Preliminary data suggest that CPEB4 knockdown mice showed a trend toward more arrhythmia sensitivity to catecholamines and had increased ventricular tachycardia inducibility with pacing ( Supplemental Figures 1B to 1D ).
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Indeed, children who received vitamin D showed a trend toward a greater improvement in respiratory distress by day 3 and shorter hospitalization than the other two groups.
However, when accounting for the total plasma volume obtained by each method (cardiac puncture: ~0.5 mL; perfusate: ~3 mL), total particle yield per animal showed a trend toward higher recovery with perfusate blood collection in both naïve and 50 kdyne SCI groups, though these differences did not reach statistical significance ( Figure 2 c,d). 3.2.
In a phase 3 trial as a booster, intranasal iNCOVACC was immunogenic and comparable to injectable boosters in serum neutralization; it also showed a trend toward increased salivary IgA, although mucosal antibody differences between intranasal and IM boosters were modest in magnitude[ 74 ].
For patients with different clinical stages, the surgical approach of NSM with BR showed a trend toward survival benefit (stage II: OS, HR: 0.59; 95 % CI: 0.34–1.02; BCSS, HR: 0.63; 95 % CI: 0.35–1.15; stage III: OS, HR: 0.54; 95 % CI: 0.29–1.02; BCSS: HR: 0.58; 95 % CI: 0.31–1.09).
For hs-cTnT, the association between its highest quartile (Q4) and NOAF showed a trend but did not reach statistical significance ( P = 0.056).
Although non-significant, their safety data showed a trend toward greater safety with apixaban.
For food-related stimuli, the Group × Time interaction for LPP amplitude did not reach statistical significance but showed a trend in the same direction.
In the Cox regression model, HPV16 positivity showed a trend toward an increased hazard of progression to CIN3, although the estimate was imprecise and did not reach statistical significance ( p = 0.146) ( Table 2 ).
In sex-stratified analyses, among women, perceived stress showed a moderate negative correlation with sleep quality, weak negative correlations with age and total cholesterol, and a very low negative correlation trend toward 8-hydroxy-2′-deoxyguanosine; in addition, perceived stress correlated positively (very low) with platelet count and illicit drug use and showed a trend toward a positive correlation with morbidity count.
This observation may reflect a reduction in systemic inflammatory activity, as indicated by the hs-CRP/albumin ratio and NLR, which showed a trend toward post-treatment decreases.
Higher M2 TAMs infiltration was associated with deeper tumor invasion (pT) and showed a trend toward advanced pTNM stage.
The spirulina pretreatment showed a trend toward an improved lipid profile in the HFD + IR condition, where TC was significantly less prominent.
Second, higher levels of ubiquinone showed a trend towards an association with higher all-cause mortality risk, which reached statistical significance only in the unadjusted model.
Patients with a Sister Mary Joseph nodule showed a trend toward better survival outcomes.
Compared with MTAP wild-type tumors (median 63 years, IQR 55–69), patients with MTAP deletion showed a trend toward older age; however, this difference did not reach statistical significance (Wilcoxon rank-sum test, p = 0.069).
In a prespecified exploratory analysis of the CD16A-158 polymorphism (V, high-affinity; F, low-affinity), patients with the CD16A-158FF genotype showed a trend toward improved OS with margetuximab compared with trastuzumab (median, 23.6 vs. 19.2 months; HR, 0.72; 95% CI, 0.52–1.00).
In groups 6–9 and 10–13, as fiber content increased, N 1 and N 2 showed a trend of initial increase followed by a decrease.
In the ordination plot, samples from Group C and Group M showed a trend of differential distribution along the coordinate axes.
As shown in Figure 2 , as the initiator amount increased, the gelation time of the supramolecular gel gradually shortened, while the viscosity showed a trend of first increasing and then decreasing.
Tumor-related factors: Tumor ulceration and necrosis showed a trend toward worse survival but did not reach statistical significance (HR = 0.52 for absence vs. presence; 95% CI: 0.23–1.16 and p = 0.112).
Paired comparisons showed a trend toward lower thresholds with CE-Chirp, although statistical significance was not reached due to the limited sample size.
Mice treated with resveratrol showed a trend toward increased time and distance on the rotarod compared to the D-gal-induced aging mice ( Figure 1 L,M).
Results The trial (N = 260) showed a trend towards fewer major renal or cardiovascular events in the integrated care group, particularly fewer heart failure hospitalisations.
In the FLT3 m subgroup ( n = 66), oral azacitidine improved relapse-free survival (RFS) and showed a trend toward improved OS [ 15 ].