However, after drug administration, the DSG-H, DSG-M, and Positive groups showed a trend of weight recovery compared to the Model group.
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Group comparisons Independent-sample t -tests showed no statistically significant differences between groups in CBCL Thought Problems ( t = 1.78, df = 130, p =0.078) and Social Problems ( t = 1.70, df = 130, p = 0.092), although both domains showed a trend toward higher scores in the HW group.
Foxp3 overexpression was associated with restoration of GPX4 and SLC7A11 expression and a reduction in COX2 levels, indicating attenuation of ferroptosis molecular disturbances.In contrast, Foxp3 knockdown showed a trend towards suppression of HIF-1α and Hmox1 expression following SAH.
Albeit total CBF in the seated position ( P = 0.0822) and PCAv in the lateral position ( P = 0.0803) showed a trend to statistical significance between morning and afternoon.
In contrast, following seasonal A(H1N1) infection, the data showed a trend of positive correlation between early IgG and IgA titers against the infecting H1 and N1 antigens and increased disease severity (Fig. 2c, d ).
Lower concentrations of CoFe2O4/GO@Dex-CS nanozyme in combination with H2O2 showed a trend toward reduced viability but did not reach statistical significance.
Notably, compared with the model group, the intestinal microbiota structure of the OEH group showed a trend towards convergence with that of the control group.
Our beta diversity analysis showed a trend towards statistical significance, demonstrating that CC/UWL-AHF status explained ~1.6% of the variance in microbiome structure when compared to patients without ( p = 0.071).
Quantitative analysis of CoQ partitioning demonstrated that inhibition of the SCAP–SREBP pathway led to a significant decrease in non-mitochondrial CoQ, while the levels of mitochondrial CoQ showed a trend toward an increase ( Fig. 3, j and k ).
Notably, unlike the VAE, the MCVAE showed a trend toward enrichment ( , one-sided hypergeometric test) of FMRP targets in the mouse-only consensus set and the combined mouse–human dataset (Fig. 4B and Supplementary Table S6 ).
The presence of cirrhosis showed a trend toward increased risk but did not reach statistical significance in the adjusted model (adjusted OR = 2.82, 95% CI 0.99–8.05; P = 0.053).
Patients with DANE had higher risk of DTA growth ≥5 mm/y (odds ratio, 5.78 [1.58-24.0]) and showed a trend toward more reinterventions within 6 or 12 months (odds ratio, 4.62 [0.91-34.9] and 3.69 [0.85-19.8]; Figure 3 ).
In in vivo experiment, A485 showed a trend toward inhibiting BBN-induced bladder cancer invasion in mice.
[ 13 ] NHANES data analysis also showed a trend association between BPA and adult high-frequency hearing loss, but existing evidence is mostly limited to epidemiological relevance and lacks in-depth exploration of causal mechanisms.
Finally, consistent with other studies, 28 , 29 Asian and Native American patients showed a trend toward lower rates of morphine administration, although small sample sizes limit definitive conclusions.
Overall image quality showed a trend toward improvement with DL-denoising; conversely, DL-denoising was associated with a modest increase in perceived aliasing severity across most acquisition protocols; however, after correction for multiple comparisons, none of these differences reached statistical significance (Holm-corrected p>0.05 for all protocols).
Nevertheless, Widening a ER groups showed a trend toward a worse functional outcome.
In a clinical trial involving patients with SLE, metformin showed a trend toward reducing disease relapse, however, the difference relative to placebo was not statistically significant ( 73 ).
At the experimental endpoint, ex vivo BLI analysis of lung tissues showed a trend toward reduced metastatic seeding in TRMT112 KD mice (Fig. 7 G, H).
lactis V9 combined with αPD-1 therapy showed a trend of slowing tumor growth in both tumor models, suggesting that it may enhance the anti-tumor effects of immune checkpoint inhibitors.
Neoadjuvant therapy showed a trend toward increased LARS but did not reach statistical significance ( p = 0.30) (Table 6 ).
When comparing the two models, although Polg mut/mut mice showed a trend toward a more pronounced reduction in CSA than Mito-mice∆, the difference did not reach statistical significance (Fig. 2 F).
Clusters 3 and 4 showed a trend towards lower prevalence, possibly due to a higher incidence of coma and persistent coma, limiting delirium assessment.
Patients with positive PD-L1 expression (CPS ≥ 1) showed a trend toward better clinical outcomes than PD-L1 negativity, as evidenced by a higher ORR (64.5% vs. 40.0%) and longer median PFS (10.4 months vs. 4.0 months) as assessed by IRC, as well as improved survival (median OS: 15.4 months vs. 13.3 months; 12-month OS rate: 61.3% vs. 50.0%) (Table 4 ).
Overall, the combination of acupuncture stimulation therapy with standard treatment showed a trend toward positive improvement to varying degrees across all outcome measures.