RNA analysis in MLO‐Y4 osteocytic cells exposed to H 2 O 2 ‐induced oxidative stress revealed a significant increase in Sost (the gene encoding sclerostin) expression, while Wnt signalling–related genes ( Axin2 , Lef1 and Ctnnb ) showed a trend of compensatory upregulation, possibly reflecting a feedback response (Figure S4 ).
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In subgroup analyses stratified by LDL-C target achievement, patients with elevated LDL-C showed a trend toward lower event risk with decreasing TG levels.
Additionally, the ellagic acid content showed a trend of first increasing, then decreasing, and finally increasing again as the pressure increased, with the highest value of 5.97 mg/L observed at 400 MPa, which was significantly higher than that at the other pressures ( p < 0.05).
At 4 weeks, no significant differences were observed between the groups for any periodontal parameter, although Group C showed a trend toward lower values.
Use of low-level laser therapy (LLLT) showed a trend toward faster mucosal recovery but did not reach statistical significance (Table 2 - see PDF).
However, ARR-D consistently showed a trend toward higher AUCs than ARR-P, suggesting that DRC is not inferior to PRA in this setting.
Additionally, the STatin and Aspirin in Trauma (STAT) trial [ 12 ] found that aspirin and rosuvastatin, in addition to thromboprophylaxis, showed a trend toward reducing VTE events in trauma patients, and a study of patients undergoing total hip replacement found that atorvastatin was effective in preventing VTE [ 14 ].
The levels of Aβ40 showed a trend of increase in the WT+SSFO mice, but this increase was not significantly different from the Αβ40 levels in the WT+tdTom ( Figure 7 E).
In addition, WGCNA identified a co-methylation module that showed a trend-level association with SSRI response after adjustment for clinical covariates, and hub genes within this module were functionally linked to neuronal signaling in PPI network analysis.
Although Cdh2 expression was not significantly restores, it showed a trend toward increased expression.
CXCL16 also showed a trend of greater downregulation in the risk group (median log2 FC –0.15 in risk vs –0.07 in non-risk), although the difference was not statistically significant (p=0.40).
Analysis of corticosteroid exposure revealed that cumulative dose showed a trend towards increased risk at high exposure (adjusted OR (aOR) = 1.14, 95% CI 0.99 to 1.31), while average daily dose demonstrated a dose–response effect: 1–5 mg/day (aOR=1.31, 95% CI 1.13 to 1.52) and ≥5 mg/day (OR=2.48, 95% CI 2.16 to 2.86).
4 Is the Processing of Agreement Errors Modulated by Lexical Categories? The results above showed a trend of crossover pattern in the GramxAgrType interaction—internal agreement is read faster than external agreement in the match condition, but about the same or slower in the mismatch condition, suggesting that the mismatch penalty is larger for internal than for external agreement, even though the interaction effect is small.
Short-term outcomes At 1 month post-procedure, the AAS group showed a trend toward higher adverse outcomes compared to the lithotripsy group (AAS 17.1% (95% CI: 8.5% - 31.3%) vs.
Furthermore, as shown in Figure 3A , the mRNA expression levels of key adipogenic marker genes, Pparg ( p = 0.001), Fasn ( p = 0.038), and Fabp4 ( p = 0.022), were upregulated in the Intralipid group, while Acca expression ( p = 0.054) showed a trend of upregulation.
The △SOFA_5_1, reflecting the change in SOFA scores from day 1 to day 5, showed a trend toward clinical improvement over the treatment period.
Our data showed that for patients with tumors >10 cm in size, patients undergoing mastectomy showed a trend towards lower local recurrence.
Figure 1 demonstrates that during the follow-up period, the DRT and SRD groups generally showed a trend of visual improvement.
Although HbO concentrations showed a trend of increasing activation over time, specific pairwise comparisons between trials did not reach statistical significance.
Regarding secondary outcomes, the LM/S only showed a trend of significantly large improvements in environmental health-related QoL than the CAU at Week 7, whereas PLM demonstrated moderate to large improvements in insomnia symptoms, physical health-related QoL, overall lifestyle, nutrition, and stress management.
45-68 weeks old CSB mice did not show body weight differences compared to controls in females; however, males showed a trend toward weight loss ( p value 0.07) (Fig. 1A ).
2 C) showed a trend where the survival rate of patients in the high-risk stromal group was lower than that of the low-risk group.
Patients with lymphoma also showed a trend toward improved EFS, though this was not statistically significant (HR = 0.46, 95% CI: 0.20–1.07, p = 0.070).
Interpretation Although no significant difference was observed between the two groups in the primary endpoint, anamorelin showed a trend toward increased LBM with good tolerability, suggesting potential benefit in gastric cancer cachexia.
While DC values in PD patients were significantly different from those in PSP, they only showed a trend toward differentiation from MSA.