Treatment with SD-282 at a low dose showed a trend toward reducing the inflammation but the difference was not significant.
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Co-transfection of siRNA-Sp4 showed a trend to decreased levels of promoter activity that did not reach significance.
1B ), and showed a trend towards lower cell numbers in the draining lymph nodes of the genital tract ( Fig. 1B ).
However, examination of the individual patients' data showed a trend for no change in subjects presenting with low cGMP basal values (<1.5 fmol close to the detection limit), but a clear decrease (approximately 50%) after LD administration in subjects presenting with higher basal values (>3.0 fmol, patient-2 and 6; highlighted in Table 2 ).
Kaplan-Meier analysis showed a trend toward an increased OS rate for patients with hypomethylated CpG1, however, the difference did not reach statistical significance (P = 0.22, log-rank = 1.51; Figure 3 ).
In that head-to-head study (a 30-week, open-label trial that included 295 patients with Type 2 diabetes), patients’ treatment satisfaction was also measured by the DTSQ and, although the results showed a trend towards greater treatment satisfaction with exenatide once weekly vs. twice daily, the difference was not statistically significant [ 7 ].
Additionally, subjects with elevated baseline CRP and ESR showed a trend towards a reduction of circulating CRP levels or normalisation of ESR at least once within the first 4 weeks after administration.
The group with cerebral swelling was younger, had a higher opening pressure on lumbar puncture, and showed a trend to more frequent convulsions.
GRP94 was up-regulated by IFN treatment, and GRP78 showed a trend toward increased levels, but was determined to be not significant.
Randomized controlled preclinical and clinical studies with detergent-based microbicides such as nonoxynol-9 showed a trend towards evidence of harm, with increased incidence of not only HIV-1 infection, but also HSV-2 and HPV seen in the experimental arms [33] , [34] , [35] , [36] , [37] .
As a matter of fact, stratifying our analyses by DMARD treatment over the first 5 years, earlier remission showed a trend of association with better functional outcome in the subset of patients treated during the followup.
In a descriptive sense, as shown in Figure 2 , the ASI and GAGS scores showed a trend of improvement in the flutamide group versus the cyproterone-estradiol combination group.
Mean CRP and baseline DAS-28 showed a trend to be increased in patients with a new vertebral fracture (Table 3 ), but were not independent predictors of future vertebral fractures.
MSC with high osteogenic capacity underwent better chondrogenesis and showed a trend to better adipogenesis.
Accordingly, treatment with vitamin D in experiment 2 increased serum 25(OH)D levels, urinary calcium excretion also showed a trend to increase (but not statistically significant), and serum PTH levels showed a trend to decrease (but not statistically significant) in both the control and hyponatremic animals and slightly reduced the degree of reduction of bone mass ( p < .05; see 1 B ).
In spite of this, her scores showed a trend of improvement on two out of three of her highest scoring schemas.
Also in our study, the wt XRCC3 Thr241Met showed a trend for having a protective role towards of erythema, according to data reported by Popanda et al.
The XRCC1 Arg399Gln genotypes showed a trend of decreased risk of papillary thyroid carcinoma; however, it was not significantly different from those of the other genotypes.
In a separate study, treatment of WT mice with the histamine H1-receptor antagonist hydroxyzine hydrochloride at 40 μg/ml in drinking water prior to and during piroxicam exposure also showed a trend toward increased ulcer incidence (60%; n = 10).
21 reported that VH-IVUS showed a trend towards larger percentage of FF plaque volume in the no-reflow group than in the normal-reflow group.
Although not statistically significant, rates of miscarriage (IMSI:15.3% vs ICSI:31.7%), ongoing pregnancy (IMSI:22% vs ICSI:13%) and live births (IMSI:21% vs ICSI:12%) showed a trend towards better outcomes in the IMSI group.
Quantitative analysis showed a trend of thickness reduction in the total retina, with significant difference found in the group injected with 200 μM of Hcy-T, as compared to that of the sham injection control group ( Figure 2F ).
Further analyses also showed a trend for each of the 10 ACT concepts, of increasing mean values from low to high levels of instrumental research use, commencing at scale point 3.
Nevertheless, Map in samples storage at −70°C showed a trend for twice (OR = 2.2) longer survival which can result from the relatively small sample size stored at −70°C.
This was significantly enhanced in WAT and showed a trend toward increase in liver and skeletal muscle of HFD-Hp −/− mice compared with HFD-WT mice ( Fig. 4 E–G ).