[ 240 ] analysed 59,796 men and women of a Japanese cohort and found no significant risk for diabetes for milk consumption in men, whereas women exposed to > 200 g milk/day showed a trend to lower diabetes risk, although not reaching statisitical significance.
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The majority of the inflammatory genes showed a trend towards increased expression with HCA ( Table 4 ).
[ 50 ] showed that supplementation of CLA (50:50 isomer blend of 9- and 10-CLA) with or without vitamin E for 8 wk showed a trend to increase in malondialdehyde (a marker of lipid peroxidation) in overweight type 2 diabetic patients.
6g,h ), the neurons from FD subjects showed a trend toward decrease in number ( Fig. 6i ; 16.5 ± 1.1 HC neurons/well, n=60 wells; 14.1 ± 1.1 FD neurons/well, n=60 wells; difference between HC neurons/well and FD neurons/well 2.3 ± 1.5, n=60 wells; random intercept mixed-effects model p=0.26) and a robust reduction in neurite outgrowth per cell ( Fig
Similarly, average methylation at non promoter-associated regions showed a trend toward hypermethylation in 112 DCGs (5% FDR), but no significant differences were associated with the remaining 93% of the DCGs (Supplementary Figure 10B ).
The data showed a trend for decreased memory but no significant memory impairment ( Fig. 3b ), therefore all subsequent experiments were conducted using 0.1 mM Aβ 25-35.
Blood pH was significantly decreased in these mice, and they also showed a trend to elevated blood urea concentration, relative to vehicle-treated WT controls.
In contrast, most of the naive CD8 + T cells in spleen corresponded to CD31 + thymic although CD8 + T cells obtained from “4x” SmyleDCpp65 showed a trend towards higher numbers of CD31 − central naive CD8 + T cells ( Figure 6g ).
After 1 day of micromass culture, transcripts 1 + 4, 2, 5, 6, and 7 were significantly decreased, while transcripts 3, 8, and 9 showed a trend towards decrease, compared to transcript levels immediately prior to plating in micromass (Figure 2 A).
33 Controls in our study showed a trend toward decreased coherence in between hemisphere; however, within hemisphere there was an increase.
This trial showed a trend for reduction of LOS during the initial encounter (0.5 days) and for overall hospitalizations (0.7 days) within 90 days in the ProADM-enhanced intervention group compared to the control group [ 17 ].
A permanova-based test showed a trend toward a difference between all EoE and non-EoE control esophageal samples in community proportions which did not reach statistical significance (weighted UniFrac distances; Adonis P values for EoE versus non-EoE control subjects: P = 0.06).
Interestingly, glucose and lactate showed a trend change around 45 minutes into the exercise, 12 minutes before the first physical evidence of exhaustion and 42 minutes before full exhaustion (indicated by red ovals).
Therefore, the trans-tendon repair technique showed a trend towards superior outcomes in the re-tear rate aspect with regard to the management of articular-sided partial-thickness rotator cuff tears (PTRCTs) of more than 50 % thickness.
Only two studies showed a significant decrease of HCC incidence; whereas the others showed trend of decrease but one showed a trend of increase.
Further, the analysis of patients with low intratumoral expression levels of IL-17A (87 ± 14 months) showed a trend to reduced survival times compared to patients with high intratumoral IL-17A expression (117 ± 11 months) though the difference was not statistically significant (P = 0.211) (Figure 6 B).
Further, in combination with cetuximab, a number of compounds showed a trend towards decreased viability, although results did not rise to statistical significance.
[ 15 ] found that the overall incidence of PONV during the 24 h after surgery showed a trend toward a lower incidence in the dexmedetomidine group, but it did not reach statistical significance.
When the samples were grouped on the basis of dietary habits, the PLS-DA models showed a trend of differentiation according to the geographical origin of the samples in the omnivore and vegan subjects (at least for Bari, Parma and Bologna), while the samples from Torino were only clearly separated in the case of the ovo-lacto-vegetarian population ( Fig 5 ).
The oral CEE group also showed a trend in improvement on measures of anger-hostility and memory recall of printed material. 21 Ultimately, the recent results of the KEEPS and the KEEPS Cog study are that if there proves to be a window of time in the early post menopause when initiation of long-term HT has a net beneficial effect, then women can feel reassured that treatment of their menopausal symptoms when they are likely to be the most severe, can concurrently protect their vascular system, reduce bone reabsorption, or even elicit neuroprotection from dementia in late life. 21 , 22 4.
Notably, Mapt −/− neurons also showed a trend toward reduced A5 positivity compared to Mapt +/+ neurons.
Gold et al 4 reported SFTs greater than 10 cm had a statistically significant worse outcome for metastasis and also showed a trend toward an increased local recurrence disease survival.
In this study, high FOXA1-expressing tumours showed a trend towards being associated with better outcomes, although it was not statistically significant, corresponding to the results of previous studies.
As the authors note, IVC induction showed a trend to improved efficacy and reduced TF in the ALMS maintenance study. 5 Unfortunately, the relative role of the maintenance agents are not assessed.
In a randomized phase 2 trial of rilotumumab±epirubicin/cisplatin/capecitabine in gastric or oesophagogastric junction cancer, patients receiving rilotumumab showed a trend towards improved survival, especially in MET-positive patients, but no clear dose–response relationship was observed.