In contrast, Myostatin serum levels were comparable between patients on regular hemodialysis ( Figure 2 E) and patients with or without diabetes mellitus ( Figure 2 F), while patients with liver cirrhosis showed a trend towards higher Myostatin levels compared to non-cirrhotic patients ( p = 0.081, Figure 2 G). 3.3.
In addition, peptide B7 showed a trend to decrease the secretion of pro-inflammatory IFN-γ ( p = 0.081) and increase chemoattractant CCL-2 ( p = 0.076), while peptide B12 displayed a trend to increase the secretion of IL-23 ( p = 0.125).
However, the percent change in anteroposterior (AP) diameter showed a trend towards statistical significance: -3.86% [-26.5%, 18.7%] for the surgical side versus 0.32% [-20.9%, 21.5%] for the contralateral side (p = 0.081).
Associations between lesion size and performance Lesion volume had significant negative associations with performance on the Controlled Oral Word Association Test ( r =−0.63, p =0.0092) and the Semantic Fluency Test ( r =−0.53, p =0.033), and showed a trend towards a negative association with ER-VGT verb generation performance ( r =−0.45, p =0.081).
The treatment with HGnRH showed a trend of improving litter size compared with other treatments ( p = 0.081; Table 2 ). 4.
The high leptin group also showed a trend of the highest glucose level (168 vs. 229. vs. 231, p = 0.081).
After 28 days of treatment, it was found that the use of the ointment (post-dipping) showed a trend ( p = 0.081) in decreasing SCCs (log 10 /mL).
Association Between Ventral Epidural Spread and Pain Reduction Although ventral epidural spread showed a trend toward greater pain reduction, the association did not reach statistical significance (Kruskal–Wallis test, p = 0.081). 4.
Fisher’s exact test showed a trend toward higher prevalence of positive CAC in males (34.9% vs. 20.9%; odds ratio (OR) = 2.03, p = 0.081).
4 B, GSK-3β phosphorylation at serine-9 decreased significantly in MAG1-high mice (t (8) = 3.141, P = 0.0138), while GSK-3α phosphorylation at serine 21 showed a trend toward decrease (t (8) = 1.993, P = 0.0814). 3.5 Elevated cerebellar expression of MMP-9, especially in the purkinje cells Since increased MMP-9 levels were only found in the MAG1-high mice, we immunostained brain sections of this group with anti-MMP-9 antibodies.
Survival analysis of OV patients who received chemotherapy revealed that, compared to patients with low NEK1 expression, those with high NEK1 expression showed a trend toward improved overall survival (HR [95% CI] = 0.62 [0.36–1.06], p = 0.0814) ( Figure 6 B).
The male withdrawal group showed a trend toward HPA axis recovery; however, the comparison between treatment withdrawal groups did not reach significance ( P = .0815).
The protein expression of p-FoxO1 showed a trend to increase in response to HMB supplementation ( P = 0.0815).
3.3 Age and clinico-pathological associations Since our data showed a trend towards association between age (15 years) and EFS (Hazard ratio = 2.22; 95% confidence interval = 0.91 – 6.21; p = 0.0816; Table 3 ), we sought to determine the clinico-pathological associations with age.
The MeFS showed a trend of improvement, in all high-risk patients ( p = 0.0817, Figure 3 B) and those with high HuR cytoplasmic overexpression ( p =0.0800, Figure 3 D), but was not statistically significant.
Figure 4C shows the semi-quantitative analysis of proMMP-9 (pMMP-9) levels, which showed a trend towards significant differences between groups (p = 0.0817), with pMMP-9 levels being lower for pH 5.6, 7, and 9 treatments relative to positive controls and pH 4 treatments (see Table 2 for statistical analysis).
Female fetal growth was also entirely unaffected by LPS treatment (two-tailed t test, p = 0.9662), while growth of the male fetus showed a trend toward decreased fetal body weight after LPS treatment ( Fig. 1 F ; two-tailed t test, p = 0.0818).
While the study did not find a significant association between dosage and adverse events, the frequency of administration, particularly once-weekly infusions, showed a trend towards significance ( p = 0.082).
Among the comorbidities, asthma showed a trend toward association (aOR = 3.385, p = 0.082), although it did not reach statistical significance.
Multivariable analyses showed a trend for MELD ( P = 0.082) and for albumin ( P = 0.057), however significance at the level of 5% was not reached (Table 3 and Figure 3 ).
Compared with IFN-α therapy alone, those who received phlebotomy followed by IFN-α showed a trend towards a greater sustained virologic response (SVR) at an odds ratio of 2.32 ( p = 0.082) [ 73 ].
IL-1β showed a trend toward elevation (median 3.12 (1.46) vs. 2.20 (1.32) pg/mL, P = 0.082, r = 0.38), though not reaching statistical significance, which may reflect limited power in this subgroup analysis ( N = 30).
The second vancomycin dosing regimen (0.5 g q6h) showed a trend towards a protective effect compared to the conventional regimen (β = −0.646, OR = 0.524, 95%CI 0.246–1.064, P = 0.082).
Secondary mediation analyses testing specific taxa also failed to identify significant mediation pathways, though one genus showed a trend (indirect effect, p = 0.082).
Connectivity differences between the expressed breast milk and direct breastfeeding groups showed a trend towards significance ( p = 0.082), suggesting that the microbial communities in the expressed breast milk group may be more interconnected in terms of bacterial abundance changes.