For example, participants exhibiting symptoms at Week 4 showed a trend toward elevated CCL4 (MIP-1β) levels compared to asymptomatic individuals.
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Therefore, serum DKK1 ≥3925.0 pg/mL at diagnosis showed a trend toward association with ESKD progression, but its significance did not exceed that of female sex, ESR, and serum creatinine at diagnosis.
[ 32 ] found no significant difference in PFS and OS between the two microspheres, though treatment with resin microspheres showed a trend toward improved OS.
Time‐to‐event analyses in the validation cohort showed a trend toward separation between ctDNA‐positive and ctDNA‐negative individuals.
While the regular-sweep protocol demonstrated higher treatment success (months 1 and 3), the slow-sweep protocol showed a trend toward greater reduction in the number of glaucoma medications, although this difference was not statistically significant.
8E ), this was not the case in most excitatory neurons, where it instead showed a trend in the other direction (Fig. 8C ).
During the period from 1990 to 2020, grassland area maintained an absolute advantage, with reduced fluctuations; wetland area showed a trend of first decreasing and then increasing, with 2010 as the turning point; forest and water area generally increased.
Although the right PCC did not reach significance, it showed a trend in the same direction, indicating that both hemispheres may contribute to awareness, but potentially with differing emphases.
3 ), Higher tumor grade showed a trend towards increased CDK4/6i eligibility (grade II vs.
However, both formulations showed a trend toward higher KDP retention in viable layers.
Conversely, for CH 3 I, despite the lack of a significant ΔVOC EX–IN from zero, all sponge species showed a trend toward increased removal with rising water concentration.
Besides, IMST also significantly reduced VAS scores (MD = −0.64, 95% CI: [−1.19, −0.10], I 2 = 95%, Moderate certainty) and showed a trend toward lower (MD = −6.96, 95% CI: [−15.85, 1.92], I 2 = 98%, Moderate certainty), indicating overall improvements in knee function, pain, and stiffness.
RT-qPCR analysis showed a trend of increased SYN1 and VGAT expression along with a small but confirmed increase in PVALB gene expression (fig.
Lymph node metastasis showed a trend toward worse survival but did not reach statistical significance (HR 1.704, 95% CI 0.976–2.975, p = 0.061).
For certain core indicators (such as body weight, disease activity index, inflammatory cell levels, and short-chain fatty acid content), the low-dose group showed a trend of superiority over the high-dose group.
Patients with a larger tumor burden—defined as a primary tumor size ≥ 2.5 cm, the presence of multiple pancreatic tumors, or tumor metastases—showed a trend toward higher serum LEAP2 levels compared with those with a lower tumor burden (median 30.9 ng/mL, range 2.02-79.1 ng/mL vs . 20.2 ng/mL, range 14.28-70.66 ng/mL; P = 0.118; Supplementary Figure 6 ).
The absent lymphocyte response (ILR-/PLR-) showed a trend towards worse overall survival in patients not undergoing neoadjuvant treatment, although this was not significant.
Although neither OANG dose caused significant changes, OANG-H showed a trend toward normalization ( Figure 6F ).
Although Asian studies showed a trend toward greater improvement in imaging outcomes, this difference did not reach statistical significance when formally tested for interaction ( p for interaction = 0.9201 for MACE and 0.0581 for LLL), suggesting that the overall treatment effect of DCB was largely consistent across populations despite baseline risk factor disparities.
Furthermore, after XMU-MP-1 treatment, the expression of senescence markers, such as P21 and γ-H2AX, decreased, while continued treatment with c-di-GMP showed a trend of enhanced senescent phenotypes ( Figure 4 H,I).
Postoperative pain and functional outcomes, including ODI and VAS scores, showed a trend toward improvement in the robotic group but did not reach statistical significance.
RASI use showed a trend towards lower odds of muscle wasting, although this association did not reach statistical significance (OR 0.70; 95% CI 0.44–1.10, P = 0.123).
Postmenopausal status showed a trend towards lower odds of suboptimal TVS, although this did not reach statistical significance.
An elevated body mass index showed a trend to be linked also to a higher incidence, but importantly, neither the age, nor hypertension, nor any other classic cardiovascular risk factor were associated with a higher incidence of silent PAF (Table 4 ).
Multivariate Cox regression analysis was adjusted for LVEF, the only covariable which showed a trend towards statistically significant differences between groups and had no collinearity.