period 5 to period 6 showed a trend (Holm-adjusted p = 0.081; unadjusted p = 0.027).
Furthermore, the logistic regression analysis (Table 4 ) indicated that ODD was significantly associated with the likelihood of CDx‐related PMC ( p < 0.042), whereas BTD showed a trend that was not statistically significant ( p = 0.081). 3.4 Gap Between CDx and Drug Approval Dates in Japan and Comparison With the US In Japan, the median approval gap was −18 days (IQR: −52 to 0), indicating that CDx approval generally preceded or occurred simultaneously with drug approval (Figure 3b ).
CA125 showed a trend toward association that did not reach statistical significance ( p = 0.081).
When analyzing the mean signal intensity of TSPO immunoreactivity, the hippocampus showed a trend towards an increase ( p = 0.081, t = 2.513, df = 3.208) (Fig. 3 C).
After 28 days of treatment, it was found that the use of the ointment (post-dipping) showed a trend ( p = 0.081) in decreasing SCCs (log 10 /mL).
Pairwise comparison for CS trials within individual days showed a trend towards a slower CRonset time for Fc mice when compared to WT mice on D25 ( p = 0.081, 95% CI = [−7.85, 176.8], Figure 1 C).
The percentages of Foxp3-positive cells and CCR4-positive cells showed a trend toward positive correlation (Spearman’s ρ = 0.318 and P = .081 when excluding outlier results) ( Figure 3E ), and Foxp3-positive Tregs were more abundant in HAVCR2 WT SPTCLs ( P = .033) ( Figure 3G ).
At 85 dpi, the proliferative effect of tamoxifen on NG‐2 positive OPCs has vanished, and mice with tamoxifen treatment 38 dpi showed a trend for even less NG‐2 positive cells ( p = 0.081, Figure 6 ).
Before statistical adjustments, patients in the EVT group showed a trend towards more favorable outcomes (EVT: 20.0%, non‐EVT: 8.9%, p = 0.081).
Although the overall subset analysis according with the type of vaccine reported that age was not a significant ( p > 0.05) modifying factor ( Figure 3 A), the results showed a trend toward significance ( p = 0.081) for mRNA-based vaccines ( Figure 3 B).
Between minute 21 and 50, the CXL group was significantly flatter than the UV-only group (m = 0.01 ± 0.04 min −1 vs m = 0.09 ± 0.04 min −1 , p = 0.007), and showed a trend towards significant differences compared to the PBS-only and RIBO-only groups ( p = 0.081 and p = 0.090, respectively).
Accordingly, the results of the open field test showed a trend toward decreased anxiety ( Figure 2B , young: p = 0.081, aged: p = 0.292) and anxiety was significantly reduced in the young MIM KO cohort in the light/dark test [young: F (1,42) = 14.20, p = 0.001, aged: p = 0.812].