“showed a trend”

However, Pal/car + Dex/T3 treatment to TAZ KO cells increased the level of Complex II subunit and showed a trend toward normalizing the levels of Complexes I, III, and V subunits ( Figures 3 A and S13 A).

HFNC showed a trend toward improved pulmonary scores, though not statistically significant (P>0.05).

Effectiveness At 1 year, the effectiveness assessments showed a trend toward improvement in the overall evaluation of PN performed by the investigator ( Figure 3A ), decrease in the target PN size on imaging ( Figure 3B ), and patient’s general self-assessment ( Figure 3C ) with selumetinib treatment.

12 Our study showed a trend toward a decline in the proportion of patients with HER2-positive MBC.

Cluster 3, which we identified as T cells, showed a trend of enrichment in OA IFP ( Figure 2 K).

DDC treatment showed a trend toward reduced expression of LRH-1 target genes; however, these changes were not statistically significant compared with chow controls ( Figure 3 A ).

However, DKT treatment partially reversed these changes and showed a trend towards restoring the F/B ratio, although this effect did not reach statistical significance (Fig. 5 C).

Regarding the improvement in frailty scores, combined interventions demonstrated the greatest improvement (SMD = -0.92, 95% CI: -1.43 to -0.40), followed by multicomponent exercise (SMD = -0.78, 95% CI: -1.15 to -0.43), while nutritional supplementation showed a trend toward improvement that did not reach statistical significance (SMD = -0.69, 95% CI: -1.67 to 0.27).

On the other hand, oleic acid (C18:1) content – which is the dominant component of the MUFA group – showed a trend opposite to linoleic acid.

25 , 33 Although the <18 years group showed a trend toward higher ADR incidence, the difference did not reach statistical significance, potentially due to the relatively lower prevalence of polypharmacy in this population.

Under the influence of these two pathogens, the isolation rates of GPB showed a trend of first increasing and then decreasing, but the overall linear trend lacked statistical significance.

A markedly positive CFB (>7%) was associated with higher ICU mortality and greater respiratory support requirements, whereas a markedly negative CFB (<−3%) showed a trend towards less favourable renal outcomes.

Additionally, the expression values of APOC4 and CDH1 measured by ELISA showed a trend to be correlated with those obtained by Tymora analysis in the discovery study (see Figure S1 ).

30 , 31 This immune complex-mediated hypothesis finds some support in our direct immunofluorescence(DIF) results, the rate of perivascular C3 appeared higher in HUV than in NUV, whereas NUV showed a trend towards more frequent basement membrane zone (BMZ) deposition.

The multiplicative interaction between cumulative early psychosocial score and PGS of MDD showed a trend towards statistical significance (p-interaction = 0.07) (Table C).

Epidemiological studies provide supporting evidence: in a population-based nested case–control study from Quebec involving 217 hospital-diagnosed epilepsy cases and 2170 matched controls, current statin users had a significantly lower risk of epilepsy (adjusted rate ratio = 0.65, 95% confidence interval [CI]: 0.46–0.92), while past users showed a trend toward reduced risk (adjusted rate ratio = 0.72, 95% CI: 0.39–1.30).

Notably, increasing concentrations of PIP 2 or PE showed a trend of decreased SLB fluidity, which could support a model where reduced diffusion enhances positive feedback signaling as has been described for cell polarity networks ( Chau et al. , 2012 ).

Specifically, proteins with high plasma-to-serum ratios matched known plasma-retained coagulation factors, while proteins with low ratios showed a trend toward serum-accumulated coagulation factors [ 24 ].

Median PFS for patients with ICIs-pretreated was 5.8 months (95% CI: 3.99–7.62) versus 4.5 months (95% CI: 2.91–6.09) for ICI-naïve patients, and the patients with ICIs-pretreatment showed a trend toward better PFS.

The pooled effect sizes across subgroups showed a trend toward larger SMDs at higher intervention frequencies and longer intervention periods; however, overall within-subgroup heterogeneity remained high, suggesting that residual heterogeneity may be driven by implementation differences such as dose parameters and intervention delivery quality.

AE patients with poor outcomes (n=5) showed a trend toward higher median CSF titres in the acute phase and at four months post-onset compared to patients with good outcomes (n=14); however, differences were not statistically significant.

The novel environment test showed a trend in the same direction but with a higher uncertainty than the other behavioural assays (HR = 1.44, 0.85–2.62).

However, MSSI showed a trend of reducing nirK abundance across most N levels, suggesting potential mitigation of N fertilizer loss from cropland ecosystems.

In the Luminal A subtype, while several genes such as CHEK1, PCNA, and CDC20 showed a trend toward prognostic relevance, none reached statistical significance under the log-rank test.

Besides, A subset of key pro-inflammatory cytokines (IL-6, IL-10, IFN-γ and IL-8) in cervical secretions showed a trend of higher mean levels in the persistence group than in the clearance group, though no statistically significant differences were detected between the two groups for all measured cytokines ( Supplementary Figure 2 ).